Matthias C. Braunisch
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View article: Correction: All eyes on PCS: analysis of the retinal microvasculature in patients with post-COVID syndrome—study protocol of a 1 year prospective case–control study
Correction: All eyes on PCS: analysis of the retinal microvasculature in patients with post-COVID syndrome—study protocol of a 1 year prospective case–control study Open
View article: Long-term prediction of mortality by heart rate turbulence in hemodialysis patients and the impact of diabetes mellitus–a longitudinal observational study
Long-term prediction of mortality by heart rate turbulence in hemodialysis patients and the impact of diabetes mellitus–a longitudinal observational study Open
View article: Estimating Lifetime Risk of Autosomal Recessive Kidney Diseases Using Population-Based Genotypic Data
Estimating Lifetime Risk of Autosomal Recessive Kidney Diseases Using Population-Based Genotypic Data Open
View article: Measures of wave intensity as a non-invasive surrogate for cardiac function predicts mortality in haemodialysis patients
Measures of wave intensity as a non-invasive surrogate for cardiac function predicts mortality in haemodialysis patients Open
Background Risk prediction in haemodialysis (HD) patients is challenging due to the impact of the dialysis regime on the patient's volume status and the complex interplay with cardiac function, comorbidities and hypertension. Cardiac funct…
View article: Endothelial dysfunction in retinal vessels of hemodialysis patients compared to healthy controls
Endothelial dysfunction in retinal vessels of hemodialysis patients compared to healthy controls Open
View article: #1012 Lifetime risk of autosomal recessive kidney diseases calculated from genetic databases
#1012 Lifetime risk of autosomal recessive kidney diseases calculated from genetic databases Open
Background and Aims Genetic kidney diseases represent an often rare and clinically diverse group. Their distinct clinical and genetic variations and biases in patient referrals and identification pose challenges in phenotype-based estimate…
View article: SARS-CoV-2 Neutralization Capacity in Hemodialysis Patients with and without a Fifth Vaccination with the Updated Comirnaty Original/Omicron BA.4-5 Vaccine
SARS-CoV-2 Neutralization Capacity in Hemodialysis Patients with and without a Fifth Vaccination with the Updated Comirnaty Original/Omicron BA.4-5 Vaccine Open
Background: Hemodialysis patients have reduced serologic immunity after SARS-CoV-2 vaccination compared to the general population and an increased risk of morbidity and mortality when exposed to SARS-CoV-2. Methods: Sixty-six hemodialysis …
View article: Potential and Uncertainties of RejectClass in Acute Kidney Graft Dysfunction: An Independent Validation Study
Potential and Uncertainties of RejectClass in Acute Kidney Graft Dysfunction: An Independent Validation Study Open
Background. Kidney graft rejections are classified based on the Banff classification. The RejectClass algorithm, initially derived from a cohort comprising mostly protocol biopsies, identifies data-driven phenotypes of acute rejection and …
View article: Table_Nephropathies_Lifetime risk_Raw data excluded variants.xlsx
Table_Nephropathies_Lifetime risk_Raw data excluded variants.xlsx Open
Raw data to the paper " Lifetime risk of autosomal recessive kidney diseases calculated from genetic databases". All excluded variants, their allele frequencies as listed in our in-house and gnomAD database.
View article: Table_Nephropathies_Lifetime risk_Raw data included variants.xlsx
Table_Nephropathies_Lifetime risk_Raw data included variants.xlsx Open
Raw data to the paper " Lifetime risk of autosomal recessive kidney diseases calculated from genetic databases". All (likely) pathogenic included variants, their allele frequencies as listed in our in-house and gnomAD database.
