Matthias Eberhard
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View article: Epicardial and pericardial adipose tissue: anatomy, physiology, imaging, segmentation, and treatment effects
Epicardial and pericardial adipose tissue: anatomy, physiology, imaging, segmentation, and treatment effects Open
Epicardial adipose tissue (EAT) and pericardial adipose tissue (PAT) are increasingly recognized as distinct fat depots with implications for cardiovascular disease. This review discusses their anatomical and physiological characteristics,…
View article: Diagnostic performance of coronary CT angiography to diagnose acute spontaneous coronary artery dissection
Diagnostic performance of coronary CT angiography to diagnose acute spontaneous coronary artery dissection Open
Coronary CTA has a poor sensitivity for the diagnosis of SCAD, while specificity is high irrespective of SCAD location. Patients with coronary CTA positive for SCAD might be deferred from ICA after careful consideration and when conservati…
View article: Deep Learning–based Automated Coronary Plaque Quantification
Deep Learning–based Automated Coronary Plaque Quantification Open
Objectives: The aim of this study was to evaluate the feasibility and reproducibility of a novel deep learning (DL)-based coronary plaque quantification tool with automatic case preparation in patients undergoing ultra-high resolution (UHR…
View article: Photon-counting detector computed tomography correlates with invasive electroanatomical mapping for myocardial substrate characterization in patients with structural heart disease
Photon-counting detector computed tomography correlates with invasive electroanatomical mapping for myocardial substrate characterization in patients with structural heart disease Open
Background Characterization of the myocardial substrate by non-invasive imaging has been proven useful to guide invasive 3D electroanatomical mapping (EAM) and catheter ablation (CA) of ventricular arrhythmias (VA) in patients with structu…
View article: Myocardial Late Enhancement With Photon-Counting Detector CT in Spontaneous Coronary Artery Dissection
Myocardial Late Enhancement With Photon-Counting Detector CT in Spontaneous Coronary Artery Dissection Open
Objectives: Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome and myocardial infarction. Accurate diagnosis is crucial for appropriate management. This study aimed to compare late enhancement (LE) ima…
View article: Photon-Counting Chest CT at Radiography-Comparable Dose Levels
Photon-Counting Chest CT at Radiography-Comparable Dose Levels Open
Objectives: The introduction of photon-counting detector computed tomography (PCCT) has allowed for significant dose reductions compared to energy-integrating-detector CT, making it particularly relevant for applications such as lung cance…
View article: Reducing contrast media and radiation dose in CT angiography at low tube voltage: animal study with photon-counting detector CT
Reducing contrast media and radiation dose in CT angiography at low tube voltage: animal study with photon-counting detector CT Open
Background Reducing radiation and contrast media (CM) doses in computed tomography angiography (CTA) is especially relevant for potentially vulnerable populations. Low tube voltage photon-counting detector CT (PCD-CT) offers an improved io…
View article: Coronary angiography with photon-counting detector CT—new options and some critical decisions
Coronary angiography with photon-counting detector CT—new options and some critical decisions Open
The advent of photon-counting detector CT brought up various new interesting possibilities for coronary imaging including different scan modes and various post-processing options. The two main scan modes include spectral data acquisition w…
View article: In Vivo Bone Mineral Density Assessment With Spectral Localizer Radiographs From Photon-Counting Detector CT
In Vivo Bone Mineral Density Assessment With Spectral Localizer Radiographs From Photon-Counting Detector CT Open
Purpose The aim of this study was to determine in a prospective patient study the accuracy of areal bone mineral density (aBMD) measurements with spectral localizer radiographs obtained with a clinical photon-counting detector computed tom…
View article: Relationship Between Myocardial Strain and Extracellular Volume: Exploratory Study in Patients with Severe Aortic Stenosis Undergoing Photon-Counting Detector CT
Relationship Between Myocardial Strain and Extracellular Volume: Exploratory Study in Patients with Severe Aortic Stenosis Undergoing Photon-Counting Detector CT Open
Background/Objectives: Diffuse myocardial fibrosis and altered deformation are relevant prognostic factors in aortic stenosis (AS) patients. The aim of this exploratory study was to investigate the relationship between myocardial strain, a…
View article: Chest Manifestation of Cardiac Disease
