Matthias Huyghe
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View article: Therapeutic approach against cancer through immunotherapy based on NK cells derived from iPSCs
Therapeutic approach against cancer through immunotherapy based on NK cells derived from iPSCs Open
Les cellules Natural Killer (NK) sont des cellules spécialisées dans l'immunosurveillance, capables de reconnaître et de lyser les cellules transformées ou infectées par des virus. En raison de leurs propriétés biologiques spécifiques, le …
View article: Comparative analysis of iPSC-derived NK cells from two differentiation strategies reveals distinct signatures and cytotoxic activities
Comparative analysis of iPSC-derived NK cells from two differentiation strategies reveals distinct signatures and cytotoxic activities Open
Purpose The ability to generate natural killer (NK) cells from induced pluripotent stem cells (iPSCs) has given rise to new possibilities for the large-scale production of homogeneous immunotherapeutic cellular products and opened new aven…
View article: Enhancing natural killer cells proliferation and cytotoxicity using imidazole-based lipid nanoparticles encapsulating interleukin-2 mRNA
Enhancing natural killer cells proliferation and cytotoxicity using imidazole-based lipid nanoparticles encapsulating interleukin-2 mRNA Open
View article: Chimeric antigen-receptor (CAR) engineered natural killer cells in a chronic myeloid leukemia (CML) blast crisis model
Chimeric antigen-receptor (CAR) engineered natural killer cells in a chronic myeloid leukemia (CML) blast crisis model Open
During the last two decades, the introduction of tyrosine kinase inhibitors (TKIs) to the therapy has changed the natural history of CML but progression into accelerated and blast phase (AP/BP) occurs in 3-5% of cases, especially in patien…