Matti Lehtinen
YOU?
Author Swipe
View article: Induced abortion rates among women vaccinated against human papillomavirus: Registry-based follow-up of a community-randomized trial
Induced abortion rates among women vaccinated against human papillomavirus: Registry-based follow-up of a community-randomized trial Open
HPV-vaccinated had lower induced abortion rates than unvaccinated individuals. When further developing HPV-vaccination programs, simultaneous sexual health education should be considered to comprehensively improve the reproductive health o…
View article: Human papillomavirus vaccinations’ impact on preterm birth rates
Human papillomavirus vaccinations’ impact on preterm birth rates Open
Removal of human papillomavirus (HPV) infection associated precancerous cervical lesions by conization is one of the most important causes of preterm birth. Prophylactic HPV-vaccinations can prevent these lesions and reduce the need of the…
View article: Controlled trial of cervical cancer screening frequency among human‐papillomavirus‐vaccinated women
Controlled trial of cervical cancer screening frequency among human‐papillomavirus‐vaccinated women Open
Cervical screening frequency has not been studied in vaccinees. As the major risk factor, oncogenic human papillomavirus (HPV) is declining due to vaccination. We report a trial to assess the effectiveness of cervical screening frequency a…
View article: Elevated Risk of <scp>HPV</scp>‐Associated Oropharyngeal Cancers in Husbands of Women With Anogenital Cancer
Elevated Risk of <span>HPV</span>‐Associated Oropharyngeal Cancers in Husbands of Women With Anogenital Cancer Open
Introduction Human papillomavirus (HPV) infection is associated with tonsillar and base‐of‐tongue squamous cell carcinomas (TSCC/BOTSCC). We evaluated the relative risk (RR) of TSCC/BOTSCC in the husbands of women with anogenital cancer us…
View article: The prevalence of nine human herpesviruses in urogenital samples from young women in Finland
The prevalence of nine human herpesviruses in urogenital samples from young women in Finland Open
View article: Scientific approaches to defining <scp>HPV</scp> vaccine‐induced protective immunity
Scientific approaches to defining <span>HPV</span> vaccine‐induced protective immunity Open
Seventeen years after the licensure of prophylactic human papillomavirus (HPV) L1 virus‐like‐particle vaccines, a defined antibody level that correlates with vaccine‐induced protection against HPV infections and associated neoplasia is mis…
View article: Elimination of cervical cancer by refined vaccination and screening
Elimination of cervical cancer by refined vaccination and screening Open
View article: Head-to-head comparison of two human papillomavirus vaccines for efficacy against cervical intraepithelial neoplasia grade 3 and adenocarcinoma in situ—population-based follow-up of two cluster-randomized trials
Head-to-head comparison of two human papillomavirus vaccines for efficacy against cervical intraepithelial neoplasia grade 3 and adenocarcinoma in situ—population-based follow-up of two cluster-randomized trials Open
Introduction We report head-to-head comparison of the bivalent and quadrivalent HPV vaccine efficacies against immediate precursors of cervical cancer from 15 years’ country-wide cancer registry follow-up of phase III trial cohorts and an …
View article: Lack of detectable HPV18 antibodies in 14% of quadrivalent vaccinees in a longitudinal cohort study
Lack of detectable HPV18 antibodies in 14% of quadrivalent vaccinees in a longitudinal cohort study Open
View article: Seroepidemiological assessment of the spread of SARS-CoV-2 among 25 and 28 year-old adult women in Finland between March 2020-June 2022
Seroepidemiological assessment of the spread of SARS-CoV-2 among 25 and 28 year-old adult women in Finland between March 2020-June 2022 Open
Introduction Serological surveys of the prevalence of SARS-CoV-2 are instrumental to understanding the course of the COVID-19 epidemic. We evaluate the seroprevalence of SARS-CoV-2 among young adult Finnish females residing in 25 communiti…
View article: Low methylation marker levels among human papillomavirus‐vaccinated women with cervical high‐grade squamous intraepithelial lesions
