Xu Lin
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View article: VIRMA-mediated SHQ1 m6A modification enhances liver regeneration through an HNRNPA2B1-dependent mechanism
VIRMA-mediated SHQ1 m6A modification enhances liver regeneration through an HNRNPA2B1-dependent mechanism Open
N6-Methyladenosine (m6A) modification is a crucial post-transcriptional regulatory mechanism and the most abundant and highly conserved RNA epigenetic modification in eukaryotes. Previous studies have indicated the involvement of m6A modif…
View article: Study on the Annual Runoff Change and Its Relationship with Fractional Vegetation Cover and Climate Change in the Chinese Yellow River Basin
Study on the Annual Runoff Change and Its Relationship with Fractional Vegetation Cover and Climate Change in the Chinese Yellow River Basin Open
In the context of global climate change and ecological restoration projects, significant changes have been observed in the fractional vegetation cover (FVC) in the Yellow River basin. The increased vegetation growth accelerates water consu…
View article: Mesenchymal stem cell-derived extracellular vesicles: a regulator and carrier for targeting bone-related diseases
Mesenchymal stem cell-derived extracellular vesicles: a regulator and carrier for targeting bone-related diseases Open
The escalating threat of bone-related diseases poses a significant challenge to human health. Mesenchymal stem cell (MSC)-derived extracellular vesicles (MSC-EVs), as inherent cell-secreted natural products, have emerged as promising treat…
View article: Bank Digital Transformation and Enterprise Innovation—Evidence from China
Bank Digital Transformation and Enterprise Innovation—Evidence from China Open
With the rapid advancement of digital technology, the banking industry has embarked on a journey of digital transformation. While existing literature primarily examines how these changes impact the banks themselves, our study focuses on a …
View article: Hot Topic Recognition of Health Rumors Based on Anti-Rumor Articles on the WeChat Official Account Platform: Topic Modeling
Hot Topic Recognition of Health Rumors Based on Anti-Rumor Articles on the WeChat Official Account Platform: Topic Modeling Open
Background Social networks have become one of the main channels for obtaining health information. However, they have also become a source of health-related misinformation, which seriously threatens the public’s physical and mental health. …
View article: The Effects of Online Learning Readiness on Self-Regulated Learning for the First-Time Online Learning Students
The Effects of Online Learning Readiness on Self-Regulated Learning for the First-Time Online Learning Students Open
This study investigated the influence of students' different Online Learning Readiness (OLR) profiles on their Online Self-Regulated Learning (OSRL) strategies in the context of the first online learning experience (FOL) for students. The …
View article: Evaluating the Role of the Communication Skills of Engineering Students on Employability According to the Outcome-Based Education (OBE) Theory
Evaluating the Role of the Communication Skills of Engineering Students on Employability According to the Outcome-Based Education (OBE) Theory Open
With the advent of the digital age and Industry 4.0, the communication skills of engineering students has been exerting gradually increasing influence on the need for enhanced student employability. To address this issue, this study evalua…
View article: Towards the Senior Resident Social Interaction System: A Case Study of Interactive Gallery
Towards the Senior Resident Social Interaction System: A Case Study of Interactive Gallery Open
The number of older adults residing in nursing institutions is increasing, and many of them experience social isolation. The social interaction of older adults constitutes a complex system that involves multiple stakeholders, including fel…
View article: COVID-19 Vaccine–Related Information on the WeChat Public Platform: Topic Modeling and Content Analysis
COVID-19 Vaccine–Related Information on the WeChat Public Platform: Topic Modeling and Content Analysis Open
Background The COVID-19 vaccine is an effective tool in the fight against the COVID-19 outbreak. As the main channel of information dissemination in the context of the epidemic, social media influences public trust and acceptance of the va…
View article: Topic Modeling of Health Rumors Based on Anti-Rumor Tweets on the WeChat Platform: Machine Learning Analysis (Preprint)
Topic Modeling of Health Rumors Based on Anti-Rumor Tweets on the WeChat Platform: Machine Learning Analysis (Preprint) Open
BACKGROUND Social network has become one of the main channels for the public to obtain health information. However, it has also become a source for the spread of health-related misinformation. Health-related misinformation seriously threa…
View article: COVID-19 Vaccine–Related Information on the WeChat Public Platform: Topic Modeling and Content Analysis (Preprint)
COVID-19 Vaccine–Related Information on the WeChat Public Platform: Topic Modeling and Content Analysis (Preprint) Open
