Mayank Goyal
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View article: P129 The hidden link: empyema revealing an underlying rheumatoid arthritis
P129 The hidden link: empyema revealing an underlying rheumatoid arthritis Open
Introduction This case illustrates a uncommon presentation of rheumatoid arthritis which initially mimicked infectious pleural effusion. A 45-year-old male presented in hospital, leading to multiple hospitalisations with recurrent empyema.…
View article: Influence of recent randomized MeVO trials on current practice patterns and future role of MeVO thrombectomy
Influence of recent randomized MeVO trials on current practice patterns and future role of MeVO thrombectomy Open
Introduction Numerous non-randomized studies suggest the benefit of endovascular thrombectomy (EVT) for medium vessel occlusion (MeVO) stroke, while recent randomized trials showed no benefit. In clinical practice, MeVO management remains …
View article: Reperfusion-dependent treatment effects of thrombectomy in patients with large ischemic infarcts
Reperfusion-dependent treatment effects of thrombectomy in patients with large ischemic infarcts Open
Background: While thrombectomy benefits patients with large infarcts, it is unclear whether this benefit persists across different levels of reperfusion. Aims: This study investigates how the degree of reperfusion influences the effectiven…
View article: Mpox: transmission dynamics, treatment, and innovations
Mpox: transmission dynamics, treatment, and innovations Open
The resurgence of monkeypox (mpox), driven by Clade IIb of the monkeypox virus (MPXV), has intensified global concerns about its transmission, treatment, and prevention. Mpox, a zoonotic orthopoxvirus and is primarily transmitted through c…
View article: Association between time and severe hypoperfusion with risk of hemorrhagic transformation in stroke patients
Association between time and severe hypoperfusion with risk of hemorrhagic transformation in stroke patients Open
Introduction: Perfusion imaging studies show a substantially increased risk of hemorrhagic transformation (HT) in severely hypoperfused tissue. Preclinical evidence indicates that ischemic damage is influenced not only by the degree of hyp…
View article: Mission Impossible: Endoscopic Restoration of Gastrointestinal Lumen Continuity
Mission Impossible: Endoscopic Restoration of Gastrointestinal Lumen Continuity Open
Anastomotic leaks following complex gastrointestinal surgeries pose a significant challenge, especially in patients unfit for further surgical intervention. We present a novel 3-staged endoscopic approach to restore gut continuity in a 55-…
View article: The Transformative Impact of Artificial Intelligence on DNA and Fingerprint Analysis in Criminal and Civil Identification: A Comprehensive Review of Technological Advancements, Challenges, and Future Directions
The Transformative Impact of Artificial Intelligence on DNA and Fingerprint Analysis in Criminal and Civil Identification: A Comprehensive Review of Technological Advancements, Challenges, and Future Directions Open
The rapid evolution of artificial intelligence has precipitated a paradigm shift in forensic identification methodologies, particularly in the domains of DNA analysis and fingerprint recognition. This paper presents a systematic examinatio…
View article: Pleural connection treated with stent plus endobronchial valve
Pleural connection treated with stent plus endobronchial valve Open
For nonsurgical candidates with EPF, endoscopic and bronchoscopic management provides a viable alternative. This novel approach of valve deployment within a stent offers a promising, minimally invasive solution for refractory cases.
View article: Association Between Handgrip Strength and Suicidal Ideation: A Systematic Review and Meta‐Analysis
Association Between Handgrip Strength and Suicidal Ideation: A Systematic Review and Meta‐Analysis Open
Background Suicidal ideation is a global public health concern, highlighting the need to identify modifiable risk factors. Handgrip strength (HGS), an objective measure of muscular strength, has been linked to mental health outcomes. This …
View article: Comparing Early National Institutes of Health Stroke Scale Versus 90‐Day Modified Rankin Scale Outcomes in Acute Ischemic Stroke Trials: A Systematic Review and Analysis
Comparing Early National Institutes of Health Stroke Scale Versus 90‐Day Modified Rankin Scale Outcomes in Acute Ischemic Stroke Trials: A Systematic Review and Analysis Open
Background Early National Institutes of Health Stroke Scale (NIHSS) assessment may provide practical benefits over 90‐day modified Rankin Scale (mRS), but it is unclear how it compares in adjudicating randomized clinical trial (RCT) result…
View article: Stepwise improvement in intracerebral haematoma expansion prediction with advanced imaging: a comprehensive comparison of existing scores
Stepwise improvement in intracerebral haematoma expansion prediction with advanced imaging: a comprehensive comparison of existing scores Open
Background We aim to comprehensively assess and compare the predictive performance of haematoma expansion (HE) scores in a homogeneous cohort of acute intracerebral haemorrhage (ICH) patients. Methods Existing scores for predicting HE in a…
View article: Prioritizing gaps in stroke care: A two-round Delphi process
Prioritizing gaps in stroke care: A two-round Delphi process Open
Background: Despite international recognition of stroke as a significant health priority, discrepancies persist between the target values for stroke quality measures and the actual values that are achieved in clinical practice, referred to…
View article: Initial intraventricular involvement and early intracerebral hematoma retraction: The “ventricular washout”
Initial intraventricular involvement and early intracerebral hematoma retraction: The “ventricular washout” Open
Introduction: Intraventricular hematoma (IVH) occurs in approximately 40% of acute intracerebral hemorrhage (ICH) patients and is significantly associated with worse clinical outcomes. According to cerebrospinal fluid dynamics, some blood …
View article: Improvements in endovascular stroke treatment workflow over 5 years: ESCAPE to ESCAPE-NA1
Improvements in endovascular stroke treatment workflow over 5 years: ESCAPE to ESCAPE-NA1 Open
Background and Purpose Rapid treatment is a major determinant of outcome in acute ischemic stroke patients with large vessel occlusion. We used patient-level data from the ESCAPE and ESCAPE-NA1 trials to evaluate whether and to what extent…
View article: Launching Insights: A Pilot Study on Leveraging Real-World Observational Data from the Mayo Clinic Platform to Advance Clinical Research
Launching Insights: A Pilot Study on Leveraging Real-World Observational Data from the Mayo Clinic Platform to Advance Clinical Research Open
Backgrounds: Artificial intelligence (AI) is transforming healthcare, yet translating AI models from theoretical frameworks to real-world clinical applications remains challenging. The Mayo Clinic Platform (MCP) was established to address …
View article: Modified Rankin Scale at 90 Days Versus National Institutes of Health Stroke Scale at 24 Hours as Primary Outcome in Acute Stroke Trials
Modified Rankin Scale at 90 Days Versus National Institutes of Health Stroke Scale at 24 Hours as Primary Outcome in Acute Stroke Trials Open
Background We investigate whether the National Institutes of Health Stroke Scale (NIHSS) at 24 hours could serve as a primary outcome in acute ischemic stroke trials, and whether combining 90‐day modified Rankin Scale (mRS) and 24‐hour NIH…