Maurício Castillo
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View article: Oral Microbiome–Derived Proteins in Brain Extracellular Vesicles Circulate and Tie to Specific Dysbiotic and Neuropathological Profiles in Age-Related Dementias
Oral Microbiome–Derived Proteins in Brain Extracellular Vesicles Circulate and Tie to Specific Dysbiotic and Neuropathological Profiles in Age-Related Dementias Open
The involvement of the oral microbiome (OM) in the pathophysiology of Alzheimer's disease (AD) and vascular dementia (VaD) has been recognized epidemiologically, but the molecular mechanisms remain elusive. In this study, we uncovered the …
View article: CONVENTIONAL CULTURE PRACTICES AND ORGANIZATIONAL SOCIAL HARMONIZATION OF TEACHERS IN PUBLIC ELEMENTARY SCHOOLS
CONVENTIONAL CULTURE PRACTICES AND ORGANIZATIONAL SOCIAL HARMONIZATION OF TEACHERS IN PUBLIC ELEMENTARY SCHOOLS Open
This study explored the conventional culture practices and organizational social harmonization of teachers in public elementary schools. Employing a non-experimental quantitative research design with a correlational approach, the study aim…
View article: CLIENT SATISFACTION FOR A NATIONAL GOVERNMENT AGENCY IN RELATION TO R.A. 11032 (EASE OF DOING BUSINESS AND EFFICIENT GOVERNMENT SERVICE DELIVERY ACT OF 2018)
CLIENT SATISFACTION FOR A NATIONAL GOVERNMENT AGENCY IN RELATION TO R.A. 11032 (EASE OF DOING BUSINESS AND EFFICIENT GOVERNMENT SERVICE DELIVERY ACT OF 2018) Open
Within the competent and effective public service framework which focuses on delivering quality services to citizens, this study evaluated client satisfaction for a national government agency, particularly the Professional Regulation Commi…
View article: Application of Remotely Sensed Data in Estimating Aboveground Biomass and Carbon Stocks
Application of Remotely Sensed Data in Estimating Aboveground Biomass and Carbon Stocks Open
Land degradation directly impacts the aboveground carbon pools, influencing carbon emissions, making its assessment crucial for managing a city's biomass and carbon storage. Although traditional field techniques are accurate, they require …
View article: Strategic Planning for the Management of Educational Institutions: Sistematic Review
Strategic Planning for the Management of Educational Institutions: Sistematic Review Open
This study aimed to analyze the trends and approaches of strategic planning in the management of educational institutions based on a systematic review of the literature of the last five years. Through a comprehensive analysis of 10 studies…
View article: Impact of Articulated Management Models on Educational Quality in Peru: A Systematic Review
Impact of Articulated Management Models on Educational Quality in Peru: A Systematic Review Open
This study aimed to analyze the impact of articulated management models on improving educational quality and equity in Peru. Through a systematic review of the literature with a qualitative approach that applied the PRISMA methodology in t…
View article: Artificial Intelligence–Generated Editorials in Radiology: Can Expert Editors Detect Them?
Artificial Intelligence–Generated Editorials in Radiology: Can Expert Editors Detect Them? Open
GPT-4 can write high-quality articles that iThenticate does not flag as plagiarized, which may go undetected by editors, and that detection tools can detect to a limited extent. Editors showed a positive bias toward human-written articles.
View article: Developing skills for sustainable development through community-focused learning
Developing skills for sustainable development through community-focused learning Open
For engineering students to become leaders in sustainable development, they need to develop the ability to apply empathy in partnership with communities and collaborate across disciplinary boundaries. This is difficult to facilitate in the…
View article: Alpha-methyl acetyl-coA racemase deficiency. Magnetic resonance imaging findings of three patients with encephalopathy, epilepsy, and stroke-like episodes
Alpha-methyl acetyl-coA racemase deficiency. Magnetic resonance imaging findings of three patients with encephalopathy, epilepsy, and stroke-like episodes Open
Alpha-methyl acyl-CoA racemase deficiency (AMACRD) is a rare peroxisomal disorder that results in the accumulation of pristanic acid and 16 cases have been reported in the literature. Here, we present three additional patients, two confirm…
View article: Author Response: Association of Sleep, Neuropsychological Performance, and Gray Matter Volume With Glymphatic Function in Community-Dwelling Older Adults
Author Response: Association of Sleep, Neuropsychological Performance, and Gray Matter Volume With Glymphatic Function in Community-Dwelling Older Adults Open
We appreciate the insightful comments on our study.1 Contrast-based imaging allows direct visualization of the glymphatic system and assessment of its function based on the pharmacokinetics of contrast agents. However, quantifications of g…
View article: Cerebral cavernous malformations: Typical and atypical imaging characteristics
Cerebral cavernous malformations: Typical and atypical imaging characteristics Open
Cavernous malformations (CMs) are benign vascular malformations that maybe seen anywhere in the central nervous system. They are dynamic lesions, growing or shrinking over time and only rarely remaining stable. Size varies from a few milli…
