Maximilian Collatz
YOU?
Author Swipe
View article: AssayBLAST: A Bioinformatic Tool for In Silico Analysis of Molecular Multiparameter Assays
AssayBLAST: A Bioinformatic Tool for In Silico Analysis of Molecular Multiparameter Assays Open
Accurate primer and probe design is essential for molecular applications, including PCR, qPCR, and molecular multiparameter assays like microarrays. The novel software tool AssayBLAST addresses this need by simulating interactions between …
View article: Multiplex Real-Time Polymerase Chain Reaction and Recombinase Polymerase Amplification: Methods for Quick and Cost-Effective Detection of Vancomycin-Resistant Enterococci (VRE)
Multiplex Real-Time Polymerase Chain Reaction and Recombinase Polymerase Amplification: Methods for Quick and Cost-Effective Detection of Vancomycin-Resistant Enterococci (VRE) Open
Background/Objectives: Vancomycin-resistant enterococci (VRE) are one of the leading causes of antibiotic-resistant infections in the hospital setting worldwide, and this has become a major issue, because most patients infected with this s…
View article: Fast and Economic Microarray-Based Detection of Species-, Resistance-, and Virulence-Associated Genes in Clinical Strains of Vancomycin-Resistant Enterococci (VRE)
Fast and Economic Microarray-Based Detection of Species-, Resistance-, and Virulence-Associated Genes in Clinical Strains of Vancomycin-Resistant Enterococci (VRE) Open
Today, there is a continuous worldwide battle against antimicrobial resistance (AMR) and that includes vancomycin-resistant enterococci (VRE). Methods that can adequately and quickly detect transmission chains in outbreaks are needed to tr…
View article: ConsensusPrime—A Bioinformatic Pipeline for Efficient Consensus Primer Design—Detection of Various Resistance and Virulence Factors in MRSA—A Case Study
ConsensusPrime—A Bioinformatic Pipeline for Efficient Consensus Primer Design—Detection of Various Resistance and Virulence Factors in MRSA—A Case Study Open
Background: The effectiveness and reliability of diagnostic tests that detect DNA sequences largely hinge on the quality of the used primers and probes. This importance is especially evident when considering the specific sample being analy…
View article: Molecular Characterization of Chimeric Staphylococcus aureus Strains from Waterfowl
Molecular Characterization of Chimeric Staphylococcus aureus Strains from Waterfowl Open
Staphylococcus aureus is a versatile pathogen that does not only occur in humans but also in various wild and domestic animals, including several avian species. When characterizing S. aureus isolates from waterfowl, isolates were identifie…
View article: ConsensusPrime—A Bioinformatic Pipeline for Ideal Consensus Primer Design
ConsensusPrime—A Bioinformatic Pipeline for Ideal Consensus Primer Design Open
Background: High-quality oligonucleotides for molecular amplification and detection procedures of diverse target sequences depend on sequence homology. Processing input sequences and identifying homogeneous regions in alignments can be car…
View article: ConsensusPrime - a bioinformatic pipeline for alignment filtering and ideal consensus primer design
ConsensusPrime - a bioinformatic pipeline for alignment filtering and ideal consensus primer design Open
High quality oligonucleotides for molecular amplification and detection procedures of diverse target sequences depend on sequence homology. The processing of input sequences and the identification of homogeneous regions in alignments can b…
View article: Description of Staphylococcal Strains from Straw-Coloured Fruit Bat (Eidolon helvum) and Diamond Firetail (Stagonopleura guttata) and a Review of their Phylogenetic Relationships to Other Staphylococci
Description of Staphylococcal Strains from Straw-Coloured Fruit Bat (Eidolon helvum) and Diamond Firetail (Stagonopleura guttata) and a Review of their Phylogenetic Relationships to Other Staphylococci Open
The phylogenetic tree of the Staphylococcus aureus complex consists of several distinct clades and the majority of human and veterinary S. aureus isolates form one large clade. In addition, two divergent clades have recently been described…
View article: Hepatectomy-Induced Alterations in Hepatic Perfusion and Function - Toward Multi-Scale Computational Modeling for a Better Prediction of Post-hepatectomy Liver Function
