Maxime Branchereau
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View article: Cytotoxic CD8+ T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling
Cytotoxic CD8+ T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling Open
View article: Cytotoxic CD8+ T Cells Promote Granzyme B-Dependent Adverse Post-Ischemic Cardiac Remodeling
Cytotoxic CD8+ T Cells Promote Granzyme B-Dependent Adverse Post-Ischemic Cardiac Remodeling Open
Acute myocardial infarction (MI) is a common condition responsible for heart failure and sudden death. Here, we show that following acute MI in mice, CD8 + T lymphocytes are recruited and activated in the ischemic heart tissue, and release…
View article: A 3‐week nonalcoholic steatohepatitis mouse model shows elafibranor benefits on hepatic inflammation and cell death
A 3‐week nonalcoholic steatohepatitis mouse model shows elafibranor benefits on hepatic inflammation and cell death Open
The long duration of animal models represents a clear limitation to quickly evaluate the efficacy of drugs targeting nonalcoholic steatohepatitis (NASH). We, therefore, developed a rapid mouse model of liver inflammation (i.e., the mouse f…
View article: Ephrin-B1 blocks adult cardiomyocyte proliferation and heart regeneration
Ephrin-B1 blocks adult cardiomyocyte proliferation and heart regeneration Open
Aims Deciphering the innate mechanisms governing the blockade of proliferation in adult cardiomyocytes (CMs) is challenging for mammalian heart regeneration. Despite the exit of CMs from the cell cycle during the postnatal maturation perio…
View article: Neuronal NO synthase mediates plenylephrine induced cardiomyocyte hypertrophy through facilitation of NFAT-dependent transcriptional activity
Neuronal NO synthase mediates plenylephrine induced cardiomyocyte hypertrophy through facilitation of NFAT-dependent transcriptional activity Open
View article: Macrophage‐derived HMGB1 is dispensable for tissue fibrogenesis
Macrophage‐derived HMGB1 is dispensable for tissue fibrogenesis Open
Alarmins and damage‐associated molecular patterns (DAMPs) are powerful inflammatory mediators, capable of initiating and maintaining sterile inflammation during acute or chronic tissue injury. Recent evidence suggests that alarmins/DAMPs m…
View article: Structural evidence for a new elaborate 3D-organization of the cardiomyocyte lateral membrane in adult mammalian cardiac tissues
Structural evidence for a new elaborate 3D-organization of the cardiomyocyte lateral membrane in adult mammalian cardiac tissues Open
Overall, these results provide the first evidence for the existence of differential CM surface crests in the cardiac tissue as well as the existence of CM-CM direct physical contacts at their lateral face through crest-crest interactions. …
View article: Erratum: Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression
Erratum: Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression Open
View article: Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression
Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression Open
View article: Periodontal dysbiosis linked to periodontitis is associated with cardiometabolic adaptation to high-fat diet in mice
Periodontal dysbiosis linked to periodontitis is associated with cardiometabolic adaptation to high-fat diet in mice Open
Periodontitis and type 2 diabetes are connected pandemic diseases, and both are risk factors for cardiovascular complications. Nevertheless, the molecular factors relating these two chronic pathologies are poorly understood. We have shown …