View article: History and Evolution of Brain Tumor Imaging: Insights through Radiology
History and Evolution of Brain Tumor Imaging: Insights through Radiology Open
This review recounts the history of brain tumor diagnosis from antiquity to the present and, indirectly, the history of neuroradiology. Imaging of the brain has from the beginning held an enormous interest because of the inherent difficult…
View article: Peritumoral Brain Edema in Metastases May Be Related to Glymphatic Dysfunction
Peritumoral Brain Edema in Metastases May Be Related to Glymphatic Dysfunction Open
Objectives The proliferation of microvessels with increased permeability is thought to be the cause of peritumoral brain edema (PTBE) in metastases. The contribution of the glymphatic system to the formation of PTBE in brain metastases rem…
View article: Prediction of Malignant Transformation of WHO II Astrocytoma Using Mathematical Models Incorporating Apparent Diffusion Coefficient and Contrast Enhancement
Prediction of Malignant Transformation of WHO II Astrocytoma Using Mathematical Models Incorporating Apparent Diffusion Coefficient and Contrast Enhancement Open
Using only increasing contrast enhancement as a marker of malignant transformation (MT) in gliomas has low specificity and may affect interpretation of clinical outcomes. Therefore we developed a mathematical model to predict MT of low-gra…
View article: From Dysembryoplastic Neuroepithelial Tumors to Myxoid Glioneuronal Tumors, a New Entity
From Dysembryoplastic Neuroepithelial Tumors to Myxoid Glioneuronal Tumors, a New Entity Open
Dysembryoplastic neuroepithelial tumors (DNETs) in the septum pellucidum are now considered a distinct type of lesion: myxoid glioneuronal tumors (MGTs). On the basis of DNA-methylation profile differences between these 2 entities, the c-I…
View article: Acute stroke: basic concepts and use of imaging for clinicians
Acute stroke: basic concepts and use of imaging for clinicians Open
In this article we review basic and some advanced concepts of stroke imaging. The benefits and caveats of both CT and MRI are stressed and we attempt to familiarize the reader with current concepts regarding collateral brain circulation, i…
View article: Roadmap Consensus on Carotid Artery Plaque Imaging and Impact on Therapy Strategies and Guidelines: An International, Multispecialty, Expert Review and Position Statement
Roadmap Consensus on Carotid Artery Plaque Imaging and Impact on Therapy Strategies and Guidelines: An International, Multispecialty, Expert Review and Position Statement Open
Current guidelines for primary and secondary prevention of stroke in patients with carotid atherosclerosis are based on the quantification of the degree of stenosis and symptom status. Recent publications have demonstrated that plaque morp…
View article: Allergic fungal sinusitis: CT findings.
Allergic fungal sinusitis: CT findings. Open
PURPOSE : To determine the computed tomographic (CT) findings in patients with allergic fungal sinusitis. MATERIALS AND METHODS: The authors retrospectively reviewed CT scans and surgical and histopathologic reports in 45 patients (27 male…
View article: Imaging of adult leukodystrophies
Imaging of adult leukodystrophies Open
Leukodystrophies are genetically determined white matter disorders. Even though leukodystrophies essentially affect children in early infancy and childhood, these disorders may affect adults. In adults, leukodystrophies may present a disti…
View article: Neurological complications after H1N1 influenza vaccination: magnetic resonance imaging findings
Neurological complications after H1N1 influenza vaccination: magnetic resonance imaging findings Open
Objective: To report 4 different neurological complications of H1N1 virus vaccination. Method: Four patients (9, 16, 37 and 69 years of age) had neurological symptoms (intracranial hypertension, ataxia, left peripheral facial palsy of abru…
View article: SARS-CoV-2 mass vaccination: Urgent questions on vaccine safety that demand answers from international health agencies, regulatory authorities, governments and vaccine developers
SARS-CoV-2 mass vaccination: Urgent questions on vaccine safety that demand answers from international health agencies, regulatory authorities, governments and vaccine developers Open
Since the start of the COVID-19 outbreak, the race for testing new platforms designed to confer immunity against SARS-CoV-2, has been rampant and unprecedented, leading to conditional emergency authorization of various vaccines. Despite pr…
View article: Peritumoral Brain Edema in Meningiomas May Be Related to Glymphatic Dysfunction
Peritumoral Brain Edema in Meningiomas May Be Related to Glymphatic Dysfunction Open
The pathogenesis of peritumoral brain edema (PTBE) in meningiomas remains unclear. The glymphatic system is recently recognized as a pathway for waste clearance and maintaining fluid balance in the brain parenchymal interstitium. We aimed …
View article: Do left-right and back-front mental timelines activate simultaneously?
Do left-right and back-front mental timelines activate simultaneously? Open
We asked whether it is possible to simultaneously activate two timelines in the human mind. We hypothesized that the lateral (left-right) and sagittal (back-front) spatial dimensions can be coactivated and expected the congruent space-time…