Matthias Steinwachs
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View article: Risk communication strategies in secondary prevention of cardiovascular disease: a systematic review with narrative synthesis
Risk communication strategies in secondary prevention of cardiovascular disease: a systematic review with narrative synthesis Open
Background Various strategies exist in the context of primary prevention to communicate individual cardiovascular (CV) disease (CVD) risk, to increase patient awareness, and to intensify risk factor control(1). For secondary CVD prevention…
View article: Etiology, Classification, Diagnostics, and Conservative Management of Osteochondral Lesions of the Talus. 2023 Recommendations of the Working Group “Clinical Tissue Regeneration” of the German Society of Orthopedics and Traumatology
Etiology, Classification, Diagnostics, and Conservative Management of Osteochondral Lesions of the Talus. 2023 Recommendations of the Working Group “Clinical Tissue Regeneration” of the German Society of Orthopedics and Traumatology Open
The working group, “Clinical Tissue Regeneration” of the German Society of Orthopedics and Traumatology (DGOU) issues this paper to update their guidelines. Methods Peer-reviewed literature was analyzed regarding different topics relevant …
View article: Tibial internal rotation in combined anterior cruciate ligament and high-grade anterolateral ligament injury and its influence on ACL length
Tibial internal rotation in combined anterior cruciate ligament and high-grade anterolateral ligament injury and its influence on ACL length Open
View article: Nonoperative and Operative Soft-Tissue and Cartilage Regeneration and Orthopaedic Biologics of the Knee: An Orthoregeneration Network (ON) Foundation Review
Nonoperative and Operative Soft-Tissue and Cartilage Regeneration and Orthopaedic Biologics of the Knee: An Orthoregeneration Network (ON) Foundation Review Open
View article: Biologic Association Annual Summit: 2020 Report
Biologic Association Annual Summit: 2020 Report Open
Interest and research in biologic approaches for tissue healing are exponentially growing for a variety of musculoskeletal conditions. The recent hype concerning musculoskeletal biological therapies (including viscosupplementation, platele…
View article: Autologous Matrix-Induced Chondrogenesis for Treatment of Focal Cartilage Defects in the Knee: A Follow-up Study
Autologous Matrix-Induced Chondrogenesis for Treatment of Focal Cartilage Defects in the Knee: A Follow-up Study Open
Background: Autologous matrix-induced chondrogenesis (AMIC) is a well-established treatment for full-thickness cartilage defects. Purpose: To evaluate the long-term clinical outcomes of AMIC for the treatment of chondral lesions of the kne…
View article: Systematic Review and Meta-Analysis of the Clinical Evidence on the Use of Autologous Matrix-Induced Chondrogenesis in the Knee
Systematic Review and Meta-Analysis of the Clinical Evidence on the Use of Autologous Matrix-Induced Chondrogenesis in the Knee Open
Objective A systematic review and meta-analysis of Autologous Matrix-Induced Chondrogenesis (AMIC®) outcomes for grade III/IV chondral and osteochondral lesions of the knee treated with Chondro-Gide®. Design Studies with a minimum follow-u…
View article: Characterization of polydactyly chondrocytes and their use in cartilage engineering
Characterization of polydactyly chondrocytes and their use in cartilage engineering Open
View article: Biomimetic sulphated alginate hydrogels suppress IL-1β-induced inflammatory responses in human chondrocytes
Biomimetic sulphated alginate hydrogels suppress IL-1β-induced inflammatory responses in human chondrocytes Open
Loss of articular cartilage from ageing, injury or degenerative disease is commonly associated with inflammation, causing pain and accelerating degradation of the cartilage matrix. Sulphated glycosaminoglycans (GAGs) are involved in the re…
View article: Human chondroprogenitors in alginate-collagen hybrid scaffolds produce stable cartilage<i>in vivo</i>
Human chondroprogenitors in alginate-collagen hybrid scaffolds produce stable cartilage<i>in vivo</i> Open
The goal of this study was to evaluate human epiphyseal chondroprogenitor cells (ECPs) as a potential new cell source for cartilage regeneration. ECPs were compared to human bone marrow stromal cells (MSCs) and human adult articular chondr…
View article: Practical execution of defect preparation prior to surgical cartilage intervention: results from a representative meeting survey among experts
Practical execution of defect preparation prior to surgical cartilage intervention: results from a representative meeting survey among experts Open
View article: Pre-Osteoarthritis
Pre-Osteoarthritis Open
Objective An attempt to define pre-osteoarthritis (OA) versus early OA and definitive osteoarthritis. Methods A group of specialists in the field of cartilage science and treatment was formed to consider the nature of OA onset and its poss…