Maya Lichtenstein
YOU?
Author Swipe
View article: Caregiver Strain and Perceived Impact of COVID‐19 on Dementia Caregiving
Caregiver Strain and Perceived Impact of COVID‐19 on Dementia Caregiving Open
Background The COVID‐19 pandemic disproportionately affected people with Alzheimer’s disease and related dementias and their caregivers. Caregivers with high strain may have been particularly vulnerable to disruptions caused by COVID‐19. W…
View article: Group-Based Telehealth Music Therapy Intervention for Patients with Dementia: A Pilot Study
Group-Based Telehealth Music Therapy Intervention for Patients with Dementia: A Pilot Study Open
Background: The behavioral and psychological symptoms in dementia (BPSD) make caregiving particularly challenging. In-person music therapy sessions with a professional have been shown to be helpful for BPSD and reducing caregiver burden. T…
View article: Medical Multimorbidity in Patients with Treatment-Resistant Psychosis and Rare Copy Number Variants: A Retrospective Case Series of 24 Patients
Medical Multimorbidity in Patients with Treatment-Resistant Psychosis and Rare Copy Number Variants: A Retrospective Case Series of 24 Patients Open
Neurodevelopmental disorder-risk CNVs (NDD CNVs) are associated with complex neuropsychiatric phenotypes. These CNVs also confer risk for a host of medical outcomes in adults yet the long-term health consequences in the context of comorbid…
View article: Health System, Community-Based, or Usual Dementia Care for Persons With Dementia and Caregivers
Health System, Community-Based, or Usual Dementia Care for Persons With Dementia and Caregivers Open
Importance The effectiveness of different approaches to dementia care is unknown. Objective To determine the effectiveness of health system–based, community-based dementia care, and usual care for persons with dementia and for caregiver ou…
View article: Obstacles, Opportunities, and Ethical Considerations for Genomic Investigations of Individuals Continuously Hospitalized with Treatment-resistant Schizophrenia
Obstacles, Opportunities, and Ethical Considerations for Genomic Investigations of Individuals Continuously Hospitalized with Treatment-resistant Schizophrenia Open
Background and Hypothesis The overarching objective when studying schizophrenia is the development of generalizable knowledge that improves patient health and/or increases our comprehension of their illness. To fully achieve this objective…
View article: Developmental Delay, Treatment-Resistant Psychosis, and Early-Onset Dementia in a Man With 22q11 Deletion Syndrome and Huntington’s Disease
Developmental Delay, Treatment-Resistant Psychosis, and Early-Onset Dementia in a Man With 22q11 Deletion Syndrome and Huntington’s Disease Open
Schizophrenia usually emerges in late adolescence or early adulthood (1, 2). If cognitive deterioration occurs, it generally appears early and with relatively stable impairment over the next 5–10 years. Later in the illness, psychotic symp…
View article: The dementia care study (D‐CARE): Recruitment strategies and demographic characteristics of participants in a pragmatic randomized trial of dementia care
The dementia care study (D‐CARE): Recruitment strategies and demographic characteristics of participants in a pragmatic randomized trial of dementia care Open
INTRODUCTION Pragmatic research studies that include diverse dyads of persons living with dementia (PLWD) and their family caregivers are rare. METHODS Community‐dwelling dyads were recruited for a pragmatic clinical trial evaluating three…
View article: ENROLLING PARTICIPANTS WITH DEMENTIA IN A RURAL SETTING: GEISINGER RECRUITMENT STRATEGIES FOR D-CARE
ENROLLING PARTICIPANTS WITH DEMENTIA IN A RURAL SETTING: GEISINGER RECRUITMENT STRATEGIES FOR D-CARE Open
Geisinger Health System serves a large, geographically stable population in central and northeast Pennsylvania and was chosen to participate in D-CARE due to its rural population, which is often under-represented. To reach potential partic…
View article: Increased Prevalence of Rare Copy Number Variants in Treatment-Resistant Psychosis
Increased Prevalence of Rare Copy Number Variants in Treatment-Resistant Psychosis Open
Background It remains unknown why ~30% of patients with psychotic disorders fail to respond to treatment. Previous genomic investigations of treatment-resistant psychosis have been inconclusive, but some evidence suggests a possible link b…
View article: Exploring Social Cognition Tests to Differentiate Frontotemporal Dementia from Depression
Exploring Social Cognition Tests to Differentiate Frontotemporal Dementia from Depression Open
Behavioral-variant frontotemporal dementia (bvFTD) is challenging to recognize, and often misdiagnosed as depression (DEP). Evidence suggests changes in social cognition (SoCog) precede general cognitive decline in bvFTD. Currently, there …
