Carolina Silva
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View article: Lateral flow cell-free transcriptional assay for contaminant detection
Lateral flow cell-free transcriptional assay for contaminant detection Open
Cell free transcriptional biosensors are emerging as a powerful technology, offering enhanced capabilities for detecting chemical contaminants in settings where traditional analytical techniques fall short of societal needs. However, the s…
View article: Atypical plastid genome evolution: Cereus Mill. from distinct environments harbor one of the largest plastid genomes in Cactaceae
Atypical plastid genome evolution: Cereus Mill. from distinct environments harbor one of the largest plastid genomes in Cactaceae Open
Background: Cactaceae has successfully radiated in xeric habitats across the Americas, presenting very distinct morphologies and evolutionary patterns within tribes. This study presents the complete plastomes of C. jamacaru subsp. jamacaru…
View article: Designing a 3D Animation-Based Promotional Video for Sublimation Fabric Product of Asietex
Designing a 3D Animation-Based Promotional Video for Sublimation Fabric Product of Asietex Open
PT. Asietex Sinar Indopratama is a vertically integrated textile manufacturer specializing in the full production cycle—from spinning yarn to producing finished fabrics. The majority (85%) of its top-line fabric output is composed of cotto…
View article: SRCR proteins uncovered: Their crucial role in inflammation
SRCR proteins uncovered: Their crucial role in inflammation Open
The scavenger receptor cysteine-rich (SRCR) superfamily comprises a highly conserved group of extracellular soluble and membrane-attached glycoproteins that function as pattern recognition receptors against a diverse range of pathogenic de…
View article: Hepatitis B Virus Genotypes and Subgenotypes Circulating in Infected Residents in a Country with High Vaccination Rate
Hepatitis B Virus Genotypes and Subgenotypes Circulating in Infected Residents in a Country with High Vaccination Rate Open
Despite the availability of a vaccine against hepatitis B virus (HBV), this infection still causes public health problems, particularly in susceptible populations. In Portugal, universal free vaccination started in 1994, and most HBV infec…
View article: Com@Rehab: An Interactive and Personalised Rehabilitation Activity Based on Virtual Reality
Com@Rehab: An Interactive and Personalised Rehabilitation Activity Based on Virtual Reality Open
Background: This work presents Com@Rehab, a technological patient-centred activity for individuals needing a physical rehabilitation approach and with a specific loss of functionality. Within this scope, this paper focuses on the descripti…
View article: Looking at the Molecular Target of NS5A Inhibitors throughout a Population Highly Affected with Hepatitis C Virus
Looking at the Molecular Target of NS5A Inhibitors throughout a Population Highly Affected with Hepatitis C Virus Open
Hepatitis C virus (HCV) is associated with liver damage and an increased progression rate to cirrhosis and hepatocellular carcinoma. In Portugal, it is prevalent in vulnerable populations such as injection drug users (IDU). HCV is characte…
View article: Supplemental Figures and Tables from An <i>Ex Vivo</i> Platform for the Prediction of Clinical Response in Multiple Myeloma
Supplemental Figures and Tables from An <i>Ex Vivo</i> Platform for the Prediction of Clinical Response in Multiple Myeloma Open
Supplemental Figures and Tables to augment (1) the mathematical modeling (providing details on specific therapeutics); (2) patient characteristics (treatment history, clinical and predicted response), (3) synergistic activities identified …
View article: Recurrent Respiratory Papillomatosis Presenting as Worsening Dyspnea in an HIV-infected Patient
Recurrent Respiratory Papillomatosis Presenting as Worsening Dyspnea in an HIV-infected Patient Open
Recurrent respiratory papillomatosis (RRP) is a rare manifestation of human papillomavirus (HPV) infection. It is characterized by relapsing bulky papillomas in the respiratory tract, which are usually benign in nature. We describe a chall…
View article: LEUCEMIA/LINFOMA DE CÉLULAS T DO ADULTO (ATLL): RELATO DE CASO
LEUCEMIA/LINFOMA DE CÉLULAS T DO ADULTO (ATLL): RELATO DE CASO Open
Relatar um caso de ATLL. Paciente feminina, 43 anos, hipertensa. Há dezoito meses apresentando linfonodos em região occipital e axilar, associada à leucocitose, febre, sudorese noturna e perda ponderal de 15 kg. Exame físico: linfonodomega…
View article: CancerCellTracker: a brightfield time-lapse microscopy framework for cancer drug sensitivity estimation
CancerCellTracker: a brightfield time-lapse microscopy framework for cancer drug sensitivity estimation Open
Motivation Time-lapse microscopy is a powerful technique that relies on images of live cells cultured ex vivo that are captured at regular intervals of time to describe and quantify their behavior under certain experimental conditions. Thi…
View article: Hypovitaminosis D is Associated with the Components of Metabolic Syndrome in Brazilian Women
Hypovitaminosis D is Associated with the Components of Metabolic Syndrome in Brazilian Women Open
Low vitamin D status and oxidative/nitrosative stress have been recognized as risk factor for chronic diseases such as metabolic syndrome (MetS). The objective of this study was to evaluate the metabolic and oxidative/nitrosative markers f…
View article: What goes on in digital behaviour change interventions for weight loss maintenance targeting physical activity: A scoping review
What goes on in digital behaviour change interventions for weight loss maintenance targeting physical activity: A scoping review Open
Objective To identify the core components of digital behaviour change interventions for weight loss maintenance targeting physical activity, in terms of: (i) behaviour change techniques, (ii) mechanisms of action, (iii) modes of delivery, …
View article: A New Look into Cancer—A Review on the Contribution of Vibrational Spectroscopy on Early Diagnosis and Surgery Guidance
A New Look into Cancer—A Review on the Contribution of Vibrational Spectroscopy on Early Diagnosis and Surgery Guidance Open
In 2020, approximately 10 million people died of cancer, rendering this disease the second leading cause of death worldwide. Detecting cancer in its early stages is paramount for patients’ prognosis and survival. Hence, the scientific and …
View article: HEMOGLOBINÚRIA PAROXISTICA NOTURNA E ANEMIA APLÁSTICA – RELATO DE CASO
HEMOGLOBINÚRIA PAROXISTICA NOTURNA E ANEMIA APLÁSTICA – RELATO DE CASO Open
Introdução: A HPN é um distúrbio clonal causado por uma mutação adquirida no gene PIGA das células-tronco hematopoiéticas. O gene PIGA, localizado no cromossomo X, codifica uma proteína que é parte integral da formação da âncora de glicosi…
View article: Evolutionary aspects of the plastomes of subfamily Opuntioideae (Cactaceae)
Evolutionary aspects of the plastomes of subfamily Opuntioideae (Cactaceae) Open
The plastid emerged through endosymbiosis. This organelle has a circular genome (plastome) of 100 to 220 kb with a quadripartite structure and harboring around 130 genes. The plastid genes are mainly involved in two processes, photosynthes…
View article: Metformin Reduces Vascular Assembly in High Glucose-Treated Human Microvascular Endothelial Cells in An AMPK-Independent Manner.
