Maxime Battistella
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View article: Lupuslike Manifestations in Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia
Lupuslike Manifestations in Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia Open
Importance Immune-mediated inflammatory diseases are rare but increasingly reported among patients with myelodysplastic syndromes (MDS) or chronic myelomonocytic leukemia (CMML). Systemic lupus erythematosus (LE) and cutaneous LE associate…
View article: #1993 Recommendations on management of adult-onset IgA vasculitis proposed by the European IgA vasculitis study group
#1993 Recommendations on management of adult-onset IgA vasculitis proposed by the European IgA vasculitis study group Open
Background and Aims IgA vasculitis (IgAV) is a small-vessel vasculitis with predominant IgA deposits that involves the skin, the joints, the gastrointestinal tract and the kidneys, causing glomerulonephritis pathologically indistinguishabl…
View article: Mycosis Fungoides in Pediatric Patients Revealed by Recalcitrant Psoriasiform Palmoplantar Keratoderma
Mycosis Fungoides in Pediatric Patients Revealed by Recalcitrant Psoriasiform Palmoplantar Keratoderma Open
Mycosis fungoides is a cutaneous T‐cell lymphoma with a classically relatively good prognosis, mostly diagnosed in men over the age of 50. It classically manifests as erythematosquamous plaques, but can take a variety of forms. Here we des…
View article: Cutaneous Vasculitis in Primary Sjögren Disease
Cutaneous Vasculitis in Primary Sjögren Disease Open
Importance Cutaneous vasculitis (CV) is a heterogenous and severe complication of primary Sjögren disease, often indicating systemic involvement and poor prognosis. Understanding its characteristics and outcomes is essential for patient ma…
View article: Methylation analysis as a diagnostic tool for sweat gland tumours classification with emphasis on the distinction between digital papillary adenocarcinoma and mimickers
Methylation analysis as a diagnostic tool for sweat gland tumours classification with emphasis on the distinction between digital papillary adenocarcinoma and mimickers Open
Aims Digital papillary adenocarcinoma (DPA) is a rare sweat gland carcinoma arising on acral sites. The main differential diagnosis included tubular adenoma, hidradenoma, poroid hidradenoma, and mixed tumours, distinction between DPA and t…
View article: ISCL/EORTC-CLTG/USCLC recommendations for the diagnosis, staging and treatment of early-stage paediatric mycosis fungoides: a modified Delphi consensus. Part two: treatment
ISCL/EORTC-CLTG/USCLC recommendations for the diagnosis, staging and treatment of early-stage paediatric mycosis fungoides: a modified Delphi consensus. Part two: treatment Open
Paediatric mycosis fungoides (MF) is characterized by early-stage disease, a strikingly indolent course and high rates of unusual variants. Despite these clinical peculiarities and the special treatment-related safety considerations in chi…
View article: ISCL/EORTC-CLTG/USCLC recommendations for the diagnosis, staging and treatment of early-stage paediatric mycosis fungoides: a modified Delphi consensus. Part one: diagnosis and staging
ISCL/EORTC-CLTG/USCLC recommendations for the diagnosis, staging and treatment of early-stage paediatric mycosis fungoides: a modified Delphi consensus. Part one: diagnosis and staging Open
Mycosis fungoides (MF) is considered rare in children and adolescents. Accumulating experience indicates that compared with adult patients, almost all paediatric patients with MF are diagnosed at an early stage of disease, exhibit higher r…
View article: <i>NR1D1::MAML3</i> Fusion in an Aggressive Mesenchymal Neoplasm
<i>NR1D1::MAML3</i> Fusion in an Aggressive Mesenchymal Neoplasm Open
NR1D1 ‐rearranged tumors are distinct mesenchymal neoplasms with epithelioid morphology and aggressive potential. This report presents an 85‐year‐old male with a slow‐growing sternal mass identified as a pseudo‐cyst, characterized by a den…
View article: Primary cutaneous <scp>NUT</scp> adnexal carcinoma: morphologic, genetic and methylation analysis of seven new cases with comparison to extracutaneous <scp>NUT</scp> carcinoma and <i>NUTM1</i>‐rearranged porocarcinoma
Primary cutaneous <span>NUT</span> adnexal carcinoma: morphologic, genetic and methylation analysis of seven new cases with comparison to extracutaneous <span>NUT</span> carcinoma and <i>NUTM1</i>‐rearranged porocarcinoma Open
NUT carcinoma is a rare malignant neoplasm characterised by recurrent NUTM1 rearrangements, initially reported in the midline. Recently, 10 cases of cutaneous NUT carcinoma with adnexal differentiation harbouring BRD3::NUTM1 , NSD3::NUTM1 …
View article: Extensive skin necrosis secondary to idiopathic thrombotic vasculopathy associated with ulcerative colitis
Extensive skin necrosis secondary to idiopathic thrombotic vasculopathy associated with ulcerative colitis Open
Cutaneous and mucosal manifestations associated with inflammatory bowel disease are frequent. We report three patients with ulcerative colitis who presented with extensive retiform purpura and/or cutaneous necrosis secondary to idiopathic …
