Matthieu Schmidt
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View article: Recommendations for lung ventilation and perfusion assessment with chest electrical impedance tomography in critically ill adult patients: an international evidence-based and expert Delphi consensus study
Recommendations for lung ventilation and perfusion assessment with chest electrical impedance tomography in critically ill adult patients: an international evidence-based and expert Delphi consensus study Open
National High-Level Hospital Clinical Research Funding, National Key Research and Development Program, National Natural Science Foundation of China, Peking Union Medical College Hospital Talent Cultivation Program Category C.
View article: Association between socio-economic status and outcomes among critically ill Covid-19 adult patients in France
Association between socio-economic status and outcomes among critically ill Covid-19 adult patients in France Open
View article: Tidal volume and mortality during extracorporeal membrane oxygenation for acute respiratory distress syndrome: a multicenter observational cohort study
Tidal volume and mortality during extracorporeal membrane oxygenation for acute respiratory distress syndrome: a multicenter observational cohort study Open
Background Approximately half of the patients with acute respiratory distress syndrome (ARDS) receiving extracorporeal membrane oxygenation (ECMO) remain ECMO-dependent beyond 14 days after ECMO initiation. The identification of factors as…
View article: Optimizing Extracorporeal Membrane Oxygenation Gas Exchange: Key Insights for Clinical Management
Optimizing Extracorporeal Membrane Oxygenation Gas Exchange: Key Insights for Clinical Management Open
This review examines the role of extracorporeal membrane oxygenation (ECMO) in the management of severe acute respiratory distress syndrome (ARDS), emphasizing its contribution to lung-protective ventilation through optimizing oxygenation …
View article: Liberal or restrictive transfusion for veno-arterial extracorporeal membrane oxygenation patients: a target trial emulation using the OBLEX study data
Liberal or restrictive transfusion for veno-arterial extracorporeal membrane oxygenation patients: a target trial emulation using the OBLEX study data Open
This target trial emulation study suggests that a liberal transfusion threshold may provide a modest survival benefit during the early course of VA-ECMO, but no benefit afterwards. Prospective studies are needed to confirm these findings, …
View article: Extracorporeal life support for adult patients with ARDS
Extracorporeal life support for adult patients with ARDS Open
View article: Optimum electrical impedance tomography-based PEEP and recruitment-to-inflation ratio in patients with severe ARDS on venovenous ECMO
Optimum electrical impedance tomography-based PEEP and recruitment-to-inflation ratio in patients with severe ARDS on venovenous ECMO Open
The R/I ratio is feasible during ultra-protective ventilation and provides valuable indications for guiding PEEP titration. Specifically, an R/I ratio > 0.34 may help identify patients likely to benefit from further individualized PEEP opt…
View article: Liberal or restrictive transfusion for veno-arterial Extracorporeal Membrane Oxygenation patients: a target trial emulation using the OBLEX study data
Liberal or restrictive transfusion for veno-arterial Extracorporeal Membrane Oxygenation patients: a target trial emulation using the OBLEX study data Open
Background: The optimal transfusion threshold for patients undergoing venoarterial extracorporeal membrane oxygenation (VA-ECMO) remains uncertain. Methods: We used data from OBLEX (ClinicalTrials.gov: NCT03714048), an international, prosp…
View article: Does Levosimendan hasten veno-arterial ECMO weaning? A propensity score matching analysis
Does Levosimendan hasten veno-arterial ECMO weaning? A propensity score matching analysis Open
View article: Anti-RNApol3-Associated myocarditis: an emerging disease linking autoimmunity and infection
Anti-RNApol3-Associated myocarditis: an emerging disease linking autoimmunity and infection Open
View article: Correction: Beta-blockers in refractory hypoxemia on venovenous extracorporeal membrane oxygenation: a double-edged sword
Correction: Beta-blockers in refractory hypoxemia on venovenous extracorporeal membrane oxygenation: a double-edged sword Open
View article: Fever following extracorporeal membrane oxygenation decannulation: Infection, thrombosis or just physiology?
Fever following extracorporeal membrane oxygenation decannulation: Infection, thrombosis or just physiology? Open
Post-decannulation fever was common, and was mainly due to infections or thrombosis. Fever should therefore not be considered as a benign inflammatory reaction until proven otherwise.
View article: Mechanical ventilation settings during weaning from venovenous extracorporeal membrane oxygenation
Mechanical ventilation settings during weaning from venovenous extracorporeal membrane oxygenation Open
View article: Definition and management of right ventricular injury in adult patients receiving extracorporeal membrane oxygenation for respiratory support using the Delphi method: a PRORVnet study. Expert position statements
Definition and management of right ventricular injury in adult patients receiving extracorporeal membrane oxygenation for respiratory support using the Delphi method: a PRORVnet study. Expert position statements Open
View article: Practical considerations on hypoxemia and hypoxia in V-V ECMO patients
Practical considerations on hypoxemia and hypoxia in V-V ECMO patients Open
View article: Recurrent ventilator-associated pneumonia in severe Covid-19 ARDS patients requiring ECMO support
Recurrent ventilator-associated pneumonia in severe Covid-19 ARDS patients requiring ECMO support Open
Objective To describe ventilator-associated pneumonia (VAP) recurrence in COVID-19 patients requiring extracorporeal membrane oxygenation (ECMO) support, and to evaluate the impact of antimicrobial treatment duration of the first VAP episo…
View article: Right ventricular injury definition and management in patients with severe respiratory failure receiving veno-venous extracorporeal membrane oxygenation: a scoping review
Right ventricular injury definition and management in patients with severe respiratory failure receiving veno-venous extracorporeal membrane oxygenation: a scoping review Open
Purpose: Right ventricular (RV) injury in patients with respiratory failure receiving veno-venous extracorporeal membrane oxygenation (VV ECMO) is associated with significant mortality. A consensus on the definition and management of RV in…
View article: Bleeding complications, coagulation disorders, and their management in acute myocardial infarction-related cardiogenic shock rescued by veno-arterial ECMO: A retrospective cohort study
Bleeding complications, coagulation disorders, and their management in acute myocardial infarction-related cardiogenic shock rescued by veno-arterial ECMO: A retrospective cohort study Open
Bleeding complications and coagulation disorders were frequent and severe in patients on VA-ECMO after AMI, leading of antiplatelet therapy withdrawal in one third of patients.
