Michael Tu
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View article: Nomogram for predicting post-transarterial chemoembolization survival in recurrent patients with hepatitis B virus-associated hepatocellular carcinoma
Nomogram for predicting post-transarterial chemoembolization survival in recurrent patients with hepatitis B virus-associated hepatocellular carcinoma Open
In the population of patients with hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) experiencing postoperative recurrence and undergoing subsequent transarterial chemoembolization (TACE), a comprehensive model for outcome …
View article: The DOGE Ate My Data: Lessons from Europe for Rebuilding the Health Data Linkage Infrastructure in the US after Trump
The DOGE Ate My Data: Lessons from Europe for Rebuilding the Health Data Linkage Infrastructure in the US after Trump Open
Health data linkage systems are essential for understanding and addressing health inequalities, yet the United States' system—already constrained by legal and institutional limitations—has been further eroded by the second Trump administra…
View article: Assessment of the reliability and quality of pancreatic cancer related short videos on mainstream platforms: cross-sectional study
Assessment of the reliability and quality of pancreatic cancer related short videos on mainstream platforms: cross-sectional study Open
Pancreatic cancer-related short videos are of medium quality and low reliability, particularly on Chinese platforms. Videos from medical professionals are more trustworthy. There is a need for better curation and algorithms to ensure accur…
View article: A System Not of Our Making: Electoral and Institutional Constraints on Indigenous Self-determination in Taiwan
A System Not of Our Making: Electoral and Institutional Constraints on Indigenous Self-determination in Taiwan Open
This research note examines the Indigenous legislative electoral system in Taiwan, discussing how the separation into “Mountains” and “Plains” reflects a legacy of colonial classification and continues to marginalize Indigenous voices in c…
View article: Exploring the Basic Principles of Psychosomatic Interaction Therapy in Mongolian Medicine: A Prospective on the concept of Energy Medicine in Oriental Traditions
Exploring the Basic Principles of Psychosomatic Interaction Therapy in Mongolian Medicine: A Prospective on the concept of Energy Medicine in Oriental Traditions Open
Psychosomatic interaction therapy in Mongolian medicine, developed by Dr. Nagunbilig in China in the early 1990s, is a form. of Chinese-style. psychosomatic psychotherapy. Rooted in the classical theory of mind-body interaction in traditio…
View article: Piezo-type mechanosensitive ion channel component 1 (PIEZO1) is upregulated in peripheral arterial disease (PAD) and a novel murine PAD model
Piezo-type mechanosensitive ion channel component 1 (PIEZO1) is upregulated in peripheral arterial disease (PAD) and a novel murine PAD model Open
Peripheral artery disease (PAD) is the third most common atherosclerotic bed. PAD is associated with increased risk of limb loss and death, but the mechanisms driving site-specific arterial remodeling in PAD remain unclear. This work uniqu…
View article: Nutrient competition predicts gut microbiome restructuring under drug perturbations
Nutrient competition predicts gut microbiome restructuring under drug perturbations Open
Human gut commensal bacteria are routinely exposed to various stresses, including therapeutic drugs, and collateral effects are difficult to predict. To systematically interrogate community-level effects of drug perturbations, we screened …
View article: The QUATRO Application Suite: Quantum Computing for Models of Human Cognition
The QUATRO Application Suite: Quantum Computing for Models of Human Cognition Open
Research progress in quantum computing has, thus far, focused on a narrow set of application domains. Expanding the suite of quantum application domains is vital for the discovery of new software toolchains and architectural abstractions. …
View article: Variability in Severe Acute Respiratory Syndrome Coronavirus 2 IgG Antibody Affinity to Omicron and Delta Variants in Convalescent and Community mRNA-Vaccinated Individuals
Variability in Severe Acute Respiratory Syndrome Coronavirus 2 IgG Antibody Affinity to Omicron and Delta Variants in Convalescent and Community mRNA-Vaccinated Individuals Open
The emergence of the omicron and delta variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has begun a number of discussions regarding breakthrough infection, waning immunity, need and timing for vaccine boosters, and …
View article: An EcR probe reveals mechanisms of the ecdysone-mediated switch from repression-to-activation on target genes in the larval wing disc
An EcR probe reveals mechanisms of the ecdysone-mediated switch from repression-to-activation on target genes in the larval wing disc Open
Fluctuating levels of steroid hormones provide both systemic and local cues to synchronize metazoan development and control germline and homeostatic processes. The main steroid hormone in Drosophila is ecdysone (Ec), which upon binding of …
View article: Variability in SARS-Cov-2 IgG Antibody Affinity To Omicron and Delta Variants in Convalescent and Community mRNA Vaccinated Individuals
