Matthew W. Jacobson
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View article: A kV–MV approach to CBCT metal artifact reduction using multi-layer MV-CBCT
A kV–MV approach to CBCT metal artifact reduction using multi-layer MV-CBCT Open
Objective . To demonstrate that complete cone beam CT (CBCT) scans from both MV-energy and kV-energy LINAC sources can reduce metal artifacts in radiotherapy guidance, while maintaining standard-of-care x-ray doses levels. Approach . MV-CB…
View article: Impact of a novel multilayer imager on metal artifacts in MV-CBCT
Impact of a novel multilayer imager on metal artifacts in MV-CBCT Open
Objective . Megavoltage cone-beam computed tomography (MV-CBCT) imaging offers several advantages including reduced metal artifacts and accurate electron density mapping for adaptive or emergent situations. However, MV-CBCT imaging is limi…
View article: Beam's-Eye-View Imaging of Liver SBRT With a Novel Multi-Layer Imager
Beam's-Eye-View Imaging of Liver SBRT With a Novel Multi-Layer Imager Open
View article: Improvements in beam’s eye view fiducial tracking using a novel multilayer imager
Improvements in beam’s eye view fiducial tracking using a novel multilayer imager Open
Purpose. Electronic portal image devices (EPIDs) have been investigated previously for beams-eye view (BEV) applications such as tumor tracking but are limited by low contrast-to-noise ratio and detective quantum efficiency. A novel multil…
View article: Frequency-dependent optimal weighting approach for megavoltage multilayer imagers
Frequency-dependent optimal weighting approach for megavoltage multilayer imagers Open
Multi-layer imaging (MLI) devices improve the detective quantum efficiency (DQE) while maintaining the spatial resolution of conventional mega-voltage (MV) x-ray detectors for applications in radiotherapy. To date, only MLIs with identical…
View article: Abbreviated on-treatment CBCT using roughness penalized mono-energization of kV-MV data and a multi-layer MV imager
Abbreviated on-treatment CBCT using roughness penalized mono-energization of kV-MV data and a multi-layer MV imager Open
Simultaneous acquisition of cone beam CT (CBCT) projections using both the kV and MV imagers of an image guided radiotherapy system reduces set-up scan times—a benefit to lung cancer radiation oncology patients—but increases noise in the 3…
View article: Clinical translation of a new flat-panel detector for beam’s-eye-view imaging
Clinical translation of a new flat-panel detector for beam’s-eye-view imaging Open
Electronic portal imaging devices (EPIDs) lend themselves to beams-eye view clinical applications, such as tumor tracking, but are limited by low contrast and detective quantum efficiency (DQE). We characterize a novel EPID prototype consi…
View article: GPU-accelerated Monte Carlo simulation of MV-CBCT
GPU-accelerated Monte Carlo simulation of MV-CBCT Open
Monte Carlo simulation (MCS) is one of the most accurate computation methods for dose calculation and image formation in radiation therapy. However, the high computational complexity and long execution time of MCS limits its broad use. In …
View article: Automated MV markerless tumor tracking for VMAT
Automated MV markerless tumor tracking for VMAT Open
Tumor tracking during radiotherapy treatment can improve dose accuracy, conformity and sparing of healthy tissue. Many methods have been introduced to tackle this challenge utilizing multiple imaging modalities, including a template matchi…
View article: A rapid, accurate image simulation strategy for mega-voltage cone-beam computed tomography
A rapid, accurate image simulation strategy for mega-voltage cone-beam computed tomography Open
Intensive computation time is required to simulate images of electronic portal imaging device (EPID) using Monte Carlo (MC) technique, limiting the development of applications associated with EPID, such as mega-voltage cone-beam computed t…
View article: Evaluation of image quality and task performance for a mobile C-arm with a complementary metal–oxide semiconductor detector
Evaluation of image quality and task performance for a mobile C-arm with a complementary metal–oxide semiconductor detector Open
We assessed interventional radiologists' task-based image quality preferences for two- and three-dimensional images obtained with a complementary metal-oxide semiconductor (CMOS) flat-panel detector versus a hydrogenated amorphous silicon …
View article: Low‐dose megavoltage cone‐beam computed tomography using a novel multi‐layer imager (MLI)
Low‐dose megavoltage cone‐beam computed tomography using a novel multi‐layer imager (MLI) Open
Purpose The feasibility of low‐dose megavoltage cone‐beam acquisition (MVCBCT) using a novel, high detective quantum efficiency (DQE) multi‐layer imager (MLI) was investigated. The aim of this work was to reconstruct MVCBCT images using th…
View article: Task-driven source–detector trajectories in cone-beam computed tomography: II. Application to neuroradiology
Task-driven source–detector trajectories in cone-beam computed tomography: II. Application to neuroradiology Open
We apply the methodology detailed in "Task-driven source-detector trajectories in cone-beam computed tomography: I. Theory and methods" by Stayman et al. for task-driven optimization of source-detector orbits in cone-beam computed t…
View article: A novel method for fast image simulation of flat panel detectors
