Explanipedia

People With Lowest Physical Functioning Scores Showed Greatest Improvement After Tirzepatide Treatment Open

Xuan Li, Dachuang Cao, Hélène Sapin, Fangyu Wang, Theresa Hunter , et al. · 2025

Objective This post hoc analysis of SURMOUNT trials assessed the association of baseline physical function (PF) with obesity‐related complications (ORCs), efficacy measures, and PF. The mechanism of tirzepatide‐led improvements in PF was e…

Understanding the clinical characteristics associated with health care costs and cost savings upon weight reduction in individuals with obesity or overweight Open

Xuan Li, Carlos Vallarino, Max Denning, Theresa Hunter, David Schapiro , et al. · 2025

Aims This study aimed to (1) identify characteristics of people with obesity or overweight that are predictive of health care costs; and (2) identify potential subgroups associated with weight reduction and cost savings following weight re…

Comparing Prehospital Time Among Pediatric Poisoning Patients in Rural and Urban Settings Open

Anastasia Phillips, Max Denning, Em Long-Mills, Dmitry Tumin, Jennifer L. Parker‐Cote , et al. · 2025

Objectives: Barriers to healthcare in rural areas can delay treatment in pediatric patients who have experienced poisoning. We compared emergency medical services (EMS) response times and EMS-reported delays in responding to pediatric pois…

Safety attitudes, burnout and well-being among healthcare workers during the COVID-19 pandemic: an Indo-Pacific regional cross-sectional study Open

Abhiram Kanneganti, Benjamin Yong‐Qiang Tan, Nik Hisamuddin Nik Ab Rahman, Aloysius Sheng‐Ting Leow, Max Denning , et al. · 2022

Introduction: The coronavirus disease 2019 (COVID-19) pandemic has had an unprecedented impact in Asia and has placed significant burden on already stretched healthcare systems. We examined the impact of COVID-19 on the safety attitudes am…

Research evidence. reply to ‘Research requirements for cct across the surgical specialties: why the difference?’ Open

John Whitaker, Max Denning · 2021

Correction to: The PanSurg‐PREDICT Study: Endocrine Surgery During the COVID‐19 Pandemic Open

Klaas Van Den Heede, Swathikan Chidambaram, Jasmine Winter Beatty, Nikita Chander, Sheraz R. Markar , et al. · 2021

A correction to this paper has been published: https://doi.org/10.1007/s00268‐021‐06171‐8

190 Determinants of Psychological Well-Being in Healthcare Workers During the Covid-19 Pandemic: A Multinational Cross-Sectional Study Open

Ee Teng Goh, Max Denning, Sanjay Purkayastha, James Kinross · 2021

Introduction The Covid-19 pandemic has placed unprecedented pressures on healthcare systems globally, impacting working conditions, safety attitudes and the psychological well-being of healthcare workers. This cross-sectional study explore…

Assessing trauma care systems in low-income and middle-income countries: a systematic review and evidence synthesis mapping the Three Delays framework to injury health system assessments Open

John Whitaker, Nollaig O’Donohoe, Max Denning, Dan Poenaru, Elena Guadagno , et al. · 2021

Background The large burden of injuries falls disproportionately on low/middle-income countries (LMICs). Health system interventions improve outcomes in high-income countries. Assessing LMIC trauma systems supports their improvement. Evalu…

Grass-roots junior doctor communication network in response to the COVID-19 pandemic: a service evaluation Open

Arun Sivananthan, Matthew Machin, Geiske Zijlstra, Alexander Harris, Shiva T. Radhakrishnan , et al. · 2021

Background COVID-19 was declared a worldwide pandemic on 11 March 2020. Imperial College Healthcare NHS Trust provides 1412 inpatient beds staffed by 1200 junior doctors and faced a large burden of COVID-19 admissions. Local problem A surv…

The PanSurg‐PREDICT Study: Endocrine Surgery During the COVID‐19 Pandemic Open

Klaas Van Den Heede, Swathikan Chidambaram, Jasmine Winter Beatty, Nikita Chander, Sheraz R. Markar , et al. · 2021

Background In the midst of the COVID‐19 pandemic, patients have continued to present with endocrine (surgical) pathology in an environment depleted of resources. This study investigated how the pandemic affected endocrine surgery practice.…

Determinants of burnout and other aspects of psychological well-being in healthcare workers during the Covid-19 pandemic: A multinational cross-sectional study Open

Max Denning, Ee Teng Goh, Benjamin Yong‐Qiang Tan, Abhiram Kanneganti, Melanie Almonte , et al. · 2021

The Covid-19 pandemic has placed unprecedented pressure on healthcare systems and workers around the world. Such pressures may impact on working conditions, psychological wellbeing and perception of safety. In spite of this, no study has a…

Designing a continuous data-driven feedback and learning initiative to improve electronic prescribing: an interdisciplinary quality improvement study Open

