Mayumi Fujita
YOU?
Author Swipe
View article: An infant with drug reaction with eosinophilia and systemic symptoms caused by phenobarbital and amoxicillin: A case report
An infant with drug reaction with eosinophilia and systemic symptoms caused by phenobarbital and amoxicillin: A case report Open
Rationale: Drug reaction with eosinophilia and systemic symptoms (DRESS) is rare in children, and reports of cases associated with amoxicillin (AMX), the most commonly prescribed antibiotic in children, are extremely rare. Diagnosing DRESS…
View article: Comparative Safety of Baked Egg, Egg Yolk, and Egg White in Young Children with Egg Allergy
Comparative Safety of Baked Egg, Egg Yolk, and Egg White in Young Children with Egg Allergy Open
Introduction: Baked egg (BE) is generally well tolerated by children with egg allergy, and heated egg yolk (EY) is considered less allergenic than egg white (EW). Although these findings suggest that both BE and EY may be safer options for…
View article: Downregulated ALDH2 Contributes to Tumor Progression and Targeted Therapy Resistance in Human Metastatic Melanoma Cells
Downregulated ALDH2 Contributes to Tumor Progression and Targeted Therapy Resistance in Human Metastatic Melanoma Cells Open
Aldehyde dehydrogenase 2 (ALDH2) is a crucial detoxifying enzyme that eliminates toxic aldehydes. ALDH2 deficiency has been linked to various human diseases, including certain cancers. We have previously reported ALDH2 downregulation in hu…
View article: Milk ladder versus early oral immunotherapy in infants with cow's milk protein allergy
Milk ladder versus early oral immunotherapy in infants with cow's milk protein allergy Open
Cow's milk protein allergy (CMPA) significantly decreases the quality of life of infants and their families, necessitating effective management. Avoidance of cow's milk protein (CMP) has been the primary approach, awaiting the development …
View article: Granzyme F: Exhaustion Marker and Modulator of Chimeric Antigen Receptor T Cell–Mediated Cytotoxicity
Granzyme F: Exhaustion Marker and Modulator of Chimeric Antigen Receptor T Cell–Mediated Cytotoxicity Open
Granzymes are a family of proteases used by CD8 T cells to mediate cytotoxicity and other less-defined activities. The substrate and mechanism of action of many granzymes are unknown, although they diverge among the family members. In this…
View article: H3K4me3 remodeling induced acquired resistance through O-GlcNAc transferase
H3K4me3 remodeling induced acquired resistance through O-GlcNAc transferase Open
View article: Allergenicity of partially hydrolyzed whey and casein formulas evaluated by ImmunoCAP inhibition assay and basophil activation test
Allergenicity of partially hydrolyzed whey and casein formulas evaluated by ImmunoCAP inhibition assay and basophil activation test Open
Background When exclusive breastfeeding is not possible, partially hydrolyzed formula (PHF) is often used as a starter formula for infants. Some children develop allergic symptoms, including anaphylaxis, after the first intake of cow prote…
View article: CTLA4 mRNA is downregulated by miR-155 in regulatory T cells, and reduced blood CTLA4 levels are associated with poor prognosis in metastatic melanoma patients
CTLA4 mRNA is downregulated by miR-155 in regulatory T cells, and reduced blood CTLA4 levels are associated with poor prognosis in metastatic melanoma patients Open
Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is an immune checkpoint expressed in regulatory T (Treg) cells and activated T lymphocytes. Despite its potential as a treatment strategy for melanoma, CTLA-4 inhibition has limited effi…
View article: Data from Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma
Data from Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma Open
There is a clear need to identify targetable drivers of resistance and potential biomarkers for salvage therapy for patients with melanoma refractory to the combination of BRAF and MEK inhibition. In this study, we performed whole-exome se…
View article: Supplementary Tables and Figures from Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma
Supplementary Tables and Figures from Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma Open
Supplementary tables and figures
View article: Supplementary File S1 from Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma
Supplementary File S1 from Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma Open
WES MB1998 and MB2132
View article: Supplementary File S1 from Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma
Supplementary File S1 from Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma Open
WES MB1998 and MB2132
View article: Supplementary Tables and Figures from Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma
Supplementary Tables and Figures from Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma Open
Supplementary tables and figures
View article: Data from Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma
Data from Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma Open
There is a clear need to identify targetable drivers of resistance and potential biomarkers for salvage therapy for patients with melanoma refractory to the combination of BRAF and MEK inhibition. In this study, we performed whole-exome se…
View article: Data from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Data from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma Open
Cancers are composed of heterogeneous subpopulations with various tumor-initiating capacities, yet key stem cell genes associated with enhanced tumor-initiating capacities and their regulatory mechanisms remain elusive. Here, we analyzed p…
View article: Supplementary Materials and Methods from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Supplementary Materials and Methods from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma Open
Supplementary Materials and methods. Supplementary figure legends. Supplementary table 1 (PDX tumors) and Supplementary table 3(RT PCR primers)
View article: Supplementary Figure 4 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Supplementary Figure 4 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma Open
Effect of BAY11-7082 on Sox2 subcellular localization. Related to Figure 5
View article: Supplementary Table 2 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Supplementary Table 2 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma Open
Nano String analysis data. Related to Figure 2
View article: Supplementary Figure 2 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Supplementary Figure 2 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma Open
MHC I expression in human melanoma tumors and cell lines. Related to Figure 2
View article: Supplementary Figure 6 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Supplementary Figure 6 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma Open
Kaplan-Meier survival plots for CDK1 expression in melanoma, colon and pancreatic cancer patients. Related to Figure 7
View article: Supplementary Materials and Methods from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Supplementary Materials and Methods from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma Open
Supplementary Materials and methods. Supplementary figure legends. Supplementary table 1 (PDX tumors) and Supplementary table 3(RT PCR primers)
View article: Supplementary Figure 5 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Supplementary Figure 5 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma Open
Luciferase reporter assay using Sox2 response elements. Related to Figure 6
View article: Supplementary Materials and Methods from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Supplementary Materials and Methods from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma Open
Supplementary Materials and methods. Supplementary figure legends. Supplementary table 1 (PDX tumors) and Supplementary table 3(RT PCR primers)
View article: Supplementary Figure 2 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Supplementary Figure 2 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma Open
MHC I expression in human melanoma tumors and cell lines. Related to Figure 2
View article: Supplementary Figure 1 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Supplementary Figure 1 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma Open
Effect of tumor digestion protocol on average viable cell number. Related to Figure 1
View article: Supplementary Figure 3 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Supplementary Figure 3 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma Open
Effect of CDK1 inhibitor on spheroid formation, tumor growth and initiation of melanoma cell lines. Related to Figure 3.
View article: Supplementary Figure 1 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Supplementary Figure 1 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma Open
Effect of tumor digestion protocol on average viable cell number. Related to Figure 1
View article: Supplementary Figure 3 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Supplementary Figure 3 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma Open
Effect of CDK1 inhibitor on spheroid formation, tumor growth and initiation of melanoma cell lines. Related to Figure 3.
View article: Supplementary Figure 5 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Supplementary Figure 5 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma Open
Luciferase reporter assay using Sox2 response elements. Related to Figure 6
View article: Supplementary Figure 4 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Supplementary Figure 4 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma Open
Effect of BAY11-7082 on Sox2 subcellular localization. Related to Figure 5