Low methylation marker levels among human papillomavirus‐vaccinated women with cervical high‐grade squamous intraepithelial lesions Open
Cervical cancer screening programs, including triage tests, need redesigning as human papillomavirus (HPV)‐vaccinated women are entering the programs. Methylation markers offer a potential solution to reduce false‐positive rates by identif…
View article: The quality of life of frequently vs. infrequently screened HPV vaccinated women
The quality of life of frequently vs. infrequently screened HPV vaccinated women Open
Purpose Cervical lesions caused by human papillomavirus (HPV) are related to decreased quality of life (QoL) of women. Also, cervical cancer (CC) screening can cause psychological adverse effects. It has been assumed that by decreasing the…
View article: Scientific approaches toward improving cervical cancer elimination strategies
Scientific approaches toward improving cervical cancer elimination strategies Open
At the 2023 EUROGIN workshop scientific basis for strategies to accelerate the elimination of cervical cancer and its causative agent, human papillomavirus (HPV) were reviewed. Although some countries have reached key performance indicator…
View article: Ecological diversity profiles of non-vaccine-targeted HPVs after gender-based community vaccination efforts
Ecological diversity profiles of non-vaccine-targeted HPVs after gender-based community vaccination efforts Open
The long-term effect of population-level human papillomavirus (HPV) vaccination on the viral ecology of the untargeted HPVs is poorly understood. We performed an 8-year follow-up of 33 communities randomized to gender-neutral HPV16/18 vacc…
View article: Supplementary Tables 1-2 from A Pooled Analysis of Continued Prophylactic Efficacy of Quadrivalent Human Papillomavirus (Types 6/11/16/18) Vaccine against High-grade Cervical and External Genital Lesions
Supplementary Tables 1-2 from A Pooled Analysis of Continued Prophylactic Efficacy of Quadrivalent Human Papillomavirus (Types 6/11/16/18) Vaccine against High-grade Cervical and External Genital Lesions Open
PDF file - 284K
View article: Data from A Pooled Analysis of Continued Prophylactic Efficacy of Quadrivalent Human Papillomavirus (Types 6/11/16/18) Vaccine against High-grade Cervical and External Genital Lesions
Data from A Pooled Analysis of Continued Prophylactic Efficacy of Quadrivalent Human Papillomavirus (Types 6/11/16/18) Vaccine against High-grade Cervical and External Genital Lesions Open
Quadrivalent human papillomavirus (HPV) vaccine has been shown to provide protection from HPV 6/11/16/18–related cervical, vaginal, and vulvar disease through 3 years. We provide an update on the efficacy of the quadrivalent HPV vaccine ag…
View article: Data from A Pooled Analysis of Continued Prophylactic Efficacy of Quadrivalent Human Papillomavirus (Types 6/11/16/18) Vaccine against High-grade Cervical and External Genital Lesions
Data from A Pooled Analysis of Continued Prophylactic Efficacy of Quadrivalent Human Papillomavirus (Types 6/11/16/18) Vaccine against High-grade Cervical and External Genital Lesions Open
Quadrivalent human papillomavirus (HPV) vaccine has been shown to provide protection from HPV 6/11/16/18–related cervical, vaginal, and vulvar disease through 3 years. We provide an update on the efficacy of the quadrivalent HPV vaccine ag…
View article: Supplementary Tables 1-2 from A Pooled Analysis of Continued Prophylactic Efficacy of Quadrivalent Human Papillomavirus (Types 6/11/16/18) Vaccine against High-grade Cervical and External Genital Lesions
Supplementary Tables 1-2 from A Pooled Analysis of Continued Prophylactic Efficacy of Quadrivalent Human Papillomavirus (Types 6/11/16/18) Vaccine against High-grade Cervical and External Genital Lesions Open
PDF file - 284K
View article: Supplementary Methods from Androgens Are Differentially Associated with Ovarian Cancer Subtypes in the Ovarian Cancer Cohort Consortium
Supplementary Methods from Androgens Are Differentially Associated with Ovarian Cancer Subtypes in the Ovarian Cancer Cohort Consortium Open
Supplementary methods files describes the participating cohorts, study population, and statistical methods in detail.
