Michael R. O’Connell
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View article: Scoping review of methodology for aiding generalisability and transportability of clinical prediction models
Scoping review of methodology for aiding generalisability and transportability of clinical prediction models Open
Generalisability and transportability of clinical prediction models (CPMs) refer to their ability to maintain predictive performance when applied to new populations. While CPMs may show good generalisability or transportability to a specif…
View article: Acute pancreatitis precedes chronic pancreatitis in the majority of patients: Results from the NAPS2 consortium
Acute pancreatitis precedes chronic pancreatitis in the majority of patients: Results from the NAPS2 consortium Open
View article: The Common Chymotrypsinogen C ( CTRC ) Variant G60G (C.180T) Increases Risk of Chronic Pancreatitis But Not Recurrent Acute Pancreatitis in a North American Population
The Common Chymotrypsinogen C ( CTRC ) Variant G60G (C.180T) Increases Risk of Chronic Pancreatitis But Not Recurrent Acute Pancreatitis in a North American Population Open
The common CTRC variant c.180T acts as disease modifier that promotes progression from RAP to CP, especially in patients with CFTR or SPINK1 variants, alcohol, or smoking.