John H. Wong
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View article: Literature review and DELPHI consensus on follow-up and retreatment of intracranial aneurysms with intrasaccular devices
Literature review and DELPHI consensus on follow-up and retreatment of intracranial aneurysms with intrasaccular devices Open
Background Intracranial aneurysms are increasingly detected incidentally due to broader use of neuroimaging. Intrasaccular devices are frequently used to prevent rupture, yet standardized follow-up and retreatment strategies remain undefin…
View article: Management Approaches to Intraluminal Thrombi in Acutely Symptomatic Carotid Stenosis
Management Approaches to Intraluminal Thrombi in Acutely Symptomatic Carotid Stenosis Open
Background: The presence of an intraluminal thrombus in acutely symptomatic carotid stenosis is thought to represent a high-risk lesion for short-term stroke reccurrence though evidence on natural history and treatment is lacking, leading …
View article: Angiographic Safety and Efficacy of the ReSolv Flow-Diverting Stent in a Rabbit Model
Angiographic Safety and Efficacy of the ReSolv Flow-Diverting Stent in a Rabbit Model Open
Background Bioresorbable polymer-based flow-diverting stents have potential benefits over existing metal devices. This study aimed to evaluate the safety and efficacy of the novel ReSolv device, which is a primarily polymer-based flow-dive…
View article: P.067 The decision to revascularize in symptomatic non-stenotic carotid disease: results from the Hot Carotid Qualitative study
P.067 The decision to revascularize in symptomatic non-stenotic carotid disease: results from the Hot Carotid Qualitative study Open
Background: Little evidence exists to guide the management of symptomatic non-stenotic carotid disease (SyNC). SyNC, which refers to carotid lesions with less than 50% artery stenosis, has been increasingly implicated as a cause of stroke …
View article: P.063 Physician approaches to the initial management of an intraluminal thrombus in recently symptomatic carotid artery stenosis: results from the Hot Carotid Study
P.063 Physician approaches to the initial management of an intraluminal thrombus in recently symptomatic carotid artery stenosis: results from the Hot Carotid Study Open
Background: The presence of intraluminal thrombi (ILT) in acutely symptomatic carotid stenosis (“hot carotid”) represents a therapeutic dilemma for physicians. With little evidence to guide treatment, current ILT management approaches rely…
View article: A Pragmatic Randomized Trial Comparing Surgical Clipping and Endovascular Treatment of Unruptured Intracranial Aneurysms
A Pragmatic Randomized Trial Comparing Surgical Clipping and Endovascular Treatment of Unruptured Intracranial Aneurysms Open
Surgical clipping is more effective than endovascular treatment of unruptured intracranial aneurysms in terms of the frequency of the primary outcome of treatment failure. Results were mainly driven by angiographic results at 1 year.
View article: Physician Approaches to Antithrombotic Therapies for Recently Symptomatic Carotid Stenosis
Physician Approaches to Antithrombotic Therapies for Recently Symptomatic Carotid Stenosis Open
Background: Whereas the beneficial effect of antiplatelet therapy for recurrent stroke prevention has been well established, uncertainties remain regarding the optimal antithrombotic regimen for recently symptomatic carotid stenosis. We so…
View article: Physician Approaches to Imaging and Revascularization for Acutely Symptomatic Carotid Stenosis: Insights from the Hot Carotid Qualitative Study
Physician Approaches to Imaging and Revascularization for Acutely Symptomatic Carotid Stenosis: Insights from the Hot Carotid Qualitative Study Open
Background Evidence informing the choice between carotid endarterectomy and carotid artery stenting for acutely symptomatic carotid stenosis (“hot carotid”) is dated and does not factor in contemporary therapies or techniques. The optimal …
View article: Fluoroscopy, CT, and MR imaging characteristics of a novel primarily bioresorbable flow-diverting stent for aneurysms
Fluoroscopy, CT, and MR imaging characteristics of a novel primarily bioresorbable flow-diverting stent for aneurysms Open
Background Five to ten percent of the global population have unruptured intracranial aneurysms, and ruptured brain aneurysms cause approximately 500,000 deaths a year. Flow-diverting stent treatment is a less invasive intracranial aneurysm…
View article: P.065 Physician Approaches to Anti-thrombotic Therapies for Acutely Symptomatic Carotid Stenosis: Insights from the Hot Carotid Qualitative Study
