Matthias Weissinger
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View article: Variability of Metabolic Rate and Distribution Volume Quantification in Whole-Body Parametric PATLAK [18F]-FDG PET/CT—A Prospective Trial in Patients with Lung Cancer
Variability of Metabolic Rate and Distribution Volume Quantification in Whole-Body Parametric PATLAK [18F]-FDG PET/CT—A Prospective Trial in Patients with Lung Cancer Open
Background: The recent introduction of whole-body positron emission tomography/ computed tomography (PET/CT) scanners and multi-bed, multi-time point acquisition technique enable calculating fluorodeoxyglucose (FDG) kinetics in the whole b…
View article: Diagnostic performance of Photon-counting CT angiography in peripheral artery disease compared to DSA as gold standard
Diagnostic performance of Photon-counting CT angiography in peripheral artery disease compared to DSA as gold standard Open
Photon-counting CTA demonstrates high sensitivity and specificity for the detection and diagnosis of stenotic lesions in PAD. PC non-calcium reconstruction does not further increase the accuracy compared to PC CTA.
View article: Additional Value of FDG-PET/MRI Complementary to Sentinel Lymphonodectomy for Minimal Invasive Lymph Node Staging in Patients with Endometrial Cancer: A Prospective Study
Additional Value of FDG-PET/MRI Complementary to Sentinel Lymphonodectomy for Minimal Invasive Lymph Node Staging in Patients with Endometrial Cancer: A Prospective Study Open
Background: Lymph node metastases (LNM) are rare in early-stage endometrial cancer, but a diagnostic systematic lymphadenectomy (LNE) is often performed to achieve reliable N-staging. Therefore, this prospective study aimed to evaluate the…
View article: Dual-Time-Point Posttherapy<sup>177</sup>Lu-PSMA-617 SPECT/CT Describes the Uptake Kinetics of mCRPC Lesions and Prognosticates Patients’ Outcome
Dual-Time-Point Posttherapy<sup>177</sup>Lu-PSMA-617 SPECT/CT Describes the Uptake Kinetics of mCRPC Lesions and Prognosticates Patients’ Outcome Open
177Lu-PSMA-617 is an effective therapeutic option in metastasized castration-resistant prostate cancer (mCRPC). However, some patients progress under treatment. We hypothesized that the tracer kinetics within the metastases may …
View article: Non-invasive estimation of split renal function from routine 68Ga-SSR-PET/CT scans
Non-invasive estimation of split renal function from routine 68Ga-SSR-PET/CT scans Open
Objective Patients with impaired kidney function are at elevated risk for nephrotoxicity and hematotoxicity from peptide receptor radionuclide therapy (PPRT) for advanced neuroendocrine tumors. Somatostatin receptor (SSR)-PET/CT imaging is…
View article: Diagnostic Performance of Dynamic Whole-Body Patlak [18F]FDG-PET/CT in Patients with Indeterminate Lung Lesions and Lymph Nodes
Diagnostic Performance of Dynamic Whole-Body Patlak [18F]FDG-PET/CT in Patients with Indeterminate Lung Lesions and Lymph Nodes Open
Background: Static [18F]FDG-PET/CT is the imaging method of choice for the evaluation of indeterminate lung lesions and NSCLC staging; however, histological confirmation of PET-positive lesions is needed in most cases due to its limited sp…
View article: Whole-Body Magnetic Resonance Imaging (MRI) for Staging Melanoma Patients in Direct Comparison to Computed Tomography (CT): Results from a Prospective Positron Emission Tomography (PET)/CT and PET/MRI Study
Whole-Body Magnetic Resonance Imaging (MRI) for Staging Melanoma Patients in Direct Comparison to Computed Tomography (CT): Results from a Prospective Positron Emission Tomography (PET)/CT and PET/MRI Study Open
Purpose: The consideration of radiation exposure is becoming more important in metastatic melanoma due to improved prognoses. The aim of this prospective study was to investigate the diagnostic performance of whole-body (WB) magnetic reson…
View article: Multiparametric Dual-Time-Point [18F]FDG PET/MRI for Lymph Node Staging in Patients with Untreated FIGO I/II Cervical Carcinoma
Multiparametric Dual-Time-Point [18F]FDG PET/MRI for Lymph Node Staging in Patients with Untreated FIGO I/II Cervical Carcinoma Open
[18F]FDG PET/MRI was shown to have limited sensitivity for N-staging in FIGO I/II cervical carcinoma. Therefore, this prospective study aimed to investigate the additional value of multiparametric dual-time-point PET/MRI and to assess pote…
View article: Multiparametric dual-time-point [18F]FDG-PET/MRI for lymph node staging in patients with untreated FIGO I/II cervical carcinoma