Chest Manifestation of Cardiac Disease Open
Non-electrocardiographically (ECG)-gated chest CT is primarily used for lung evaluation but can also reveal critical cardiovascular findings. Significant incidental cardiac findings may include chamber enlargement, cardiac shunts (both int…
View article: Multienergy cardiovascular CT imaging: current state and future
Multienergy cardiovascular CT imaging: current state and future Open
Multienergy cardiovascular CT imaging can be defined as data acquisition at 2 (dual-energy) or multiple X-ray energies. Multienergy cardiovascular CT imaging provides additional qualitative and quantitative information such as material map…
View article: The pericoronary adipose tissue attenuation in CT strongly depends on kernels and iterative reconstructions
The pericoronary adipose tissue attenuation in CT strongly depends on kernels and iterative reconstructions Open
Objectives To investigate the influence of kernels and iterative reconstructions on pericoronary adipose tissue (PCAT) attenuation in coronary CT angiography (CCTA). Materials and methods Twenty otherwise healthy subjects (16 females; medi…
View article: Clinically Relevant Extracardiac Findings at Cardiac Imaging: Insights from the European MR/CT Registry
Clinically Relevant Extracardiac Findings at Cardiac Imaging: Insights from the European MR/CT Registry Open
Purpose To determine the prevalence of clinically relevant extracardiac findings at cardiac CT and MRI examinations from a multicenter, multinational MR/CT registry and the relationship of prevalence with examination indications and patien…
View article: Advanced myocardial characterization and function with cardiac CT
Advanced myocardial characterization and function with cardiac CT Open
Non-invasive imaging with characterization and quantification of the myocardium with computed tomography (CT) became feasible owing to recent technical developments in CT technology. Cardiac CT can serve as an alternative modality when car…
View article: Synthetic hematocrit from virtual non-contrast images for myocardial extracellular volume evaluation with photon-counting detector CT
Synthetic hematocrit from virtual non-contrast images for myocardial extracellular volume evaluation with photon-counting detector CT Open
Objectives To assess the accuracy of a synthetic hematocrit derived from virtual non-contrast (VNC) and virtual non-iodine images (VNI) for myocardial extracellular volume (ECV) computation with photon-counting detector computed tomography…
View article: Predicting mortality after transcatheter aortic valve replacement using preprocedural CT
Predicting mortality after transcatheter aortic valve replacement using preprocedural CT Open
Transcatheter aortic valve replacement (TAVR) is a widely used intervention for patients with severe aortic stenosis. Identifying high-risk patients is crucial due to potential postprocedural complications. Currently, this involves manual …
View article: Multi-Energy Low–Kiloelectron Volt versus Single-Energy Low-Kilovolt Images for Endoleak Detection at CT Angiography of the Aorta
Multi-Energy Low–Kiloelectron Volt versus Single-Energy Low-Kilovolt Images for Endoleak Detection at CT Angiography of the Aorta Open
Purpose To compare image quality, diagnostic performance, and conspicuity between single-energy and multi-energy images for endoleak detection at CT angiography (CTA) after endovascular aortic repair (EVAR). Materials and Methods In this s…
View article: Effect of temporal resolution on calcium scoring: insights from photon-counting detector CT
Effect of temporal resolution on calcium scoring: insights from photon-counting detector CT Open
To intra-individually investigate the variation of coronary artery calcium (CAC), aortic valve calcium (AVC), and mitral annular calcium (MAC) scores and the presence of blur artifacts as a function of temporal resolution in patients under…
View article: Virtual calcium removal in calcified coronary arteries with photon-counting detector CT—first in-vivo experience
Virtual calcium removal in calcified coronary arteries with photon-counting detector CT—first in-vivo experience Open
Purpose To evaluate the feasibility and accuracy of quantification of calcified coronary stenoses using virtual non-calcium (VNCa) images in coronary CT angiography (CCTA) with photon-counting detector (PCD) CT compared with quantitative c…
View article: A Novel Reconstruction Technique to Reduce Stair-Step Artifacts in Sequential Mode Coronary CT Angiography
A Novel Reconstruction Technique to Reduce Stair-Step Artifacts in Sequential Mode Coronary CT Angiography Open
Purpose Prospective electrocardiography-triggering is one of the most commonly used cardiac computed tomography (CT) scan modes but can be susceptible to stair-step artifacts in the transition areas of an acquisition over multiple cardiac …