View article: Extracorporeal light-chain elimination in myeloma with simple medium cutoff membrane hemodialysis: a retrospective cohort study
Extracorporeal light-chain elimination in myeloma with simple medium cutoff membrane hemodialysis: a retrospective cohort study Open
Background We determined the efficacy of free light chain (FLC) removal by regular dialysis equipment (high-flux filtration) with medium cutoff (MCO) membrane hemodialysis (HD) as an adjuvant treatment to standard chemotherapy for patients…
View article: Longitudinal SARS-CoV-2 neutralization of Omicron BA.1, BA.5 and BQ.1.1 after four vaccinations and the impact of breakthrough infections in haemodialysis patients
Longitudinal SARS-CoV-2 neutralization of Omicron BA.1, BA.5 and BQ.1.1 after four vaccinations and the impact of breakthrough infections in haemodialysis patients Open
Background Individuals on haemodialysis (HD) are more vulnerable to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection than the general population due to end-stage kidney disease–induced immunosuppression. Methods A tot…
View article: Automatic ECG-based detection of left ventricular hypertrophy and its predictive value in haemodialysis patients
Automatic ECG-based detection of left ventricular hypertrophy and its predictive value in haemodialysis patients Open
Objective. Left ventricular hypertrophy (LVH) is one of the most severe risk factors in patients with end-stage kidney disease (ESKD) regarding all-cause and cardiovascular mortality. It contributes to the risk of sudden cardiac death whic…
View article: #2599 LONG-TERM LONGITUDINAL CHANGES OF PULSE WAVE VELOCITY AND THEIR ASSOCIATION TO CARDIOVASCULAR RISK FACTORS IN MAINTENANCE HEMODIALYSIS PATIENTS
#2599 LONG-TERM LONGITUDINAL CHANGES OF PULSE WAVE VELOCITY AND THEIR ASSOCIATION TO CARDIOVASCULAR RISK FACTORS IN MAINTENANCE HEMODIALYSIS PATIENTS Open
Background and Aims The incidence of end-stage renal disease (ESRD) is increasing worldwide. The mortality rate in this patient cohort remains unacceptably high. The WHO estimates ESRD as one of the ten global causes of premature death. Ap…
View article: #4876 CLASSIFICATION OF BIOPSY FINDINGS IN INDIVIDUALS WITH NEPHROPATHIES USING MOLECULAR GENETIC TESTING AND PROTEOMICS
#4876 CLASSIFICATION OF BIOPSY FINDINGS IN INDIVIDUALS WITH NEPHROPATHIES USING MOLECULAR GENETIC TESTING AND PROTEOMICS Open
Background and Aims In approximately 10% of adults with chronic kidney disease, a hereditary cause can be identified. Important representatives are Alport syndrome and inherited podocytopathies, which often show the histological picture of…
View article: Locating Medical Information during an Infodemic: Information Seeking Behavior and Strategies of Health-Care Workers in Germany
Locating Medical Information during an Infodemic: Information Seeking Behavior and Strategies of Health-Care Workers in Germany Open
Background: The COVID-19 pandemic has led to a flood of—often contradictory—evidence. HCWs had to develop strategies to locate information that supported their work. We investigated the information-seeking of different HCW groups in German…
View article: Comparable cellular and humoral immunity upon homologous and heterologous COVID-19 vaccination regimens in kidney transplant recipients
Comparable cellular and humoral immunity upon homologous and heterologous COVID-19 vaccination regimens in kidney transplant recipients Open
Background Kidney transplant recipients (KTRs) are at high risk for a severe course of coronavirus disease 2019 (COVID-19); thus, effective vaccination is critical. However, the achievement of protective immunogenicity is hampered by immun…
View article: Longitudinal SARS-CoV-2 neutralization of Omicron BA.1, BA.5 and BQ.1.1 after four vaccinations and the impact of break-through infections in hemodialysis patients
Longitudinal SARS-CoV-2 neutralization of Omicron BA.1, BA.5 and BQ.1.1 after four vaccinations and the impact of break-through infections in hemodialysis patients Open
Background Individuals on hemodialysis are more vulnerable to SARS-CoV-2 infection than the general population due to end-stage kidney disease-induced immunosuppression. Methods 26 hemodialysis patients experiencing SARS-CoV-2 infection af…
View article: Exome sequencing in individuals with congenital anomalies of the kidney and urinary tract (CAKUT): a single-center experience
Exome sequencing in individuals with congenital anomalies of the kidney and urinary tract (CAKUT): a single-center experience Open
Individuals with congenital anomalies of the kidney and urinary tract (CAKUT) show a broad spectrum of malformations. CAKUT can occur in an isolated fashion or as part of a syndromic disorder and can lead to end-stage kidney failure. A mon…