P.065 Physician Approaches to Anti-thrombotic Therapies for Acutely Symptomatic Carotid Stenosis: Insights from the Hot Carotid Qualitative Study Open
Background: Whereas the beneficial effect of antiplatelet therapy for recurrent stroke prevention is well-established, uncertainties remain regarding the optimal anti-thrombotic regimen for acutely symptomatic carotid stenosis (“hot caroti…
View article: Bilateral Post-Traumatic Carotid-Cavernous Fistulas Presenting with Cerebellar Congestion
Bilateral Post-Traumatic Carotid-Cavernous Fistulas Presenting with Cerebellar Congestion Open
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View article: Findings Predictive of Poor Outcome in Grade 5 Subarachnoid Hemorrhage: A Cohort Study
Findings Predictive of Poor Outcome in Grade 5 Subarachnoid Hemorrhage: A Cohort Study Open
Background: Most patients with World Federation of Neurological Surgeons (WFNS) grade 5 subarachnoid hemorrhage (SAH) have poor outcomes. Accurate assessment of prognosis is important for treatment decisions and conversations with families…
View article: Enhancing Education to Avoid Complications in Endovascular Treatment of Unruptured Intracranial Aneurysms: A Neurointerventionalist’s Perspective
Enhancing Education to Avoid Complications in Endovascular Treatment of Unruptured Intracranial Aneurysms: A Neurointerventionalist’s Perspective Open
It is of utmost importance to avoid errors and subsequent complications when performing neurointerventional procedures, particularly when treating low-risk conditions such as unruptured intracranial aneurysms. We used endovascular treatmen…
View article: Equipoise in Management of Patients With Acute Symptomatic Carotid Stenosis (Hot Carotid)
Equipoise in Management of Patients With Acute Symptomatic Carotid Stenosis (Hot Carotid) Open
Our results highlight the heterogeneous management and community equipoise surrounding optimal antithrombotic regimens for hot carotids.
View article: Practice Current: How do you manage patients with a “hot carotid”?
Practice Current: How do you manage patients with a “hot carotid”? Open
Patients presenting with acutely symptomatic carotid stenosis (a "hot carotid") are known to be at a high up-front risk of recurrent strokes. Uncertainties remain regarding the appropriate management of such patients in the acute period, p…
View article: Rapid cardiac ventricular pacing to facilitate embolization of vein of Galen malformations: technical note
Rapid cardiac ventricular pacing to facilitate embolization of vein of Galen malformations: technical note Open
OBJECTIVE Vein of Galen aneurysmal malformations (VGAMs) in infancy have a poor natural history if left untreated. Their high-flow nature can preclude safe and accurate therapeutic vessel occlusion and the risk of inadvertent pulmonary emb…
View article: A refined experimental model of fusiform aneurysms in a rabbit carotid artery
A refined experimental model of fusiform aneurysms in a rabbit carotid artery Open
OBJECTIVE Reliable animal models are an important aspect of translational research, especially for relatively uncommon clinical entities such as fusiform aneurysms. While several animal models exist, very few are tailored to cerebral fusif…
View article: Surgical clipping or endovascular coiling for unruptured intracranial aneurysms: a pragmatic randomised trial
Surgical clipping or endovascular coiling for unruptured intracranial aneurysms: a pragmatic randomised trial Open
Surgical clipping or endovascular coiling of UIAs did not show differences in morbidity at 1 year. Trial continuation and additional randomised evidence will be necessary to establish the supposed superior efficacy of clipping.
View article: Clinical utility of a screening protocol for blunt cerebrovascular injury using computed tomography angiography
Clinical utility of a screening protocol for blunt cerebrovascular injury using computed tomography angiography Open
OBJECTIVE Blunt cerebrovascular injury (BCVI) occurs in approximately 1% of the blunt trauma population and may lead to stroke and death. Early vascular imaging in asymptomatic patients at high risk of having BCVI may lead to earlier diagn…
View article: Intraoperative indocyanine green videoangiography to guide decision making regarding need for vessel bypass: A case report and technical note
Intraoperative indocyanine green videoangiography to guide decision making regarding need for vessel bypass: A case report and technical note Open
Our case represents a possible use of ICG videoangiography during the operative treatment of a difficult aneurysm. Our patient suffered no infarcts postoperatively. In the correct clinical context, this method represents a possible treatme…