May Al‐Sahaf
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View article: A single-cell spatial chart of the airway wall reveals proinflammatory cellular ecosystems and their interactions in health and asthma
A single-cell spatial chart of the airway wall reveals proinflammatory cellular ecosystems and their interactions in health and asthma Open
Determining spatial location of cells within tissues gives vital insight into the interactions between resident and inflammatory cells and is a critical factor for uncoupling the mechanisms driving disease. Here, we apply single-cell spati…
View article: Elective Thoracic Surgical Resections for Pulmonary Arteriovenous Malformations ‐ A 16 Year Single‐Center Experience
Elective Thoracic Surgical Resections for Pulmonary Arteriovenous Malformations ‐ A 16 Year Single‐Center Experience Open
Pulmonary arteriovenous malformations (PAVMs) cause cerebral abscess and ischemic stroke due to paradoxical emboli, risks that are increasingly recognized. We report the evolving placement of thoracic surgery in multi‐disciplinary team man…
View article: KLF6 in Pulmonary Hypertension: The Dual Role of Friend and Foe
KLF6 in Pulmonary Hypertension: The Dual Role of Friend and Foe Open
Background: Pulmonary arterial hypertension (PAH) is a severe lung condition with unmet clinical needs, marked by endothelial damage, excessive repair, and arterial narrowing, though mechanisms remain unclear. Methods: This study investiga…
View article: Mast cell activation disrupts interactions between endothelial cells and pericytes during early life allergic asthma
Mast cell activation disrupts interactions between endothelial cells and pericytes during early life allergic asthma Open
Allergic asthma generally starts during early life and is linked to substantial tissue remodeling and lung dysfunction. Although angiogenesis is a feature of the disrupted airway, the impact of allergic asthma on the pulmonary microcircula…
View article: Mast cell activation disrupts interactions between endothelial cells and pericytes during early life allergic asthma
Mast cell activation disrupts interactions between endothelial cells and pericytes during early life allergic asthma Open
Allergic asthma generally starts during early life and is linked to substantial tissue remodelling and lung dysfunction. Although angiogenesis is a feature of the disrupted airway, the impact of allergic asthma on the pulmonary microcircul…
View article: Maintaining safe lung cancer surgery during the COVID-19 pandemic in a global city
Maintaining safe lung cancer surgery during the COVID-19 pandemic in a global city Open
Background: SARS-CoV-2 has challenged health service provision worldwide. This work evaluates safe surgical pathways and standard operating procedures implemented in the high volume, global city of London during the first wave of SARS-CoV-…
View article: Postoperative chylothorax
Postoperative chylothorax Open
Fortunately, the incidence of postoperative chylothorax is low.Postoperative chylothorax can result from iatrogenic injury to either the thoracic duct or its tributaries during thoracic procedures.Thoracic duct injury has been reported fol…