Maurice Hayot
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View article: Predictors of and reasons for refusal to participate in a digitally supported remote maintenance pulmonary rehabilitation programme
Predictors of and reasons for refusal to participate in a digitally supported remote maintenance pulmonary rehabilitation programme Open
Objective: The study aimed to assess the predictors and the reasons for refusal to participate in a digitally supported remote maintenance pulmonary rehabilitation programme (M-PRP). Methods: Patients contacted to integrate a 12-month M-PR…
View article: Cardiac Fatigue in Male Athletes with Exercise-Induced Pulmonary Impairments After a Very Long-Distance Triathlon
Cardiac Fatigue in Male Athletes with Exercise-Induced Pulmonary Impairments After a Very Long-Distance Triathlon Open
View article: Beyond sarcopenia: frailty in chronic haemodialysis patients
Beyond sarcopenia: frailty in chronic haemodialysis patients Open
Background Frailty, characterized by vulnerability, reduced reserves and increased susceptibility to severe events, is a significant concern in chronic haemodialysis (HD) patients. Sarcopenia, corresponding to the progressive loss of muscl…
View article: Determinants of physical activity in newly diagnosed obstructive sleep apnea patients: testing the health action process approach
Determinants of physical activity in newly diagnosed obstructive sleep apnea patients: testing the health action process approach Open
View article: Quality Assessment of Smartphone Medication Management Apps in France: Systematic Search
Quality Assessment of Smartphone Medication Management Apps in France: Systematic Search Open
Background Adherence to medication is estimated to be around 50% for chronically ill patients in high-income countries. Improving the effectiveness of adherence interventions could have a far greater impact on population health than any im…
View article: Quality Assessment of Smartphone Medication Management Apps in France: Systematic Search (Preprint)
Quality Assessment of Smartphone Medication Management Apps in France: Systematic Search (Preprint) Open
BACKGROUND Adherence to medication is estimated to be around 50% for chronically ill patients in high-income countries. Improving the effectiveness of adherence interventions could have a far greater impact on population health than any i…
View article: Semi-formal and formal specification of a telerehabilitation system for chronic respiratory diseases: methodology and feedback
Semi-formal and formal specification of a telerehabilitation system for chronic respiratory diseases: methodology and feedback Open
International audience
View article: La définition de l’obstruction bronchique par le rapport VEMS/CV : seuil fixe ou limite inférieure de la normale ?
La définition de l’obstruction bronchique par le rapport VEMS/CV : seuil fixe ou limite inférieure de la normale ? Open
View article: Formal verification of a telerehabilitation system through an abstraction and refinement approach using <scp>Uppaal</scp>
Formal verification of a telerehabilitation system through an abstraction and refinement approach using <span>Uppaal</span> Open
Formal methods are proven techniques that provide a rigorous mathematical basis to software development. In particular, they allow the quality of development to be effectively improved by making accurate and explicit modelling, so that ano…
View article: Main Pathogenic Mechanisms and Recent Advances in COPD Peripheral Skeletal Muscle Wasting
Main Pathogenic Mechanisms and Recent Advances in COPD Peripheral Skeletal Muscle Wasting Open
Chronic obstructive pulmonary disease (COPD) is a worldwide prevalent respiratory disease mainly caused by tobacco smoke exposure. COPD is now considered as a systemic disease with several comorbidities. Among them, skeletal muscle dysfunc…
View article: Cellular interplay in skeletal muscle regeneration and wasting: insights from animal models
Cellular interplay in skeletal muscle regeneration and wasting: insights from animal models Open
Skeletal muscle wasting, whether related to physiological ageing, muscle disuse or to an underlying chronic disease, is a key determinant to quality of life and mortality. However, cellular basis responsible for increased catabolism in myo…
View article: Mid-Term Sequelae of Surviving Patients Hospitalized in Intensive Care Unit for COVID-19 Infection: The REHCOVER Study
Mid-Term Sequelae of Surviving Patients Hospitalized in Intensive Care Unit for COVID-19 Infection: The REHCOVER Study Open