Variability in SARS-Cov-2 IgG Antibody Affinity To Omicron and Delta Variants in Convalescent and Community mRNA Vaccinated Individuals Open
The emergence of Omicron and Delta variants of SARS-CoV-2 has begun a number of discussions regarding breakthrough infection, waning immunity, need and timing for vaccine boosters and whether existing mRNA vaccines for the wildtype strain …
View article: The Kinetics of COVID-19 Vaccine Response in a Community-Vaccinated Population
The Kinetics of COVID-19 Vaccine Response in a Community-Vaccinated Population Open
We used a noninvasive electrochemical quantitative assay for IgG Abs to SARS-CoV-2 S1 Ag in saliva to investigate the kinetics of Ab response in a community-based population that had received either the Pfizer or Moderna mRNA-based vaccine…
View article: The Kinetics of COVID-19 Vaccine Response in a Community Vaccinated Population
The Kinetics of COVID-19 Vaccine Response in a Community Vaccinated Population Open
We used a noninvasive electrochemical quantitative assay for IgG antibodies to SARS-CoV-2 S1 in saliva to investigate the kinetics of antibody response in a community-based population who had received either the Pfizer or Moderna mRNA-base…
View article: Longitudinal Circulating Tumor DNA Analysis in Blood and Saliva for Prediction of Response to Osimertinib and Disease Progression in EGFR-Mutant Lung Adenocarcinoma
Longitudinal Circulating Tumor DNA Analysis in Blood and Saliva for Prediction of Response to Osimertinib and Disease Progression in EGFR-Mutant Lung Adenocarcinoma Open
Background: We assessed whether serial ctDNA monitoring of plasma and saliva predicts response and resistance to osimertinib in EGFR-mutant lung adenocarcinoma. Three ctDNA technologies—blood-based droplet-digital PCR (ddPCR), next-generat…
View article: Development and validation of a quantitative, non-invasive, highly sensitive and specific, electrochemical assay for anti-SARS-CoV-2 IgG antibodies in saliva
Development and validation of a quantitative, non-invasive, highly sensitive and specific, electrochemical assay for anti-SARS-CoV-2 IgG antibodies in saliva Open
Amperial™ is a novel assay platform that uses immobilized antigen in a conducting polymer gel followed by detection via electrochemical measurement of oxidation-reduction reaction between H 2 O 2 /Tetrametylbenzidine and peroxidase enzyme …
View article: Data for figures on Chiang et al.
Data for figures on Chiang et al. Open
Data related to publication on PLOS One by Chiang et al.
View article: Chiang Figures 05_14_2021 Plos.xlsx
Chiang Figures 05_14_2021 Plos.xlsx Open
Data for Plos one publication
View article: Development and validation of a highly sensitive and specific electrochemical assay to quantify anti-SARS-CoV-2 IgG antibodies to facilitate pandemic surveillance and monitoring of vaccine response
Development and validation of a highly sensitive and specific electrochemical assay to quantify anti-SARS-CoV-2 IgG antibodies to facilitate pandemic surveillance and monitoring of vaccine response Open
Amperial™ is a novel assay platform that uses immobilized antigen in a conductive polymer gel followed by an electrochemical detection. A highly specific and sensitive assay was developed to quantify levels of IgG antibodies to SARS-CoV-2 …
View article: A Remote Patient Monitoring System for Congestive Heart Failure
A Remote Patient Monitoring System for Congestive Heart Failure Open
Congestive heart failure (CHF) is a leading cause of death in the United States affecting approximately 670,000 individuals. Due to the prevalence of CHF related issues, it is prudent to seek out methodologies that would facilitate the pre…
View article: Ultra-Short Circulating Tumor DNA (usctDNA) in Plasma and Saliva of Non-Small Cell Lung Cancer (NSCLC) Patients
Ultra-Short Circulating Tumor DNA (usctDNA) in Plasma and Saliva of Non-Small Cell Lung Cancer (NSCLC) Patients Open
Mutations identified in the epidermal growth factor receptor (EGFR) predict sensitivity to EGFR-targeted therapy for non-small cell lung carcinoma (NSCLC). We previously reported that Electric Field-Induced Release and Measurement (EFIRM)-…
View article: Cyber Security Tool Kit (CyberSecTK): A Python Library for Machine Learning and Cyber Security
Cyber Security Tool Kit (CyberSecTK): A Python Library for Machine Learning and Cyber Security Open
The cyber security toolkit, CyberSecTK, is a simple Python library for preprocessing and feature extraction of cyber-security-related data. As the digital universe expands, more and more data need to be processed using automated approaches…
View article: Vorschau: Chem. Ing. Tech. 4/2018
Vorschau: Chem. Ing. Tech. 4/2018 Open
PartikeltechnologiePartikel finden sich in der chemischen Industrie in den unterschiedlichsten Bereichen fu ¨r die verschiedensten Zwecke.Die große Bedeutung dieser Materialien zeigt sich auch an der umfangreichen Forschung auf diesem Gebi…
View article: Saliva Liquid Biopsy for Point-of-Care Applications
Saliva Liquid Biopsy for Point-of-Care Applications Open
Saliva is a non-invasive biofluid, which is easy to collect, transport, and store. Because of its accessibility and connection to systemic diseases, saliva is one of the best candidates for the advancement of point-of-care medicine, where …