Max Salomonsson
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View article: The renal vasodilatation from β‐adrenergic activation in vivo in rats is not driven by K<sub>V</sub>7 and BK<sub>Ca</sub> channels
The renal vasodilatation from β‐adrenergic activation in vivo in rats is not driven by K<sub>V</sub>7 and BK<sub>Ca</sub> channels Open
The mechanisms behind renal vasodilatation elicited by stimulation of β‐adrenergic receptors are not clarified. As several classes of K channels are potentially activated, we tested the hypothesis that KV7 and BKCa channels contribute to t…
View article: The Proportion of FceRI+ Blood Monocytes Increases With the Degree of IgE-Mediated Sensitization in Asthma
The Proportion of FceRI+ Blood Monocytes Increases With the Degree of IgE-Mediated Sensitization in Asthma Open
Study participantsThe study included 67 individuals between 15-41 years old in a 3-5 year follow-up of the MIDAS cohort (Minimally Invasive Diagnostic Procedures in Allergy, Asthma, or Food hypersensitivity), MIDASII.Data from MIDASII have…
View article: Diet-induced hypertension in rats is associated with increased renal vasoconstrictor response to angiotensin II after imitated endothelial dysfunction
Diet-induced hypertension in rats is associated with increased renal vasoconstrictor response to angiotensin II after imitated endothelial dysfunction Open
The mechanisms behind development of diet-induced hypertension remain unclear. The kidneys play a paramount role in blood volume and blood pressure regulation. Increases in renal vascular resistance lead to increased mean arterial blood pr…
View article: Interactions between renal vascular resistance and endothelium‐derived hyperpolarization in hypertensive rats in vivo
Interactions between renal vascular resistance and endothelium‐derived hyperpolarization in hypertensive rats in vivo Open
Endothelium derived signaling mechanisms play an important role in regulating vascular tone and endothelial dysfunction is often found in hypertension. Endothelium-derived hyperpolarization (EDH) plays a significant role in smaller renal a…
View article: Role of age, Rho-kinase 2 expression, and G protein-mediated signaling in the myogenic response in mouse small mesenteric arteries
Role of age, Rho-kinase 2 expression, and G protein-mediated signaling in the myogenic response in mouse small mesenteric arteries Open
MT development in SMAs occurs through a Gαq/11 /PLC/Ca2+ -dependent pathway, and is maintained via ROCK2-mediated Ca2+ sensitization. Increased MT at mature adulthood can be explained by increased ROCK2 exp…
View article: Role of renal vascular potassium channels in physiology and pathophysiology
Role of renal vascular potassium channels in physiology and pathophysiology Open
The control of renal vascular tone is important for the regulation of salt and water balance, blood pressure and the protection against damaging elevated glomerular pressure. The K + conductance is a major factor in the regulation of the m…
View article: T-type Ca<sup>2+</sup>channels and autoregulation of local blood flow
T-type Ca<sup>2+</sup>channels and autoregulation of local blood flow Open
L-type voltage gated Ca2+ channels are considered to be the primary source of calcium influx during the myogenic response. However, many vascular beds also express T-type voltage gated Ca2+ channels. Recent studies su…
View article: A simple method to ensure homogeneous drug distribution during intrarenal infusion
A simple method to ensure homogeneous drug distribution during intrarenal infusion Open
Intrarenal drug infusion plays an important role in renal experimental research. Laminar flow of the blood can cause streaming and inhomogeneous intrarenal distribution of infused drugs. We suggest a simple method to achieve a homogeneous …
View article: Identification of Biological and Pharmaceutical Mast Cell‐ and Basophil‐Related Targets
Identification of Biological and Pharmaceutical Mast Cell‐ and Basophil‐Related Targets Open
Mast cells and basophils have been studied mainly regarding their implication in IgE-mediated allergic disease. Yet, it has become clear that apart from the high-affinity IgE receptor (FcεRI), these cells can respond to many different infl…
View article: Influence of K+-channels and gap junctions on endothelium derived hyperpolarization-induced renal vasodilation in rats
Influence of K+-channels and gap junctions on endothelium derived hyperpolarization-induced renal vasodilation in rats Open