Maximilian S. Schaefer
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View article: Development and validation of a prediction score for early identification of palliative care needs for patients in the intensive care unit: a multicentre retrospective cohort study
Development and validation of a prediction score for early identification of palliative care needs for patients in the intensive care unit: a multicentre retrospective cohort study Open
View article: Key principles and recent developments for ventilatory management of the surgical critically ill patient
Key principles and recent developments for ventilatory management of the surgical critically ill patient Open
View article: Wireless patches for continuous vital sign monitoring, symptoms and medication at the end-of-life in the palliative care unit: A prospective observational study
Wireless patches for continuous vital sign monitoring, symptoms and medication at the end-of-life in the palliative care unit: A prospective observational study Open
Vital sign monitoring in palliative care could support symptom management and prediction, though its utility at the end-of-life remains critically discussed. This study aims to test a wireless device for continuous vital sign monitoring at…
View article: Dose‐dependent relationship between intra‐operative ketamine administration and postoperative delirium: a retrospective cohort study
Dose‐dependent relationship between intra‐operative ketamine administration and postoperative delirium: a retrospective cohort study Open
Summary Introduction Ketamine is used frequently as an adjunct for general anaesthesia, exerting analgesic and opioid‐sparing properties at lower doses and psychotomimetic effects at higher doses. All dose ranges may have effects on the in…
View article: Temporal stability of inflammatory subphenotypes of acute respiratory distress syndrome: 28-day insights from the ICAR trial
Temporal stability of inflammatory subphenotypes of acute respiratory distress syndrome: 28-day insights from the ICAR trial Open
Inflammatory subphenotypes were stable in COVID-19-related ARDS, with few transitions over 28 days. Monitoring these subphenotypes could be valuable for assessing patient trajectories and treatment responses.
View article: Rapid sequence induction and intubation: Can we predict and prevent hypotension?
Rapid sequence induction and intubation: Can we predict and prevent hypotension? Open
View article: Private equity consolidation in anaesthesiology: trends and sector‐specific investment patterns from 2006 to 2024
Private equity consolidation in anaesthesiology: trends and sector‐specific investment patterns from 2006 to 2024 Open
View article: Development and Validation of a Risk Model to Predict Intraoperative Blood Transfusion
Development and Validation of a Risk Model to Predict Intraoperative Blood Transfusion Open
Importance Crossmatched packed red blood cells (pRBC) that are not transfused result in significant waste of this scarce resource. Efficient utilization should be part of a patient blood management strategy. Objective To develop and valida…
View article: LMFormer: Lane based Motion Prediction Transformer
LMFormer: Lane based Motion Prediction Transformer Open
Motion prediction plays an important role in autonomous driving. This study presents LMFormer, a lane-aware transformer network for trajectory prediction tasks. In contrast to previous studies, our work provides a simple mechanism to dynam…
View article: Association of cannabis use with major cardiovascular and cerebrovascular events after surgery or interventional procedures
Association of cannabis use with major cardiovascular and cerebrovascular events after surgery or interventional procedures Open
Background and Objectives Previous studies reported a predisposition to major adverse cardiovascular or cerebrovascular events (MACCE) in patients consuming cannabis, which might be exacerbated by interventional or surgical procedures. Thi…
View article: Subphenotyping prone position responders with machine learning
Subphenotyping prone position responders with machine learning Open
Background Acute respiratory distress syndrome (ARDS) is a heterogeneous condition with varying response to prone positioning. We aimed to identify subphenotypes of ARDS patients undergoing prone positioning using machine learning and asse…
View article: Analysis of venture capital investments in anaesthesiology companies from 2000 to 2024
Analysis of venture capital investments in anaesthesiology companies from 2000 to 2024 Open
View article: An Infection-Aware Machine Learning Model for Early Mortality Risk Stratification in Sepsis: An International Multi-Cohort Development and Validation Study
An Infection-Aware Machine Learning Model for Early Mortality Risk Stratification in Sepsis: An International Multi-Cohort Development and Validation Study Open
View article: Transpulmonary Pressure as a Predictor of Successful Lung Recruitment: Reanalysis of a Multicenter International Randomized Clinical Trial
Transpulmonary Pressure as a Predictor of Successful Lung Recruitment: Reanalysis of a Multicenter International Randomized Clinical Trial Open
Background: Recruitment maneuvers are used in patients with ARDS to enhance oxygenation and lung mechanics. Heterogeneous lung and chest-wall mechanics lead to unpredictable transpulmonary pressures and could impact recruitment mane…
View article: CASPFormer: Trajectory Prediction from BEV Images with Deformable Attention
CASPFormer: Trajectory Prediction from BEV Images with Deformable Attention Open
Motion prediction is an important aspect for Autonomous Driving (AD) and Advance Driver Assistance Systems (ADAS). Current state-of-the-art motion prediction methods rely on High Definition (HD) maps for capturing the surrounding context o…
