Ian Max Møller
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View article: MULoc-target: Targeting peptide classification and detection using a protein language model
MULoc-target: Targeting peptide classification and detection using a protein language model Open
Protein targeting, often guided by targeting peptides, is a critical biological process that directs proteins to their specific cellular destinations, ensuring proper cellular functionality and organization. Accurate classification and det…
View article: Grounding carbon farming, or how to break the market logic and promote the cocreation of farming systems
Grounding carbon farming, or how to break the market logic and promote the cocreation of farming systems Open
Agricultural soils are central to ecosystem functioning, but their widespread degradation jeopardizes the ability of agroecosystems to sustain life and livelihoods for humans and more-than-humans alike. One proposed solution is carbon farm…
View article: Importance of the leaf respiratory quotient
Importance of the leaf respiratory quotient Open
Rates of leaf respiratory CO 2 ‐release ( R CO2 ) are important for terrestrial biosphere models that estimate carbon exchange between plants and the atmosphere. Hitherto, models of R CO2 have primarily been based on considerations of resp…
View article: Structural Basis for Dityrosine-Mediated Inhibition of α-Synuclein Fibrillization
Structural Basis for Dityrosine-Mediated Inhibition of α-Synuclein Fibrillization Open
α-Synuclein (α-Syn) is an intrinsically disordered protein which self-assembles into highly organized β-sheet structures that accumulate in plaques in brains of Parkinson's disease patients. Oxidative stress influences α-Syn structure and …
View article: Plant mitochondria – past, present and future
Plant mitochondria – past, present and future Open
SUMMARY The study of plant mitochondria started in earnest around 1950 with the first isolations of mitochondria from animal and plant tissues. The first 35 years were spent establishing the basic properties of plant mitochondria and plant…
View article: Mutations of the Genomes Uncoupled 4 Gene Cause ROS Accumulation and Repress Expression of Peroxidase Genes in Rice
Mutations of the Genomes Uncoupled 4 Gene Cause ROS Accumulation and Repress Expression of Peroxidase Genes in Rice Open
The Genomes Uncoupled 4 ( GUN4 ) is one of the retrograde signaling genes in Arabidopsis and its orthologs have been identified in oxygenic phototrophic organisms from cyanobacterium to higher plants. GUN4 is involved in tetrapyrrole biosy…
View article: Insights into triterpene synthesis and unsaturated fatty-acid accumulation provided by chromosomal-level genome analysis of Akebia trifoliata subsp. australis
Insights into triterpene synthesis and unsaturated fatty-acid accumulation provided by chromosomal-level genome analysis of Akebia trifoliata subsp. australis Open
Akebia trifoliata subsp. australis is a well-known medicinal and potential woody oil plant in China. The limited genetic information available for A. trifoliata subsp. australis has hindered its exploitation. Here, a high-quality chromosom…
View article: MULocDeep: A deep-learning framework for protein subcellular and suborganellar localization prediction with residue-level interpretation
MULocDeep: A deep-learning framework for protein subcellular and suborganellar localization prediction with residue-level interpretation Open
Prediction of protein localization plays an important role in understanding protein function and mechanisms. In this paper, we propose a general deep learning-based localization prediction framework, MULocDeep, which can predict multiple l…
View article: Proteomic and Bioinformatic Profiling of Transporters in Higher Plant Mitochondria
Proteomic and Bioinformatic Profiling of Transporters in Higher Plant Mitochondria Open
To function as a metabolic hub, plant mitochondria have to exchange a wide variety of metabolic intermediates as well as inorganic ions with the cytosol. As identified by proteomic profiling or as predicted by MU-LOC, a newly developed bio…
View article: MULocDeep: A deep-learning framework for protein subcellular and suborganellar localization prediction with residue-level interpretation
MULocDeep: A deep-learning framework for protein subcellular and suborganellar localization prediction with residue-level interpretation Open
Prediction of protein localization plays an important role in understanding protein function and mechanism. In this paper, we propose a general deep learning-based localization prediction framework, MULocDeep, which can predict multiple lo…
View article: The effect of phytoglobin overexpression on the plant proteome during nonhost response of barley (Hordeum vulgare) to wheat powdery mildew (Blumeria graminis f. sp. tritici)
The effect of phytoglobin overexpression on the plant proteome during nonhost response of barley (Hordeum vulgare) to wheat powdery mildew (Blumeria graminis f. sp. tritici) Open
Nonhost resistance, a resistance of plant species against all nonadapted pathogens, is considered the most durable and efficient immune system in plants. To increase our understanding of the response of barley plants to infection by powder…
View article: The Hypoxic Proteome and Metabolome of Barley (Hordeum vulgare L.) with and without Phytoglobin Priming
The Hypoxic Proteome and Metabolome of Barley (Hordeum vulgare L.) with and without Phytoglobin Priming Open
