Maxwell L. Smith
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View article: Correction to: Trans-Sigmoidal Endoscopic Ultrasound-Guided Fine-Needle Biopsy of Pancreatic Allograft in Simultaneous Pancreas-Kidney Transplant Recipient: A Novel Approach Following Conventional Technique Failure
Correction to: Trans-Sigmoidal Endoscopic Ultrasound-Guided Fine-Needle Biopsy of Pancreatic Allograft in Simultaneous Pancreas-Kidney Transplant Recipient: A Novel Approach Following Conventional Technique Failure Open
[This corrects the article DOI: 10.14309/crj.0000000000001866.].
View article: Trans-Sigmoidal Endoscopic Ultrasound-Guided Fine-Needle Biopsy of Pancreatic Allograft in Simultaneous Pancreas-Kidney Transplant Recipient: A Novel Approach Following Conventional Technique Failure
Trans-Sigmoidal Endoscopic Ultrasound-Guided Fine-Needle Biopsy of Pancreatic Allograft in Simultaneous Pancreas-Kidney Transplant Recipient: A Novel Approach Following Conventional Technique Failure Open
We report the first known use of a trans-sigmoidal endoscopic ultrasound-guided biopsy in a patient with a simultaneous pancreas-kidney transplant, following failed conventional percutaneous biopsy methods. A 50-year-old man with a simulta…
View article: Chronic Changes on Kidney Histology by a Multiclass Artificial Intelligence Model
Chronic Changes on Kidney Histology by a Multiclass Artificial Intelligence Model Open
A multiclass AI model can help automate quantification of chronic changes on WSIs of kidney histology.
View article: The Clinicopathologic Characteristics of Recurrent Lupus Nephritis Post-Transplant Using Surveillance and Indication Biopsies
The Clinicopathologic Characteristics of Recurrent Lupus Nephritis Post-Transplant Using Surveillance and Indication Biopsies Open
Our study demonstrates that RLN is frequent and may be clinically quiescent. Sequential biopsy evaluation provided an opportunity to study the natural evolution of the disease.
View article: Enhancing Interstitial Lung Disease Diagnoses Through Multimodal <scp>AI</scp> Integration of Histopathological and <scp>CT</scp> Image Data
Enhancing Interstitial Lung Disease Diagnoses Through Multimodal <span>AI</span> Integration of Histopathological and <span>CT</span> Image Data Open
Background and Objective The diagnosis of interstitial lung diseases (ILDs) often relies on the integration of various clinical, radiological, and histopathological data. Achieving high diagnostic accuracy in ILDs, particularly for disting…
View article: Subclinical Pancreas Rejection on Protocol Biopsy Within the First Year of Simultaneous Pancreas Kidney Transplant
Subclinical Pancreas Rejection on Protocol Biopsy Within the First Year of Simultaneous Pancreas Kidney Transplant Open
This single‐center retrospective study investigated subclinical rejection prevalence and significance in simultaneous pancreas and kidney transplant (SPKT) recipients. We analyzed 352 SPKT recipients from July 2003 to April 2022. Our proto…
View article: Pulmonary pathology in vasculitis
Pulmonary pathology in vasculitis Open
Pulmonary involvement is frequent in vasculitis, particularly in ANCA-associated small vessel vasculitis. Laboratory and radiological data alone are often sufficient to confirm the clinical hypothesis, but sometimes the pathologist plays a…
View article: Case report: JC polyomavirus nephropathy in simultaneous heart–kidney transplantation: the role of viral-specific in situ hybridization staining
Case report: JC polyomavirus nephropathy in simultaneous heart–kidney transplantation: the role of viral-specific in situ hybridization staining Open
Introduction JC polyomavirus (JCPyV) is a ubiquitous virus that can be latent in the brain and the kidney. It is the etiologic agent responsible for progressive multifocal leukoencephalopathy, a fatal, demyelinating disease of the central …
View article: Outcomes of asymptomatic histologic pyelonephritis of kidney transplant
Outcomes of asymptomatic histologic pyelonephritis of kidney transplant Open
Background Urinary Tract Infections are the most common post‐transplant infection and can have varied presentations. This study aimed to describe the outcomes of kidney transplant recipients with asymptomatic histologic pyelonephritis on a…
View article: Usefulness and Limitations of Current Diagnostic Strategies for Pulmonary Mucosa–Associated Lymphoid Tissue Lymphoma: Lessons Learned From a Large Cohort
Usefulness and Limitations of Current Diagnostic Strategies for Pulmonary Mucosa–Associated Lymphoid Tissue Lymphoma: Lessons Learned From a Large Cohort Open
Context.— The pathologic diagnosis of pulmonary extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) is challenging. Objective.— To evaluate the diagnostic usefulness and limitations of current diagnostic strategie…
View article: Tubular and Glomerular Size by Cortex Depth as Predictor of Progressive CKD after Radical Nephrectomy for Tumor
Tubular and Glomerular Size by Cortex Depth as Predictor of Progressive CKD after Radical Nephrectomy for Tumor Open
Significance Statement Glomerular size differs by cortex depth. Larger nephrons are prognostic of progressive kidney disease, but it is unknown whether this risk differs by cortex depth or by glomeruli versus proximal or distal tubule size…
View article: Pulmonary Pathology Society Survey on Practice Approaches in the Histologic Diagnosis of Fibrotic Interstitial Lung Disease: Consensus and Opportunities
