Matthieu Gobin
YOU?
Author Swipe
View article: Deciphering shared molecular dysregulation across Parkinson’s disease variants using a multi-modal network-based data integration and analysis
Deciphering shared molecular dysregulation across Parkinson’s disease variants using a multi-modal network-based data integration and analysis Open
View article: P02.18.B INTEGRATIVE OMICS ANALYSIS OF IDH1 MUTANT GLIOMA PATIENTS REVEALS ALTERATIONS IN BUTYRATE METABOLISM
P02.18.B INTEGRATIVE OMICS ANALYSIS OF IDH1 MUTANT GLIOMA PATIENTS REVEALS ALTERATIONS IN BUTYRATE METABOLISM Open
BACKGROUND Mutations in isocitrate dehydrogenase (IDH) 1 or 2 define glioma classification and determine the biology of these tumors. Although IDH is an essential enzyme in the cellular metabolism, powerful genome-wide analyses focus mostl…
View article: Supplementary Data 3 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications
Supplementary Data 3 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications Open
This document contains Supplementary Table S1, which provides the expression data pertaining to the 27-gene signature and relevant clinical data of the Heidelberg cohort.
View article: Supplementary Data 1 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications
Supplementary Data 1 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications Open
This document details the preliminary differential gene expression analysis carried out using the Köln dataset
View article: Supplementary Data 4 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications
Supplementary Data 4 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications Open
This document contains Supplementary Table S2 and S3. Specifically, Table S2 lists the studied genes and documents their deregulation in GBM samples; Table S3 presents the results of the Cox regression analysis of the factors influencing P…
View article: Supplementary Data 3 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications
Supplementary Data 3 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications Open
This document contains Supplementary Table S1, which provides the expression data pertaining to the 27-gene signature and relevant clinical data of the Heidelberg cohort.
View article: Data from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications
Data from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications Open
Inevitable tumor recurrence and a poor median survival are frustrating reminders of the inefficacy of our current standard of care for patients with newly diagnosed glioblastoma (GBM), which includes surgery followed by radiotherapy and ch…
View article: Supplementary Data 1 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications
Supplementary Data 1 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications Open
This document details the preliminary differential gene expression analysis carried out using the Köln dataset
View article: Supplementary Data 5 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications
Supplementary Data 5 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications Open
This document contains Supplementary Table S4, which regroups the differentially expressed genes identified between the G1 and G3 groups of the Wang dataset and the gene ontology terms associated.
View article: Data from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications
Data from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications Open
Inevitable tumor recurrence and a poor median survival are frustrating reminders of the inefficacy of our current standard of care for patients with newly diagnosed glioblastoma (GBM), which includes surgery followed by radiotherapy and ch…
View article: Supplementary Data 5 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications
Supplementary Data 5 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications Open
This document contains Supplementary Table S4, which regroups the differentially expressed genes identified between the G1 and G3 groups of the Wang dataset and the gene ontology terms associated.
View article: Supplementary Data 2 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications
Supplementary Data 2 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications Open
This document contains Supplementary Figures S1-S6 as well as their Legends. Specifically, Fig. S1: characterization of the 52 gene signature; Fig. S2: Validation of the 27 DNA repair and cell cycle gene signature; Fig. S3: Analysis of the…
View article: Supplementary Data 4 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications
Supplementary Data 4 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications Open
This document contains Supplementary Table S2 and S3. Specifically, Table S2 lists the studied genes and documents their deregulation in GBM samples; Table S3 presents the results of the Cox regression analysis of the factors influencing P…
View article: Supplementary Data 2 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications
Supplementary Data 2 from A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications Open
This document contains Supplementary Figures S1-S6 as well as their Legends. Specifically, Fig. S1: characterization of the 52 gene signature; Fig. S2: Validation of the 27 DNA repair and cell cycle gene signature; Fig. S3: Analysis of the…
View article: A robust protocol for the generation of human midbrain organoids
A robust protocol for the generation of human midbrain organoids Open
View article: Targeted DNA repair gene expression study in Glioblastoma patient biopsies: Clinical impact and characterization of the NEIL3 glycosylase, a novel candidate target for therapy
Targeted DNA repair gene expression study in Glioblastoma patient biopsies: Clinical impact and characterization of the NEIL3 glycosylase, a novel candidate target for therapy Open
View article: A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications
A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications Open
Inevitable tumor recurrence and a poor median survival are frustrating reminders of the inefficacy of our current standard of care for patients with newly diagnosed glioblastoma (GBM), which includes surgery followed by radiotherapy and ch…
View article: Decomposition of transcriptional signals from tumours using independent component analysis
Decomposition of transcriptional signals from tumours using independent component analysis Open
View article: DRES-05. TARGETING DNA REPAIR MECHANISMS IN GLIOBLASTOMA: FROM BASIC MECHANISMS TO PRE-CLINICAL ASPECTS AND PERSONALIZED THERAPY
DRES-05. TARGETING DNA REPAIR MECHANISMS IN GLIOBLASTOMA: FROM BASIC MECHANISMS TO PRE-CLINICAL ASPECTS AND PERSONALIZED THERAPY Open
Despite surgical resection and genotoxic treatment with ionizing radiation and the DNA alkylating agent temozolomide (TMZ), glioblastoma remains a highly lethal cancer, due to the action of DNA repair mechanisms that drive resistance and t…
View article: P01.08 Targeting DNA repair mechanisms in glioblastoma: from basic mechanisms to pre-clinical aspects and personalized therapy
P01.08 Targeting DNA repair mechanisms in glioblastoma: from basic mechanisms to pre-clinical aspects and personalized therapy Open
Introduction:Despite surgical resection and genotoxic treatment with ionizing radiation (IR) and the DNA alkylating agent temozolomide (TMZ), glioblastoma remains one of the most lethal cancers, due in great part to the action of complex D…
View article: DNA repair mechanisms and their clinical impact in glioblastoma
DNA repair mechanisms and their clinical impact in glioblastoma Open
Despite surgical resection and genotoxic treatment with ionizing radiation and the DNA alkylating agent temozolomide, glioblastoma remains one of the most lethal cancers, due in great part to the action of DNA repair mechanisms that drive …