View article: The CD39/CD73/Adenosine and NAD/CD38/CD203a/CD73 Axis in Cutaneous T-Cell Lymphomas
The CD39/CD73/Adenosine and NAD/CD38/CD203a/CD73 Axis in Cutaneous T-Cell Lymphomas Open
Cutaneous T-cell lymphoma (CTCL), characterized by malignant T-cell proliferation primarily in the skin, includes subtypes such as mycosis fungoides (MF) and Sézary syndrome (SS). The tumor microenvironment (TME) is central to their pathog…
View article: Very long-term remission with azacitidine in VEXAS syndrome
Very long-term remission with azacitidine in VEXAS syndrome Open
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View article: Recurrent primary cutaneous marginal zone lymphoma: a comparative study of initial tumours, recurrences, and outcomes in 61 patients
Recurrent primary cutaneous marginal zone lymphoma: a comparative study of initial tumours, recurrences, and outcomes in 61 patients Open
Aims Primary cutaneous marginal zone lymphoma (PCMZL) is considered a lymphoproliferative disorder (International Consensus Classification, ICC) or an overt lymphoma (WHO‐HAEM5). Seeking evidence for a reactive process or true lymphoma, we…
View article: Recurrent <scp><i>GRHL</i></scp> fusions in a subset of sebaceoma: microscopic and molecular characterisation of eight cases
Recurrent <span><i>GRHL</i></span> fusions in a subset of sebaceoma: microscopic and molecular characterisation of eight cases Open
Aims Sebaceous neoplasms constitute a group of adnexal tumours, including sebaceous adenoma, sebaceoma and sebaceous carcinoma. Although mismatch repair deficiency may be observed, the nature of the genetic alterations contributing to the …
View article: Exploring the molecular landscape of cutaneous mixed tumors characterized by <scp> <i>TRPS1</i> </scp> :: <scp> <i>PLAG1</i> </scp> gene fusion
Exploring the molecular landscape of cutaneous mixed tumors characterized by <span> <i>TRPS1</i> </span> :: <span> <i>PLAG1</i> </span> gene fusion Open
The histological similarities between pleomorphic adenomas (PAs) and cutaneous mixed tumors (CMTs) found in certain facial regions can create a diagnostic challenge. Molecular findings reveal common genetic profiles, particularly PLAG1 rea…
View article: Indeterminate DC histiocytosis is distinct from LCH and often associated with other hematopoietic neoplasms
Indeterminate DC histiocytosis is distinct from LCH and often associated with other hematopoietic neoplasms Open
Indeterminate dendritic cell histiocytosis (IDCH) is a rare and poorly understood entity characterized by accumulation of CD1a+/S100+ histiocytes (as Langerhans cell histiocytosis [LCH]) but with reduced-absent expression of Langerin/CD207…
View article: Distinctive genomic features of human T-lymphotropic virus type 1-related adult T-cell leukemia-lymphoma in Western populations
Distinctive genomic features of human T-lymphotropic virus type 1-related adult T-cell leukemia-lymphoma in Western populations Open
Adult T-cell leukemia-lymphoma (ATLL) is an aggressive Human T-cell Leukemia Virus Type 1 (HTLV-1)-driven malignancy. Although Western hemisphere (Afro-Caribbean and South American) patients face worse prognoses, our understanding of ATLL …
View article: Radiotherapy and prognostic factors in adnexal carcinomas: A retrospective study of 657 patients from the French <scp>CARADERM</scp> network
Radiotherapy and prognostic factors in adnexal carcinomas: A retrospective study of 657 patients from the French <span>CARADERM</span> network Open
Background Cutaneous adnexal carcinomas are a heterogeneous group of rare neoplasms. Surgical excision is the first‐line treatment in localized stage. The use and effectiveness of radiotherapy have not been thoroughly evaluated in these ne…
View article: Citrullinated Histone H3, a Marker for Neutrophil Extracellular Traps, Is Associated with Poor Prognosis in Cutaneous Squamous Cell Carcinoma Developing in Patients with Recessive Dystrophic Epidermolysis Bullosa
Citrullinated Histone H3, a Marker for Neutrophil Extracellular Traps, Is Associated with Poor Prognosis in Cutaneous Squamous Cell Carcinoma Developing in Patients with Recessive Dystrophic Epidermolysis Bullosa Open
Recessive dystrophic epidermolysis bullosa (RDEB) is a rare severe hereditary skin disease characterized by skin and mucosa fragility, resulting in blister formation. The most severe complication in RDEB patients is the development of cuta…
View article: Porocarcinomas with <i>PAK1/2/3</i> fusions: a series of 12 cases
Porocarcinomas with <i>PAK1/2/3</i> fusions: a series of 12 cases Open
Aims Porocarcinoma is a malignant sweat gland tumour differentiated toward the upper part of the sweat duct and may arise from the transformation of a preexisting benign poroma. In 2019, Sekine et al. demonstrated the presence of YAP1::MAM…
View article: Efficacy of neoadjuvant pembrolizumab in a primary cutaneous stage II non-operated melanoma
Efficacy of neoadjuvant pembrolizumab in a primary cutaneous stage II non-operated melanoma Open
Dear Editor, Adjuvant treatment in stage III melanoma is now a standard of care and has recently moved towards earlier stages [[1]Luke J.J. Rutkowski P. Queirolo P. et al.Pembrolizumab versus placebo as adjuvant therapy in completely resec…