View article: Increased Prevalence of Rare Copy Number Variants in Treatment-Resistant Psychosis
Increased Prevalence of Rare Copy Number Variants in Treatment-Resistant Psychosis Open
Background It remains unknown why ∼30% of patients with psychotic disorders fail to respond to treatment. Previous genomic investigations into treatment-resistant psychosis have been inconclusive, but some evidence suggests a possible link…
View article: Population prevalence of autosomal dominant Alzheimer’s disease: A systematic review
Population prevalence of autosomal dominant Alzheimer’s disease: A systematic review Open
Background Alzheimer's disease is the leading cause of dementia, accounting for >50% of cases. Autosomal dominant Alzheimer's Disease (ADAD) is estimated to account for approximately 1% of AD cases. Current estimates of ADAD prevalence hav…
View article: <scp>D‐CARE:</scp> The Dementia Care Study: Design of a Pragmatic Trial of the Effectiveness and Cost Effectiveness of Health System–Based Versus Community‐Based Dementia Care Versus Usual Dementia Care
<span>D‐CARE:</span> The Dementia Care Study: Design of a Pragmatic Trial of the Effectiveness and Cost Effectiveness of Health System–Based Versus Community‐Based Dementia Care Versus Usual Dementia Care Open
BACKGROUND/OBJECTIVES Although several approaches have been developed to provide comprehensive care for persons living with dementia (PWD) and their family or friend caregivers, the relative effectiveness and cost effectiveness of communit…
View article: Psychosis in a Middle-aged Woman
Psychosis in a Middle-aged Woman Open
Uncommon phenotypes of autosomal dominant Alzheimer disease with unusual MRI findings may be challenging for the clinician to recognize, and thus, it is important to be aware of the potential variability of its presentation.
View article: A Method to Estimate Brain Volume from Head CT Images and Application to Detect Brain Atrophy in Alzheimer Disease
A Method to Estimate Brain Volume from Head CT Images and Application to Detect Brain Atrophy in Alzheimer Disease Open
In current clinical practice, brain atrophy is assessed by inaccurate and subjective "eyeballing" of CT images. Manual segmentation of head CT images is prohibitively arduous and time-consuming. CTseg can potentially help clinicians to aut…
View article: P2‐168: IMMUNOHISTOCHEMISTRY OF O‐LINKED N‐ACETYLGLUCOSAMINE TRANSFERASE (OGT) AND AUTOPHAGY MARKER LC3B IN ALZHEIMER'S DISEASE
P2‐168: IMMUNOHISTOCHEMISTRY OF O‐LINKED N‐ACETYLGLUCOSAMINE TRANSFERASE (OGT) AND AUTOPHAGY MARKER LC3B IN ALZHEIMER'S DISEASE Open
Early disturbances in brain glucose metabolism are characteristic in Alzheimer's Disease (AD). Modification of nuclear and cytoplasmic proteins with O-linked N-acetylglucosamine (O-GlcNAc) is dependent on glucose availability. Increased O-…
View article: CJN volume 45 issue 4 Cover and Front matter
CJN volume 45 issue 4 Cover and Front matter Open
An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
View article: 16-Year Survival of the Canadian Collaborative Cohort of Related Dementias
16-Year Survival of the Canadian Collaborative Cohort of Related Dementias Open
Background Survival estimates are integral to care for patients diagnosed with dementia. Few Canadian studies have carried out long-term follow-up of well-described cohorts, analyzing survival related to multiple risk factors. Methods Surv…
View article: Neurobehavioral characterization of adult-onset Alexander disease
Neurobehavioral characterization of adult-onset Alexander disease Open
Alexander disease is a clinically heterogeneous condition associated with glial fibrillary acidic protein (GFAP) gene mutations initially described in infants, but juvenile and adult forms exist. Adult-onset Alexander disease (AOAD) has an…
View article: Higher Plasma LDL-Cholesterol is Associated with Preserved Executive and Fine Motor Functions in Parkinson’s Disease
Higher Plasma LDL-Cholesterol is Associated with Preserved Executive and Fine Motor Functions in Parkinson’s Disease Open
Plasma low density lipoprotein (LDL) cholesterol has been associated both with risk of Parkinson's disease (PD) and with age-related changes in cognitive function. This prospective study examined the relationship between baseline plasma LD…
View article: Statins, plasma cholesterol, and risk of Parkinson's disease: A prospective study
Statins, plasma cholesterol, and risk of Parkinson's disease: A prospective study Open
Previous findings on the association of statins, plasma lipids, and Parkinson's disease (PD) are confounded by the fact that statins also affect lipid profiles. We prospectively examined plasma lipids and statin use in relation to PD in th…