Overexpression of phytoglobins (formerly plant hemoglobins) increases the survival rate of plant tissues under hypoxia stress by the following two known mechanisms: (1) scavenging of nitric oxide (NO) in the phytoglobin/NO cycle and (2) mi…
View article: Matrix Redox Physiology Governs the Regulation of Plant Mitochondrial Metabolism through Posttranslational Protein Modifications
Matrix Redox Physiology Governs the Regulation of Plant Mitochondrial Metabolism through Posttranslational Protein Modifications Open
Mitochondria function as hubs of plant metabolism. Oxidative phosphorylation produces ATP, but it is also a central high-capacity electron sink required by many metabolic pathways that must be flexibly coordinated and integrated. Here, we …
View article: Redox-mediated kick-start of mitochondrial energy metabolism drives resource-efficient seed germination
Redox-mediated kick-start of mitochondrial energy metabolism drives resource-efficient seed germination Open
Seeds preserve a far developed plant embryo in a quiescent state. Seed metabolism relies on stored resources and is reactivated to drive germination when the external conditions are favorable. Since the switchover from quiescence to reacti…
View article: The Mitogenome of Norway Spruce and a Reappraisal of Mitochondrial Recombination in Plants
The Mitogenome of Norway Spruce and a Reappraisal of Mitochondrial Recombination in Plants Open
Plant mitogenomes can be difficult to assemble because they are structurally dynamic and prone to intergenomic DNA transfers, leading to the unusual situation where an organelle genome is far outnumbered by its nuclear counterparts. As a r…
View article: Expression of starch-binding factor CBM20 in barley plastids controls the number of starch granules and the level of CO2 fixation
Expression of starch-binding factor CBM20 in barley plastids controls the number of starch granules and the level of CO2 fixation Open
Interference in protein–starch interactions in barley by the expression of an exogenous high-affinity starch-binding factor (Carbohydrate-Binding Motif 20, CBM20) reveals a link between starch granule biosynthesis and the level of photosyn…
View article: A Suppressor Mutation Partially Reverts the xantha Trait via Lowered Methylation in the Promoter of Genomes Uncoupled 4 in Rice
A Suppressor Mutation Partially Reverts the xantha Trait via Lowered Methylation in the Promoter of Genomes Uncoupled 4 in Rice Open
The xantha trait of a yellow leaf rice mutant (HYB), controlled epigenetically by elevated CHG methylation of the genomes uncoupled 4 (OsGUN4) promoter, has reduced chlorophyll content, altered tetrapyrrole biosynthesis, and deregulated tr…
View article: Oxygen: friend and foe!
Oxygen: friend and foe! Open
It is generally believed that the Earth's atmosphere did not contain oxygen until around 2500 million years ago (Mya) when oxygen-evolving photosynthetic bacteria arose. At around 800–500 Mya, the oxygen concentration increased sharply to …
View article: Copper ion / H2O2 oxidation of Cu/Zn-Superoxide dismutase: Implications for enzymatic activity and antioxidant action
Copper ion / H2O2 oxidation of Cu/Zn-Superoxide dismutase: Implications for enzymatic activity and antioxidant action Open
Copper ion-catalyzed oxidation of yeast SOD1 (ySOD1) was examined to determine early oxidative modifications, including oxidation of a crucial disulfide bond, and the structural and functional repercussions of these events. The study used …
View article: The mitogenome of Norway spruce and a reappraisal of mitochondrial recombination in plants
The mitogenome of Norway spruce and a reappraisal of mitochondrial recombination in plants Open
Plant mitogenomes can be difficult to assemble because they are structurally dynamic and prone to intergenomic DNA transfers, leading to the unusual situation where an organelle genome is far outnumbered by its nuclear counterparts. As a r…
View article: Redox-mediated Kick-Start of Mitochondrial Energy Metabolism drives Resource-efficient Seed Germination
Redox-mediated Kick-Start of Mitochondrial Energy Metabolism drives Resource-efficient Seed Germination Open
Seeds preserve a far developed plant embryo in a quiescent state. Seed metabolism relies on stored resources and is re-activated to drive germination when the external conditions are favorable. Since the switchover from quiescence to re-ac…
View article: Overexpression of phytoglobin in barley alters both compatible and incompatible interactions with the mildew pathogen <i>Blumeria graminis</i>
Overexpression of phytoglobin in barley alters both compatible and incompatible interactions with the mildew pathogen <i>Blumeria graminis</i> Open
This study showed how barley plants can be shifted in their response to isolates of the mildew pathogen Blumeria graminis with different host adaptation by overexpression of the barley phytoglobin gene HvHb1 . At early infection stages, pl…
View article: DNA repair in plant mitochondria – a complete base excision repair pathway in potato tuber mitochondria
DNA repair in plant mitochondria – a complete base excision repair pathway in potato tuber mitochondria Open
Mitochondria are one of the major sites of reactive oxygen species (ROS) production in the plant cell. ROS can damage DNA, and this damage is in many organisms mainly repaired by the base excision repair (BER) pathway. We know very little …