Metformin Reduces Vascular Assembly in High Glucose-Treated Human Microvascular Endothelial Cells in An AMPK-Independent Manner. Open
Our data showed that metformin prevents vessel assembly in HMECs, probably through an AMPKindependent mechanism. Understanding the molecular mechanisms by which this pharmacological agent affects endothelial dysfunction is of paramount imp…
View article: Neuro‐COVID frequency and short‐term outcome in the Northern Portuguese population
Neuro‐COVID frequency and short‐term outcome in the Northern Portuguese population Open
Background and purpose COVID‐19‐related acute neurological phenotypes are being increasingly recognised, with neurological complications reported in more than 30% of hospitalised patients. However, multicentric studies providing a populati…
View article: U.S. Generation Z Consumers' Motivations and Purchase Behavior Towards Secondhand Clothing
U.S. Generation Z Consumers' Motivations and Purchase Behavior Towards Secondhand Clothing Open
The purpose of the study is to identify emerging themes influencing U.S. Gen Z consumers' motivations toward secondhand shopping and their willingness to purchase secondhand clothing. A qualitative method approach was used to conduct 18 in…
View article: IMPACT OF NON-INVASIVE VENTILATION IMMEDIATELY AFTER EXTUBATION ON CLINICAL AND FUNCTIONAL OUTCOMES IN PATIENTS SUBMITTED TO CORONARY ARTERY BYPASS GRAFTING: CLINICAL TRIAL
IMPACT OF NON-INVASIVE VENTILATION IMMEDIATELY AFTER EXTUBATION ON CLINICAL AND FUNCTIONAL OUTCOMES IN PATIENTS SUBMITTED TO CORONARY ARTERY BYPASS GRAFTING: CLINICAL TRIAL Open
Introduction: The application of non-invasive ventilation(NIV) after coronary artery bypass grafting(CABG) brings the possibility of reducing loss of functional capacity and complications in the patient. However, the evidence is controvers…
View article: Readmissions and Mortality During the First Year After Stroke—Data From a Population-Based Incidence Study
Readmissions and Mortality During the First Year After Stroke—Data From a Population-Based Incidence Study Open
Background: After a first-ever-in-a-lifetime stroke (FELS), hospital readmissions are common and associated with increased mortality and morbidity of stroke survivors, thus, raising the overall health burden of stroke. Population-based str…
View article: Perinatal outcomes and vertical transmission by SARS-CoV2 infection (COVID-19) during pregnancy: systematic review and meta-analysis.
Perinatal outcomes and vertical transmission by SARS-CoV2 infection (COVID-19) during pregnancy: systematic review and meta-analysis. Open
Background: COVID-19 is a new pandemic disease with severe respiratory outcome. However, there is little evidence of this condition during pregnancy based on small case series reports. Objective: to perform a systematic review and meta-ana…
View article: Psychosocial stress, depressive signs, resilience and coping strategies in students, professors and employees of the university of campinas (unicamp)
Psychosocial stress, depressive signs, resilience and coping strategies in students, professors and employees of the university of campinas (unicamp) Open
Psychosocial Stress (PS) can trigger physical and mental modifications to the individual, such as cardiovascular changes and the appearance of depressive signs. The improvement of resilience associated to coping strategies are crucial for …
View article: LUPUS PANNICULITIS AS AN INITIAL MANIFESTACION OF SYSTEMIC LUPUS ERYTHEMATOSUS: A CASE REPORT
LUPUS PANNICULITIS AS AN INITIAL MANIFESTACION OF SYSTEMIC LUPUS ERYTHEMATOSUS: A CASE REPORT Open
Systemic Lupus Erythematosus (SLE) is a chronic inflammatory disease with a multifactorial etiology that targets cutaneous involvement. This data contributed to the inclusion of skin lesions as 4 of the 17 new diagnostic criteria of the di…
View article: Magnetic Solid-Phase Microextraction for Lead Detection in Aqueous Samples Using Magnetite Nanoparticles
Magnetic Solid-Phase Microextraction for Lead Detection in Aqueous Samples Using Magnetite Nanoparticles Open
A magnetic solid-phase microextraction procedure was developed to detect lead in aqueous samples by flame atomic absorption spectrometry (FAAS).Fe 3 O 4 nanoparticles were synthesized by coprecipitation and the crystalline phase was confir…