View article: Supplementary Tables S1-S5, Figure S1 from Androgens Are Differentially Associated with Ovarian Cancer Subtypes in the Ovarian Cancer Cohort Consortium
Supplementary Tables S1-S5, Figure S1 from Androgens Are Differentially Associated with Ovarian Cancer Subtypes in the Ovarian Cancer Cohort Consortium Open
Supplementary Table S1 provides details on each of the participating studies, including recruitment period, fasting status at blood collection and storage temperature of blood specimens, number of matched controls per case, and the matchin…
View article: Supplementary Tables S1-S5, Figure S1 from Androgens Are Differentially Associated with Ovarian Cancer Subtypes in the Ovarian Cancer Cohort Consortium
Supplementary Tables S1-S5, Figure S1 from Androgens Are Differentially Associated with Ovarian Cancer Subtypes in the Ovarian Cancer Cohort Consortium Open
Supplementary Table S1 provides details on each of the participating studies, including recruitment period, fasting status at blood collection and storage temperature of blood specimens, number of matched controls per case, and the matchin…
View article: Data from Human Chorionic Gonadotropin Does Not Correlate with Risk for Maternal Breast Cancer: Results from the Finnish Maternity Cohort
Data from Human Chorionic Gonadotropin Does Not Correlate with Risk for Maternal Breast Cancer: Results from the Finnish Maternity Cohort Open
Human chorionic gonadotropin (hCG) is necessary for the maintenance of early pregnancy and promotes normal breast cell differentiation. Administered hCG reduces risk of carcinogen-induced breast cancer in animal models, and higher circulat…
View article: Supplementary Methods from Androgens Are Differentially Associated with Ovarian Cancer Subtypes in the Ovarian Cancer Cohort Consortium
Supplementary Methods from Androgens Are Differentially Associated with Ovarian Cancer Subtypes in the Ovarian Cancer Cohort Consortium Open
Supplementary methods files describes the participating cohorts, study population, and statistical methods in detail.
View article: Data from Androgens Are Differentially Associated with Ovarian Cancer Subtypes in the Ovarian Cancer Cohort Consortium
Data from Androgens Are Differentially Associated with Ovarian Cancer Subtypes in the Ovarian Cancer Cohort Consortium Open
Invasive epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy. The etiology of EOC remains elusive; however, experimental and epidemiologic data suggest a role for hormone-related exposures in ovarian carcinogenesis an…
View article: Data from Androgens Are Differentially Associated with Ovarian Cancer Subtypes in the Ovarian Cancer Cohort Consortium
Data from Androgens Are Differentially Associated with Ovarian Cancer Subtypes in the Ovarian Cancer Cohort Consortium Open
Invasive epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy. The etiology of EOC remains elusive; however, experimental and epidemiologic data suggest a role for hormone-related exposures in ovarian carcinogenesis an…
View article: Supplemental Table 1 from Human Chorionic Gonadotropin Does Not Correlate with Risk for Maternal Breast Cancer: Results from the Finnish Maternity Cohort
Supplemental Table 1 from Human Chorionic Gonadotropin Does Not Correlate with Risk for Maternal Breast Cancer: Results from the Finnish Maternity Cohort Open
Supplemental Table 1. Distribution of Covariates by hCG Quartiles: Finnish Maternity Cohort
View article: Supplemental Table 1 from Human Chorionic Gonadotropin Does Not Correlate with Risk for Maternal Breast Cancer: Results from the Finnish Maternity Cohort
Supplemental Table 1 from Human Chorionic Gonadotropin Does Not Correlate with Risk for Maternal Breast Cancer: Results from the Finnish Maternity Cohort Open
Supplemental Table 1. Distribution of Covariates by hCG Quartiles: Finnish Maternity Cohort
View article: Data from Human Chorionic Gonadotropin Does Not Correlate with Risk for Maternal Breast Cancer: Results from the Finnish Maternity Cohort
Data from Human Chorionic Gonadotropin Does Not Correlate with Risk for Maternal Breast Cancer: Results from the Finnish Maternity Cohort Open
Human chorionic gonadotropin (hCG) is necessary for the maintenance of early pregnancy and promotes normal breast cell differentiation. Administered hCG reduces risk of carcinogen-induced breast cancer in animal models, and higher circulat…
View article: Supplemental Table from Early Pregnancy Sex Steroids and Maternal Breast Cancer: A Nested Case–Control Study
Supplemental Table from Early Pregnancy Sex Steroids and Maternal Breast Cancer: A Nested Case–Control Study Open
Doubling of Circulating Endogenous Hormones and Breast Cancer Risk, by Time Between First Birth and Diagnosis and Age at Diagnosis: Finnish Maternity Cohort (n=3,480).
View article: Supplemental Table from Early Pregnancy Sex Steroids and Maternal Breast Cancer: A Nested Case–Control Study
Supplemental Table from Early Pregnancy Sex Steroids and Maternal Breast Cancer: A Nested Case–Control Study Open
Doubling of Circulating Endogenous Hormones and Breast Cancer Risk, by Time Between First Birth and Diagnosis and Age at Diagnosis: Finnish Maternity Cohort (n=3,480).