BACKGROUND The COVID-19 vaccine is an effective tool in the fight against the COVID-19 outbreak. As the main channel of information dissemination in the context of the epidemic, social media influences public trust and acceptance of the v…
View article: Hot Topic Recognition of Health Rumors Based on Anti-Rumor Articles on the WeChat Official Account Platform: Topic Modeling (Preprint)
Hot Topic Recognition of Health Rumors Based on Anti-Rumor Articles on the WeChat Official Account Platform: Topic Modeling (Preprint) Open
BACKGROUND Social networks have become one of the main channels for obtaining health information. However, they have also become a source of health-related misinformation, which seriously threatens the public’s physical and mental health.…
View article: Assessing the impact of digital education and the role of the big data analytics course to enhance the skills and employability of engineering students
Assessing the impact of digital education and the role of the big data analytics course to enhance the skills and employability of engineering students Open
This study aims to explore the role of digital education in the development of skills and employability for engineering students through researching the role of big data analytics courses. The empirical study proposes the hypothesis that b…
View article: Comparison of single‑nucleus and single‑cell transcriptomes in hepatocellular carcinoma tissue
Comparison of single‑nucleus and single‑cell transcriptomes in hepatocellular carcinoma tissue Open
Single‑nucleus RNA sequencing (snRNA‑seq) is a method used to analyze gene expression in cells for which isolation is complex, such as those in hepatocellular carcinoma (HCC) tissues. It constitutes an alternative to single‑cell RNA sequen…
View article: The Relationship Between Suboptimal Social Networks and Postoperative Delirium: The PNDABLE Study
The Relationship Between Suboptimal Social Networks and Postoperative Delirium: The PNDABLE Study Open
Background Although it has been proven that social networks are related to cognition, studies are conducted to characterize the correlation between social networks and postoperative delirium (POD). Objective We investigated whether subopti…
View article: Testing the Effects of the Digital Linguistic Landscape on Engineering Education for Smart Construction
Testing the Effects of the Digital Linguistic Landscape on Engineering Education for Smart Construction Open
This study investigates the mechanism of digital linguistic landscapes in enabling engineering education for smart construction according to the educational dimensions of A (ability), S (skill), and K (knowledge). A questionnaire survey wa…
View article: The effect of neostigmine on postoperative delirium after colon carcinoma surgery: a randomized, double-blind, controlled trial
The effect of neostigmine on postoperative delirium after colon carcinoma surgery: a randomized, double-blind, controlled trial Open
Background: Postoperative delirium (POD) is a critical complication in patients accepting colon carcinoma surgery. Neostigmine, as a cholinesterase inhibitor, can enhance the transmission of cholinergic transmitters in synaptic space, and …
View article: Application of Machine Learning for the Prediction of Etiological Types of Classic Fever of Unknown Origin
Application of Machine Learning for the Prediction of Etiological Types of Classic Fever of Unknown Origin Open
Background: The etiology of fever of unknown origin (FUO) is complex and remains a major challenge for clinicians. This study aims to investigate the distribution of the etiology of classic FUO and the differences in clinical indicators in…
View article: Multipurpose Mobile Apps for Mental Health in Chinese App Stores: Content Analysis and Quality Evaluation
Multipurpose Mobile Apps for Mental Health in Chinese App Stores: Content Analysis and Quality Evaluation Open
Background Mental disorders impose varying degrees of burden on patients and their surroundings. However, people are reluctant to take the initiative to seek mental health services because of the uneven distribution of resources and stigma…
View article: Multipurpose Mobile Apps for Mental Health in Chinese App Stores: Content Analysis and Quality Evaluation (Preprint)
Multipurpose Mobile Apps for Mental Health in Chinese App Stores: Content Analysis and Quality Evaluation (Preprint) Open
BACKGROUND Mental disorders impose varying degrees of burden on patients and their surroundings. However, people are reluctant to take the initiative to seek mental health services because of the uneven distribution of resources and stigm…
View article: Generalized optical design and optimization of multipass cells with independent circle patterns based on the Monte Carlo and Nelder-Mead simplex algorithms
Generalized optical design and optimization of multipass cells with independent circle patterns based on the Monte Carlo and Nelder-Mead simplex algorithms Open
In this paper, we propose an automatic approach to optimize the multipass cell (MPC) design with independent circle patterns. First, the Monte Carlo algorithm is performed to globally search for the characteristic values of the distance be…