Maximilian Wege
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View article: Comparative Analysis of Bile-Salt Degradation in <i>Sphingobium</i> sp. Strain Chol11 and Pseudomonas stutzeri Strain Chol1 Reveals Functional Diversity of Proteobacterial Steroid Degradation Enzymes and Suggests a Novel Pathway for Side Chain Degradation
Comparative Analysis of Bile-Salt Degradation in <i>Sphingobium</i> sp. Strain Chol11 and Pseudomonas stutzeri Strain Chol1 Reveals Functional Diversity of Proteobacterial Steroid Degradation Enzymes and Suggests a Novel Pathway for Side Chain Degradation Open
This study highlights the biochemical diversity of bacterial degradation of steroid compounds in different aspects. First, it further elucidates an unexplored variant in the degradation of bile-salt side chains by sphingomonads, a group of…
View article: Comparative analysis of bile-salt degradation in <i>Sphingobium</i> sp. strain Chol11 and <i>P. stutzeri</i> Chol1 reveals functional diversity of β-proteobacterial steroid degradation enzymes and suggests a novel reaction sequence for side-chain degradation involving a hydroxylation step
Comparative analysis of bile-salt degradation in <i>Sphingobium</i> sp. strain Chol11 and <i>P. stutzeri</i> Chol1 reveals functional diversity of β-proteobacterial steroid degradation enzymes and suggests a novel reaction sequence for side-chain degradation involving a hydroxylation step Open
The reaction sequence for aerobic degradation of bile salts by environmental bacteria resembles degradation of other steroid compounds. Recent findings show that bacteria belonging to the Sphingomonadaceae use a pathway variant for bile-sa…