Monsey McLeod, Subrina Farah, K Macaulay, Tej Sheth, Mitesh Patel , et al. · 2021

Introduction The WHO Global Patient Safety Challenge aims to reduce severe avoidable medication-related harm by 50% by 2023[1]. Research suggests that providing timely, trusted feedback that incorporates relevant action can improve practic…

Insights from a global snapshot of the change in elective colorectal practice due to the COVID-19 pandemic Open

Sam Mason, Alasdair Scott, Sheraz R. Markar, Jonathan Clarke, Guy Martin , et al. · 2020

The COVID-19 pandemic was associated with severe restrictions in the availability of colorectal cancer services on a global scale, with significant variation in behaviours which cannot be fully accounted for by hospital burden or mortality.

Burnout and Associated Factors Among Health Care Workers in Singapore During the COVID-19 Pandemic Open

Benjamin Yong‐Qiang Tan, Abhiram Kanneganti, Lucas Lim, Melanie Tan, Ying Xian Chua , et al. · 2020

What Has Been the Impact of Covid-19 on Safety Culture? A Case Study from a Large Metropolitan Healthcare Trust Open

Max Denning, Ee Teng Goh, Alasdair Scott, Guy Martin, Sheraz R. Markar , et al. · 2020

Covid-19 has placed an unprecedented demand on healthcare systems worldwide. A positive safety culture is associated with improved patient safety and, in turn, with patient outcomes. To date, no study has evaluated the impact of Covid-19 o…

Determinants of Burnout and Other Aspects of Psychological Well-Being in Healthcare Workers During the COVID-19 Pandemic: A Multinational Cross-Sectional Study Open

Alasdair Scott, Benjamin Yong‐Qiang Tan, Chan Yiong Huak, Ching‐Hui Sia, Chua Ying Xian , et al. · 2020

Background The Covid-19 pandemic has placed unprecedented pressure on healthcare systems and workers around the world. Such pressures may impact on working conditions, psychological wellbeing and perception of safety. In spite of this, no …

What has been the impact of Covid-19 on Safety Culture? A case study from a large metropolitan teaching hospital Open

Max Denning, Ee Teng Goh, Alasdair Scott, Guy Martin, Sheraz R. Markar , et al. · 2020

Introduction Covid-19 has placed an unprecedented demand on healthcare systems worldwide. A positive safety culture is associated with improved patient safety and in turn patient outcomes. To date, no study has evaluated the impact of Covi…

Changing the Paradigm of Surgical Research During a Pandemic Open

Sheraz R. Markar, Guy Martin, Marta Penna, Seema Yalamanchili, Jasmine Winter Beatty , et al. · 2020

The COVID-19 pandemic has led to a paradigm shift in how we manage surgical patients. As such, there is an immediate need to adapt the traditional model of surgical research in order to create pragmatic studies with adaptive designs in ord…

The Modified Crescenteric Anterior Intercostal Perforator Flap Open

Max Denning, Philippa Hayes, Fiona Tsang, Daniel Leff, Paul Thiruchelvam , et al. · 2020

Summary: Lower pole breast cancers are challenging to manage because conventional wide local excision may produce a “bird’s beak” deformity. In an era of oncoplastic surgery, techniques that balance oncological results with cosmetic outcom…

Global guidance for surgical care during the COVID-19 pandemic Open

Aneel Bhangu, Ismaïl Lawani, Joshua S Ng-Kamstra, Yanfeng Wang, Albert Kam Ming Chan , et al. · 2020

Background Surgeons urgently need guidance on how to deliver surgical services safely and effectively during the COVID-19 pandemic. The aim was to identify the key domains that should be considered when developing pandemic preparedness pla…

Assessing trauma care health systems in low- and middle-income countries, a protocol for a systematic literature review and narrative synthesis Open

John Whitaker, Max Denning, Nollaig O’Donohoe, Dan Poenaru, Elena Guadagno , et al. · 2019

Adoption of a single-page best practice algorithm improves outcomes in patients with acute atrial fibrillation: a multi-disciplinary quality improvement project Open

Edd Maclean, Daniella de Block Golding, Samantha Maden, Shreena Patel, Ola Joseph , et al. · 2019

Introduction: In response to a serious incident involving an atrial fibrillation (AF) associated stroke, a quality improvement project was established to examine and improve all aspects of patient care for individuals pres…

68 Why are patients not more involved in their own safety? A questionnaire-based survey in a multi-ethnic north london population Open

Zouina Assassi, Iman Ahmedani, Wai Yoong, Rhama Abdinasir, Michael Kwakye , et al. · 2019

Background An estimated 8 50 000 cases of unintentional medical injuries occur every year, at least half of which are thought to be preventable. Patients receiving palliative care are particularly vulnerable to medical errors and their con…

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