View article: Public information needs and preferences on COVID-19: a cross-sectional study
Public information needs and preferences on COVID-19: a cross-sectional study Open
View article: Lifetime Risk of Autosomal Recessive Kidney Diseases Calculated from Genetic Databases
Lifetime Risk of Autosomal Recessive Kidney Diseases Calculated from Genetic Databases Open
View article: Exome sequencing in individuals with congenital anomalies of the kidney and urinary tract (CAKUT): a single-center experience
Exome sequencing in individuals with congenital anomalies of the kidney and urinary tract (CAKUT): a single-center experience Open
Individuals with congenital anomalies of the kidney and urinary tract (CAKUT) show a broad spectrum of malformations. CAKUT can occur in an isolated fashion or as part of a syndromic disorder and can lead to end-stage kidney failure. A mon…
View article: Renal X-inactivation in female individuals with X-linked Alport syndrome primarily determined by age
Renal X-inactivation in female individuals with X-linked Alport syndrome primarily determined by age Open
X-linked Alport syndrome (AS) caused by hemizygous disease-causing variants in COL4A5 primarily affects males. Females with a heterozygous state show a diverse phenotypic spectrum ranging from microscopic hematuria to end-stage kidney dise…
View article: A randomized prospective cross over study on the effects of medium cut-off membranes on T cellular and serologic immune phenotypes in hemodialysis
A randomized prospective cross over study on the effects of medium cut-off membranes on T cellular and serologic immune phenotypes in hemodialysis Open
View article: The multifaceted phenotypic and genotypic spectrum of type-IV-collagen-related nephropathy—A human genetics department experience
The multifaceted phenotypic and genotypic spectrum of type-IV-collagen-related nephropathy—A human genetics department experience Open
Disease-causing variants in COL4A3- 5 are associated with type-IV-collagen-related nephropathy, a genetically and phenotypically multifaceted disorder comprising Alport syndrome (AS) and thin basement membrane nephropathy (TBMN) and autoso…
View article: Improved SARS-CoV-2 Neutralization of Delta and Omicron BA.1 Variants of Concern after Fourth Vaccination in Hemodialysis Patients
Improved SARS-CoV-2 Neutralization of Delta and Omicron BA.1 Variants of Concern after Fourth Vaccination in Hemodialysis Patients Open
Hemodialysis patients are exposed to a markedly increased risk when infected with SARS-CoV-2. To date, it is unclear if hemodialysis patients benefit from four vaccinations. A total of 142 hemodialysis patients received four COVID-19 vacci…
View article: Improved SARS-CoV-2 neutralization of Delta and Omicron variants of concern after fourth vaccination in hemodialysis patients
Improved SARS-CoV-2 neutralization of Delta and Omicron variants of concern after fourth vaccination in hemodialysis patients Open
Background Hemodialysis patients are exposed to a markedly increased risk when infected with SARS-CoV-2. To date it is unclear if hemodialysis patients benefit from a fourth vaccination. Methods A total of 142 hemodialysis patients (median…
View article: Study protocol: the TRAnsplant BIOpsies (TRABIO) study – a prospective, observational, multicentre cohort study to assess the treatment of kidney graft rejections
Study protocol: the TRAnsplant BIOpsies (TRABIO) study – a prospective, observational, multicentre cohort study to assess the treatment of kidney graft rejections Open
Introduction Despite continued efforts, long-term outcomes of kidney transplantation remain unsatisfactory. Kidney graft rejections are independent risk factors for graft failure. At the participating centres of the TRAnsplant BIOpsies stu…
View article: Identification of risk factors for upper gastrointestinal bleeding in intensive care unit patients (GIBICU study)
Identification of risk factors for upper gastrointestinal bleeding in intensive care unit patients (GIBICU study) Open
Risk stratification for the need for therapeutic endoscopy and prediction of mortality in patients with upper gastrointestinal bleeding (UGIB) can be assessed by several scores. However, current scores are not validated for variceal bleedi…
View article: U-Shaped Association of the Heart Rate Variability Triangular Index and Mortality in Hemodialysis Patients With Atrial Fibrillation
U-Shaped Association of the Heart Rate Variability Triangular Index and Mortality in Hemodialysis Patients With Atrial Fibrillation Open
Background: Atrial fibrillation (AF) is common in hemodialysis patients and contributes to increased mortality. We aimed to examine heart rate variability triangular index (HRVI) in hemodialysis patients with AF as it has recently been rep…