Multiparametric dual-time-point [18F]FDG-PET/MRI for lymph node staging in patients with untreated FIGO I/II cervical carcinoma Open
Purpose:[18F]FDG PET/MRI comes with limited sensitivity for initial detection of lymph node metastases (LNM) in early stage cervical carcinoma. Therefore, the aim of this prospective study was to investigate the additional value…
View article: Lymph Node Staging with a Combined Protocol of <sup>18</sup>F-FDG PET/MRI and Sentinel Node SPECT/CT: A Prospective Study in Patients with FIGO I/II Cervical Carcinoma
Lymph Node Staging with a Combined Protocol of <sup>18</sup>F-FDG PET/MRI and Sentinel Node SPECT/CT: A Prospective Study in Patients with FIGO I/II Cervical Carcinoma Open
Lymph node metastasis (LNM) is present in a minority of patients with early stages of cervical carcinomas. As conventional imaging including PET/CT has shown limited sensitivity, systematic lymphadenectomies are often conducted for staging…
View article: Correlation of C-arm CT acquired parenchymal blood volume (PBV) with 99mTc-macroaggregated albumin (MAA) SPECT/CT for radioembolization work-up
Correlation of C-arm CT acquired parenchymal blood volume (PBV) with 99mTc-macroaggregated albumin (MAA) SPECT/CT for radioembolization work-up Open
Objective SPECT/CT with 99m Tc-macroaggregated albumin (MAA) is generally used for diagnostic work-up prior to transarterial radioembolization (TARE) to exclude shunts and to provide additional information for treatment stratification and …
View article: The Prognostic Value of Quantitative Bone SPECT/CT Before <sup>223</sup>Ra Treatment in Metastatic Castration-Resistant Prostate Cancer
The Prognostic Value of Quantitative Bone SPECT/CT Before <sup>223</sup>Ra Treatment in Metastatic Castration-Resistant Prostate Cancer Open
Radiolabeled bisphosphonates such as 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid (99mTc-DPD) typically show intense uptake in skeletal metastases from metastatic castration-resistant prostate cancer (mCRPC). Ex…
View article: Automated Definition of Skeletal Disease Burden in Metastatic Prostate Carcinoma: A 3D Analysis of SPECT/CT Images
Automated Definition of Skeletal Disease Burden in Metastatic Prostate Carcinoma: A 3D Analysis of SPECT/CT Images Open
To meet the current need for skeletal tumor-load estimation in castration-resistant prostate cancer (CRPC), we developed a novel approach based on adaptive bone segmentation. In this study, we compared the program output with existing esti…
View article: Automated Definition of Skeletal Disease Burden in Metastatic Prostate Carcinoma: A 3D Analysis of SPECT/CT Images
Automated Definition of Skeletal Disease Burden in Metastatic Prostate Carcinoma: A 3D Analysis of SPECT/CT Images Open
To meet the current need for skeletal tumor-load estimation in castration-resistant prostate cancer (CRPC), we developed a novel approach based on adaptive bone segmentation. In this study, we compared the program output with existing esti…
View article: Automated Definition of Skeletal Disease Burden in Metastatic Prostate\n Carcinoma: a 3D analysis of SPECT/CT images
Automated Definition of Skeletal Disease Burden in Metastatic Prostate\n Carcinoma: a 3D analysis of SPECT/CT images Open
To meet the current need for skeletal tumor-load estimation in prostate\ncancer (mCRPC), we developed a novel approach, based on adaptive bone\nsegmentation. In this study, we compared the program output with existing\nestimates and with t…
View article: Tumor Burden and Intraosseous Metabolic Activity as Predictors of Bone Marrow Failure during Radioisotope Therapy in Metastasized Prostate Cancer Patients
Tumor Burden and Intraosseous Metabolic Activity as Predictors of Bone Marrow Failure during Radioisotope Therapy in Metastasized Prostate Cancer Patients Open
Rationale . Radium-223-Dichloride (Ra-223) is an alpha-emitter, used to treat bone metastases. Patients with high metastatic burden and/or with increased trabecular bone uptake could present a higher incidence of hematologic toxicity. We h…
View article: Lymphknoten-Staging des Lungenkarzinoms mit ¹⁸F-FDG-PET/CT : Diagnostische Testleistung von SUV-Schwellenwerten mit modernen PET-Rekonstruktionsalgorithmen bei normal großen und vergrößerten Lymphknoten
Lymphknoten-Staging des Lungenkarzinoms mit ¹⁸F-FDG-PET/CT : Diagnostische Testleistung von SUV-Schwellenwerten mit modernen PET-Rekonstruktionsalgorithmen bei normal großen und vergrößerten Lymphknoten Open