A novel method for fast image simulation of flat panel detectors Open
We have developed a novel method for fast image simulation of flat panel detectors, based on the photon energy deposition efficiency and the optical spread function (OSF). The proposed method, FastEPID, determines the photon detection usin…
View article: Clinical Translation of the LevelCheck Decision Support Algorithm for Target Localization in Spine Surgery
Clinical Translation of the LevelCheck Decision Support Algorithm for Target Localization in Spine Surgery Open
View article: Penalized-Likelihood Reconstruction With High-Fidelity Measurement Models for High-Resolution Cone-Beam Imaging
Penalized-Likelihood Reconstruction With High-Fidelity Measurement Models for High-Resolution Cone-Beam Imaging Open
We present a novel reconstruction algorithm based on a general cone-beam CT forward model, which is capable of incorporating the blur and noise correlations that are exhibited in flat-panel CBCT measurement data. Specifically, the proposed…
View article: A line fiducial method for geometric calibration of cone-beam CT systems with diverse scan trajectories
A line fiducial method for geometric calibration of cone-beam CT systems with diverse scan trajectories Open
Modern cone-beam CT systems, especially C-arms, are capable of diverse source-detector orbits. However, geometric calibration of these systems using conventional configurations of spherical fiducials (BBs) may be challenged for novel sourc…
View article: Planning, guidance, and quality assurance of pelvic screw placement using deformable image registration
Planning, guidance, and quality assurance of pelvic screw placement using deformable image registration Open
Percutaneous pelvic screw placement is challenging due to narrow bone corridors surrounded by vulnerable structures and difficult visual interpretation of complex anatomical shapes in 2D x-ray projection images. To address these challenges…
View article: Correction of patient motion in cone-beam CT using 3D–2D registration
Correction of patient motion in cone-beam CT using 3D–2D registration Open
Cone-beam CT (CBCT) is increasingly common in guidance of interventional procedures, but can be subject to artifacts arising from patient motion during fairly long (~5-60 s) scan times. We present a fiducial-free method to mitigate motion …
View article: Effects of Image Quality on the Fundamental Limits of Image Registration Accuracy
Effects of Image Quality on the Fundamental Limits of Image Registration Accuracy Open
For image-guided procedures, the imaging task is often tied to the registration of intraoperative and preoperative images to a common coordinate system. While the accuracy of this registration is a vital factor in system performance, there…
View article: Fundamental limits of image registration performance: effects of image noise and resolution in CT-guided interventions
Fundamental limits of image registration performance: effects of image noise and resolution in CT-guided interventions Open
Analysis of the CRLB for image registration is an important step toward understanding and evaluating an intraoperative imaging system with respect to a registration task. While the CRLB is optimistic in absolute performance, it reveals a b…
View article: Deformable 3D-2D registration for guiding K-wire placement in pelvic trauma surgery
Deformable 3D-2D registration for guiding K-wire placement in pelvic trauma surgery Open
Pelvic Kirschner wire (K-wire) insertion is a challenging surgical task requiring interpretation of complex 3D anatomical shape from 2D projections (fluoroscopy) and delivery of device trajectories within fairly narrow bone corridors in pr…
View article: Intraoperative evaluation of device placement in spine surgery using known-component 3D–2D image registration
Intraoperative evaluation of device placement in spine surgery using known-component 3D–2D image registration Open
Intraoperative x-ray radiography/fluoroscopy is commonly used to assess the placement of surgical devices in the operating room (e.g. spine pedicle screws), but qualitative interpretation can fail to reliably detect suboptimal delivery and…
View article: Spinal pedicle screw planning using deformable atlas registration
Spinal pedicle screw planning using deformable atlas registration Open
Spinal screw placement is a challenging task due to small bone corridors and high risk of neurological or vascular complications, benefiting from precision guidance/navigation and quality assurance (QA). Implicit to both guidance and QA is…
View article: Registration of MRI to intraoperative radiographs for target localization in spinal interventions
Registration of MRI to intraoperative radiographs for target localization in spinal interventions Open
Decision support to assist in target vertebra localization could provide a useful aid to safe and effective spine surgery. Previous solutions have shown 3D-2D registration of preoperative CT to intraoperative radiographs to reliably annota…
View article: Deformable 3D-2D Registration of Known Components for Image Guidance in Spine Surgery
Deformable 3D-2D Registration of Known Components for Image Guidance in Spine Surgery Open
A 3D-2D image registration method is reported for guiding the placement of surgical devices (e.g., K-wires). The solution registers preoperative CT (and planning data therein) to intraoperative radiographs and computes the pose, shape, …