Objectives: The objective of this prospective, single-center study was to explore the mid-term outcomes 6 to 9 months after hospitalization in an Intensive Care Unit (ICU) for severe COVID-19 infection. Methods: Patients systematically und…
View article: An individualized mobile health intervention to promote physical activity in adults with obstructive sleep apnea: An intervention mapping approach
An individualized mobile health intervention to promote physical activity in adults with obstructive sleep apnea: An intervention mapping approach Open
Objective Combining continuous positive airway pressure with physical activity (PA) might be a promising strategy to treat obstructive sleep apnea (OSA). This article describes how intervention mapping (IM) can guide the development, conte…
View article: Impact of a telerehabilitation programme combined with continuous positive airway pressure on symptoms and cardiometabolic risk factors in obstructive sleep apnea patients
Impact of a telerehabilitation programme combined with continuous positive airway pressure on symptoms and cardiometabolic risk factors in obstructive sleep apnea patients Open
Background Obstructive sleep apnea syndrome is a common sleep-breathing disorder associated with adverse health outcomes including excessive daytime sleepiness, impaired quality of life and is well-established as a cardiovascular risk fact…
View article: Efficacy of 12 weeks oral beta‐alanine supplementation in patients with chronic obstructive pulmonary disease: a double‐blind, randomized, placebo‐controlled trial
Efficacy of 12 weeks oral beta‐alanine supplementation in patients with chronic obstructive pulmonary disease: a double‐blind, randomized, placebo‐controlled trial Open
Background Beta‐alanine (BA) supplementation increases muscle carnosine, an abundant endogenous antioxidant and pH buffer in skeletal muscle. Carnosine loading promotes exercise capacity in healthy older adults. As patients with chronic ob…
View article: Devenir des patients hospitalisés en soins critiques pour infection à SARS-COV2 : évaluation standardisée des séquelles à 6–9 mois
Devenir des patients hospitalisés en soins critiques pour infection à SARS-COV2 : évaluation standardisée des séquelles à 6–9 mois Open
View article: Standardization of the assessment process within telerehabilitation in chronic diseases: A scoping meta-review
Standardization of the assessment process within telerehabilitation in chronic diseases: A scoping meta-review Open
Background Telerehabilitation (TR) interventions are receiving increasing attention. They have been evaluated in various scientific areas through systematic reviews. However, there is a lack of data on how to standardize assessment and rep…
View article: Double gas transfer factors (DLCO-DLNO) at rest in patients with congenital heart diseases correlates with their ventilatory response during maximal exercise
Double gas transfer factors (DLCO-DLNO) at rest in patients with congenital heart diseases correlates with their ventilatory response during maximal exercise Open
CHD patients with impaired pulmonary circulation have a reduced Dm and Vcap mainly due to decreased pulmonary volume but maintain a normal capacity to adapt these parameters through a simple recruitment manoeuver. Vcap adaptation evaluated…
View article: Mise au point sur la téléréadaptation respiratoire dans la BPCO
Mise au point sur la téléréadaptation respiratoire dans la BPCO Open
View article: Changes in determinants of physical activity during interventions for adults with chronic diseases: systematic review and meta-analysis of randomised controlled trials
Changes in determinants of physical activity during interventions for adults with chronic diseases: systematic review and meta-analysis of randomised controlled trials Open
A better understanding of how interventions can increase the determinants of physical activity in adults with chronic diseases is needed to improve their efficacy. The present meta-analysis aims to assess the efficacy of behaviour change i…
View article: Response to Electrostimulation Is Impaired in Muscle Cells from Patients with Chronic Obstructive Pulmonary Disease
Response to Electrostimulation Is Impaired in Muscle Cells from Patients with Chronic Obstructive Pulmonary Disease Open
Among the comorbidities associated with chronic obstructive pulmonary disease (COPD), skeletal muscle weakness and atrophy are known to affect patient survival rate. In addition to muscle deconditioning, various systemic and intrinsic fact…