Hepatectomy-Induced Alterations in Hepatic Perfusion and Function - Toward Multi-Scale Computational Modeling for a Better Prediction of Post-hepatectomy Liver Function Open
Liver resection causes marked perfusion alterations in the liver remnant both on the organ scale (vascular anatomy) and on the microscale (sinusoidal blood flow on tissue level). These changes in perfusion affect hepatic functions via dire…
View article: Characterisation and Molecular Analysis of an Unusual Chimeric Methicillin Resistant Staphylococcus Aureus Strain and its Bacteriophages
Characterisation and Molecular Analysis of an Unusual Chimeric Methicillin Resistant Staphylococcus Aureus Strain and its Bacteriophages Open
In the context of microarray-based epidemiological typing of the clonal organism Staphylococcus aureus /MRSA , a strain was identified that did not belong to known clonal complexes. The molecular analysis by microarray-based typing yielded…
View article: ConsensusPrime - A Bioinformatic Pipeline For Ideal Consensus Primer Design
ConsensusPrime - A Bioinformatic Pipeline For Ideal Consensus Primer Design Open
High quality oligonucleotides for molecular amplification and detection procedures of diverse target sequences depend on sequence homology. The identification of homogeneous regions in alignments can be done manually only if alignments are…
View article: EpiDope: a deep neural network for linear B-cell epitope prediction
EpiDope: a deep neural network for linear B-cell epitope prediction Open
View article: EpiDope: A Deep neural network for linear B-cell epitope prediction
EpiDope: A Deep neural network for linear B-cell epitope prediction Open
By binding to specific structures on antigenic proteins, the so-called epitopes, B-cell antibodies can neutralize pathogens. The identification of B-cell epitopes is of great value for the development of specific serodiagnostic assays and …
View article: Supplement Paper: EpiDope: A Deep neural network for linear B-cellepitope prediction
Supplement Paper: EpiDope: A Deep neural network for linear B-cellepitope prediction Open
View article: A comprehensive annotation and differential expression analysis of short and long non-coding RNAs in 16 bat genomes
A comprehensive annotation and differential expression analysis of short and long non-coding RNAs in 16 bat genomes Open
Although bats are increasingly becoming the focus of scientific studies due to their unique properties, these exceptional animals are still among the least studied mammals. Assembly quality and completeness of bat genomes vary a lot and es…
View article: A comprehensive annotation and differential expression analysis of short and long non-coding RNAs in 16 bat genomes
A comprehensive annotation and differential expression analysis of short and long non-coding RNAs in 16 bat genomes Open
Although bats are increasingly becoming the focus of scientific studies due to their unique properties, these exceptional animals are still among the least studied mammals. Assembly quality and completeness of bat genomes vary a lot and es…
View article: Massive Effect on LncRNAs in Human Monocytes During Fungal and Bacterial Infections and in Response to Vitamins A and D
Massive Effect on LncRNAs in Human Monocytes During Fungal and Bacterial Infections and in Response to Vitamins A and D Open
Mycoses induced by C.albicans or A.fumigatus can cause important host damage either by deficient or exaggerated immune response. Regulation of chemokine and cytokine signaling plays a crucial role for an adequate inflammation, which can be…
View article: Correction: Corrigendum: Differential transcriptional responses to Ebola and Marburg virus infection in bat and human cells
Correction: Corrigendum: Differential transcriptional responses to Ebola and Marburg virus infection in bat and human cells Open
Scientific Reports 6: Article number: 34589; published online: 07 October 2016; updated: 11 January 2017 In this Article, Ivo Grosse is incorrectly affiliated to “Department of Soil Ecology, UFZ - Helmholtz Centre for Environmental Researc…
View article: Differential transcriptional responses to Ebola and Marburg virus infection in bat and human cells
Differential transcriptional responses to Ebola and Marburg virus infection in bat and human cells Open