Pulmonary Pathology Society Survey on Practice Approaches in the Histologic Diagnosis of Fibrotic Interstitial Lung Disease: Consensus and Opportunities Open
Context.— The pathologic diagnosis of usual interstitial pneumonia (UIP) remains a challenging area, and application of histologic UIP guidelines has proved difficult. Objective.— To understand current practice approaches by pulmonary path…
View article: Reflections on the Current Status of Bioethics Education
Reflections on the Current Status of Bioethics Education Open
As bioethics is a field in transition, it is of the utmost importance that we discuss the implications that this flux is having on students and the future generation of bioethicists. While conversations about the regulation of the professi…
View article: Recipient outcomes of donor-derived glomerular fibrin thrombi in deceased donor kidney transplants
Recipient outcomes of donor-derived glomerular fibrin thrombi in deceased donor kidney transplants Open
Background: Deceased donor kidneys with glomerular fibrin thrombi (GFT) are routinely discarded due to perceived poor outcomes.Although good outcomes have been reported, the data is limited.This retrospective case control study has the lar…
View article: Overcoming the Interobserver Variability in Lung Adenocarcinoma Subtyping: A Clustering Approach to Establish a Ground Truth for Downstream Applications
Overcoming the Interobserver Variability in Lung Adenocarcinoma Subtyping: A Clustering Approach to Establish a Ground Truth for Downstream Applications Open
Context.— The accurate identification of different lung adenocarcinoma histologic subtypes is important for determining prognosis but can be challenging because of overlaps in the diagnostic features, leading to considerable interobserver …
View article: Deep learning for histopathological subtyping and grading of lung adenocarcinoma
Deep learning for histopathological subtyping and grading of lung adenocarcinoma Open
The histopathological distinction of lung adenocarcinoma (LADC) subtypes is subject to high inter-observer variability, which can compromise the optimal assessment of the patient prognosis. Therefore, this study developed convolutional neu…
View article: Prognostic Implications of a Morphometric Evaluation for Chronic Changes on All Diagnostic Native Kidney Biopsies
Prognostic Implications of a Morphometric Evaluation for Chronic Changes on All Diagnostic Native Kidney Biopsies Open
Background Semiquantitative visual inspection for glomerulosclerosis, interstitial fibrosis, and arteriosclerosis is often used to assess chronic changes in native kidney biopsies. Morphometric evaluation of these and other chronic changes…
View article: Surgical Pathology of Diffuse Parenchymal Lung Disease in Patients With Psoriasis or Psoriatic Arthritis
Surgical Pathology of Diffuse Parenchymal Lung Disease in Patients With Psoriasis or Psoriatic Arthritis Open
Context.— Diffuse parenchymal lung disease (DPLD) is a well-recognized complication of systemic connective tissue disease (CTD) but rarely arises in patients with psoriasis or psoriatic arthritis, a poorly understood phenomenon. Objective.…
View article: Late Complications of COVID-19
Late Complications of COVID-19 Open
Context.— Studies of lungs in patients with COVID-19 have focused on early findings. Objective.— To systematically study histopathologic and imaging features and presence of SARS-CoV-2 RNA in lung tissue from patients in later stages of CO…
View article: Progressive decline of function in renal allografts with normal 1‐year biopsies: Gene expression studies fail to identify a classifier
Progressive decline of function in renal allografts with normal 1‐year biopsies: Gene expression studies fail to identify a classifier Open
Histologic findings on 1‐year biopsies such as inflammation with fibrosis and transplant glomerulopathy predict renal allograft loss by 5 years. However, almost half of the patients with graft loss have a 1‐year biopsy that is either norma…
View article: Banff consensus recommendations for steatosis assessment in donor livers
Banff consensus recommendations for steatosis assessment in donor livers Open
Background and Aims No consensus criteria or approaches exist regarding assessment of steatosis in the setting of human donor liver suitability for transplantation. The Banff Working Group on Liver Allograft Pathology undertook a study to …
View article: The histologic diagnosis of usual interstitial pneumonia of idiopathic pulmonary fibrosis. Where we are and where we need to go
The histologic diagnosis of usual interstitial pneumonia of idiopathic pulmonary fibrosis. Where we are and where we need to go Open
In the 50 years since its inception by Dr. Liebow, the diagnosis of usual interstitial pneumonia (UIP) by pathologists has changed significantly. This manuscript reviews the progressive history of the histologic diagnosis of UIP and summar…
View article: A Higher Foci Density of Interstitial Fibrosis and Tubular Atrophy Predicts Progressive CKD after a Radical Nephrectomy for Tumor
A Higher Foci Density of Interstitial Fibrosis and Tubular Atrophy Predicts Progressive CKD after a Radical Nephrectomy for Tumor Open
Significance Statement A higher percentage of the kidney cortex area that exhibits interstitial fibrosis/tubular atrophy (IF/TA) is a feature of poor prognosis on biopsy. This study describes IF/TA density (the number of IF/TA foci per are…