View article: Impact of the COVID-19 pandemic on lung-protective ventilation practice in critically ill patients with respiratory failure: a retrospective cohort study from a New England healthcare network
Impact of the COVID-19 pandemic on lung-protective ventilation practice in critically ill patients with respiratory failure: a retrospective cohort study from a New England healthcare network Open
View article: Simplified Mechanical Power Calculation in Patients Receiving Pressure-Regulated, Volume-Targeted Hybrid Modes of Ventilation
Simplified Mechanical Power Calculation in Patients Receiving Pressure-Regulated, Volume-Targeted Hybrid Modes of Ventilation Open
Mechanical power (MP) estimates the energy delivered to the lungs during mechanical ventilation and integrates multiple ventilator parameters including tidal volume (VT), pressure, and breathing frequency.1 Higher levels of MP have been as…
View article: Intraoperative Opioid Waste and Association of Intraoperative Opioid Dose with Postoperative Adverse Outcomes: A Hospital Registry Study
Intraoperative Opioid Waste and Association of Intraoperative Opioid Dose with Postoperative Adverse Outcomes: A Hospital Registry Study Open
View article: Adjustments of Ventilator Parameters during Operating Room–to–ICU Transition and 28-Day Mortality
Adjustments of Ventilator Parameters during Operating Room–to–ICU Transition and 28-Day Mortality Open
Rationale: Lung-protective mechanical ventilation strategies have been proven beneficial in the operating room (OR) and the ICU. However, differential practices in ventilator management persist, often resulting in adjustments of ven…
View article: Affiliation Bias in Peer Review of Abstracts by a Large Language Model
Affiliation Bias in Peer Review of Abstracts by a Large Language Model Open
This study assesses affiliation bias in peer review of medical abstracts by a commonly used large language model.
View article: Palliative care in intensive care
Palliative care in intensive care Open
View article: Inflammatory subphenotypes in patients at risk of ARDS: evidence from the LIPS-A trial
Inflammatory subphenotypes in patients at risk of ARDS: evidence from the LIPS-A trial Open
View article: New onset postoperative depression after major surgery: an analysis from a national claims database
New onset postoperative depression after major surgery: an analysis from a national claims database Open
View article: Assessment of ChatGPT success with specialty medical knowledge using anaesthesiology board examination practice questions
Assessment of ChatGPT success with specialty medical knowledge using anaesthesiology board examination practice questions Open
View article: Discharge Disposition and Loss of Independence Among Survivors of COVID-19 Admitted to Intensive Care: Results From the SCCM Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS)
Discharge Disposition and Loss of Independence Among Survivors of COVID-19 Admitted to Intensive Care: Results From the SCCM Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Open
Objectives To describe incidence and risk factors of loss of previous independent living through nonhome discharge or discharge home with health assistance in survivors of intensive care unit (ICU) admission for coronavirus disease 2019 (C…
View article: Mechanical power and 30-day mortality in mechanically ventilated, critically ill patients with and without Coronavirus Disease-2019: a hospital registry study
Mechanical power and 30-day mortality in mechanically ventilated, critically ill patients with and without Coronavirus Disease-2019: a hospital registry study Open
Background Previous studies linked a high intensity of ventilation, measured as mechanical power, to mortality in patients suffering from “classic” ARDS. By contrast, mechanically ventilated patients with a diagnosis of COVID-19 may presen…
View article: Preoxygenation with standard facemask combining apnoeic oxygenation using high flow nasal cannula versuss standard facemask alone in patients with and without obesity: the OPTIMASK international study
Preoxygenation with standard facemask combining apnoeic oxygenation using high flow nasal cannula versuss standard facemask alone in patients with and without obesity: the OPTIMASK international study Open
Background Combining oxygen facemask with apnoeic oxygenation using high-flow-nasal-oxygen (HFNO) for preoxygenation in the operating room has not been studied against standard oxygen facemask alone. We hypothesized that facemask-alone wou…
View article: Response to: The (Mechanical) Power of (Automated) Ventilation
Response to: The (Mechanical) Power of (Automated) Ventilation Open
Dear Editor, We would like to thank Dr Bruitman-Kruizinga and Dr Schultz for their interest in our study1 and their important comments. The authors postulate that measuring mechanical power from continuous recordings in our study yielded a…
View article: Prevalence and association of non-medical cannabis use with post-procedural healthcare utilisation in patients undergoing surgery or interventional procedures: a retrospective cohort study
Prevalence and association of non-medical cannabis use with post-procedural healthcare utilisation in patients undergoing surgery or interventional procedures: a retrospective cohort study Open
This work was supported by an unrestricted philantropic grant from Jeff and Judy Buzen to Maximilian S. Schaefer.
View article: The association of intraoperative low driving pressure ventilation and nonhome discharge: a historical cohort study
The association of intraoperative low driving pressure ventilation and nonhome discharge: a historical cohort study Open