View article: Mechanical ventilation settings during weaning from venovenous extracorporeal membrane oxygenation
Mechanical ventilation settings during weaning from venovenous extracorporeal membrane oxygenation Open
Objectives: To describe clinical characteristics, mechanical ventilation strategies, and outcomes in patients with severe acute respiratory distress syndrome (ARDS) during weaning from venovenous extracorporeal membrane oxygenation (VV ECM…
View article: Healthcare-associated infections in patients with severe COVID-19 supported with extracorporeal membrane oxygenation: a nationwide cohort study
Healthcare-associated infections in patients with severe COVID-19 supported with extracorporeal membrane oxygenation: a nationwide cohort study Open
View article: Reply to Wendel-Garcia <i>et al</i>.: Low-Dose Anticoagulation to Prevent Intracranial Hemorrhage in COVID-19 Patients under Extracorporeal Membrane Oxygenation Support
Reply to Wendel-Garcia <i>et al</i>.: Low-Dose Anticoagulation to Prevent Intracranial Hemorrhage in COVID-19 Patients under Extracorporeal Membrane Oxygenation Support Open
View article: Authors reply in response to a letter on: “Diagnostic yield, safety and therapeutic consequences of myocardial biopsy in clinically suspected fulminant myocarditis unweanable from mechanical circulatory support”
Authors reply in response to a letter on: “Diagnostic yield, safety and therapeutic consequences of myocardial biopsy in clinically suspected fulminant myocarditis unweanable from mechanical circulatory support” Open
View article: Survival and Long-Term Functional Status of COVID-19 Patients Requiring Prolonged Extracorporeal Membrane Oxygenation Support
Survival and Long-Term Functional Status of COVID-19 Patients Requiring Prolonged Extracorporeal Membrane Oxygenation Support Open
Rationale: Severe cases of acute respiratory distress syndrome (ARDS) may require prolonged (>28 d) extracorporeal membrane oxygenation (ECMO). In nonresolving disease, recovery is uncertain, and lung transplant may be proposed. …
View article: Electrical Impedance Tomography to Monitor Hypoxemic Respiratory Failure
Electrical Impedance Tomography to Monitor Hypoxemic Respiratory Failure Open
Hypoxemic respiratory failure is one of the leading causes of mortality in intensive care. Frequent assessment of individual physiological characteristics and delivery of personalized mechanical ventilation (MV) settings is a constant chal…
View article: Prone Positioning During Extracorporeal Membrane Oxygenation in Patients With Severe ARDS
Prone Positioning During Extracorporeal Membrane Oxygenation in Patients With Severe ARDS Open
Importance Prone positioning may improve outcomes in patients with severe acute respiratory distress syndrome (ARDS), but it is unknown whether prone positioning improves clinical outcomes among patients with ARDS who are undergoing venove…
View article: Reply to: Candidacy for Extracorporeal Membrane Oxygenation Should Start with Ventilatory Support Optimization
Reply to: Candidacy for Extracorporeal Membrane Oxygenation Should Start with Ventilatory Support Optimization Open
"Reply to: Candidacy for ECMO Should Start with Ventilatory Support Optimization." American Journal of Respiratory and Critical Care Medicine, 0(ja), pp.
View article: Fulminant myocarditis proven by early biopsy and outcomes
Fulminant myocarditis proven by early biopsy and outcomes Open
Background and Aims While endomyocardial biopsy (EMB) is recommended in adult patients with fulminant myocarditis, the clinical impact of its timing is still unclear. Methods Data were collected from 419 adult patients with clinically susp…
View article: Diaphragm function in patients with Covid-19-related acute respiratory distress syndrome on venovenous extracorporeal membrane oxygenation
Diaphragm function in patients with Covid-19-related acute respiratory distress syndrome on venovenous extracorporeal membrane oxygenation Open
Background Venovenous extracorporeal membrane oxygenation (VV ECMO) is frequently associated with deep sedation and neuromuscular blockades, that may lead to diaphragm dysfunction. However, the prevalence, risk factors, and evolution of di…
View article: Beta-blockers in refractory hypoxemia on venovenous extracorporeal membrane oxygenation: a double-edged sword
Beta-blockers in refractory hypoxemia on venovenous extracorporeal membrane oxygenation: a double-edged sword Open
View article: Diagnostic yield, safety and therapeutic consequences of myocardial biopsy in clinically suspected fulminant myocarditis unweanable from mechanical circulatory support
Diagnostic yield, safety and therapeutic consequences of myocardial biopsy in clinically suspected fulminant myocarditis unweanable from mechanical circulatory support Open
Background Fulminant myocarditis is a rare and severe disease whose definite and etiological diagnoses rely on pathological examination. Albeit, myocardial biopsy can be associated with significant morbidity and mortality, its therapeutic …