View article: Skeletal Muscle Phenotype in Patients Undergoing Long-Term Hemodialysis Awaiting Kidney Transplantation
Skeletal Muscle Phenotype in Patients Undergoing Long-Term Hemodialysis Awaiting Kidney Transplantation Open
Background and objectives Age and comorbidity-related sarcopenia represent a main cause of muscle dysfunction in patients on long-term hemodialysis. However, recent findings suggest muscle abnormalities that are not associated with sarcope…
View article: Impact of a Mobile Telerehabilitation Solution on Metabolic Health Outcomes and Rehabilitation Adherence in Patients With Obesity: Randomized Controlled Trial
Impact of a Mobile Telerehabilitation Solution on Metabolic Health Outcomes and Rehabilitation Adherence in Patients With Obesity: Randomized Controlled Trial Open
Background Obesity is a major public health issue. Combining exercise training, nutrition, and therapeutic education in metabolic rehabilitation (MR) is recommended for obesity management. However, evidence from randomized controlled studi…
View article: Carnosine, oxidative and carbonyl stress, antioxidants, and muscle fiber characteristics of quadriceps muscle of patients with COPD
Carnosine, oxidative and carbonyl stress, antioxidants, and muscle fiber characteristics of quadriceps muscle of patients with COPD Open
Carnosine, particularly present in fast-twitch fibers, was investigated in the quadriceps of patients with chronic obstructive pulmonary disease (COPD). Carnosine concentration was similar between patients with COPD and healthy controls bu…
View article: Telerehabilitation assessment domains and process in chronic diseases: a scoping meta-review
Telerehabilitation assessment domains and process in chronic diseases: a scoping meta-review Open
Background Telerehabilitation (TR) interventions are receiving increasing attention. They have been evaluated in various scientific areas through systematic reviews. However, there is a lack of data on how to standardize assessment and rep…
View article: Efficacy of a long-term pulmonary rehabilitation maintenance program for COPD patients in a real-life setting: a 5-year cohort study
Efficacy of a long-term pulmonary rehabilitation maintenance program for COPD patients in a real-life setting: a 5-year cohort study Open
Background Pulmonary rehabilitation (PR) improves exercise capacity, health-related quality of life (HRQoL) and dyspnea in chronic obstructive pulmonary disease (COPD) patients. Maintenance programs can sustain the benefits for 12 to 24 mo…
View article: Hypoxic Conditions Promote Rhythmic Contractile Oscillations Mediated by Voltage-Gated Sodium Channels Activation in Human Arteries
Hypoxic Conditions Promote Rhythmic Contractile Oscillations Mediated by Voltage-Gated Sodium Channels Activation in Human Arteries Open
Arterial smooth muscle exhibits rhythmic oscillatory contractions called vasomotion and believed to be a protective mechanism against tissue hypoperfusion or hypoxia. Oscillations of vascular tone depend on voltage and follow oscillations …
View article: Impact of a Mobile Telerehabilitation Solution on Metabolic Health Outcomes and Rehabilitation Adherence in Patients With Obesity: Randomized Controlled Trial (Preprint)
Impact of a Mobile Telerehabilitation Solution on Metabolic Health Outcomes and Rehabilitation Adherence in Patients With Obesity: Randomized Controlled Trial (Preprint) Open
BACKGROUND Obesity is a major public health issue. Combining exercise training, nutrition, and therapeutic education in metabolic rehabilitation (MR) is recommended for obesity management. However, evidence from randomized controlled stud…
View article: Dynapaenia and sarcopaenia in chronic haemodialysis patients: do muscle weakness and atrophy similarly influence poor outcome?
Dynapaenia and sarcopaenia in chronic haemodialysis patients: do muscle weakness and atrophy similarly influence poor outcome? Open
Background Sarcopaenia, defined as a decline in both muscle mass and function, has been recognized as a major determinant of poor outcome in haemodialysis (HD) patients. It is generally assumed that sarcopaenia is driven by muscle atrophy …
View article: COPD is deleterious for pericytes: implications during training-induced angiogenesis in skeletal muscle
COPD is deleterious for pericytes: implications during training-induced angiogenesis in skeletal muscle Open
This work confirms the previously reported impairment in the functional response to exercise training of patients with COPD compared with SHS. Moreover, it shows for the first time that pericyte coverage of the skeletal capillaries is dras…