Hyder Osman Mirghani
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View article: Chronotype’s effect on academic achievement and absence from classrooms and clinical sessions among clinical phase medical students at the Faculty of Medicine, University of Tabuk, Saudi Arabia
Chronotype’s effect on academic achievement and absence from classrooms and clinical sessions among clinical phase medical students at the Faculty of Medicine, University of Tabuk, Saudi Arabia Open
Objectives Chronotype refers to an individual’s unique biological clock determined by bedtime preferences and daytime activities. The contradiction between sleep preferences and daily routines (circadian misalignment) could affect academic…
View article: Efficacy of immediate-release versus extended-release metformin on glycemic control and insulin resistance in Saudi patients with type 2 diabetes: A prospective cohort study
Efficacy of immediate-release versus extended-release metformin on glycemic control and insulin resistance in Saudi patients with type 2 diabetes: A prospective cohort study Open
View article: Monitoring free flaps with Cook-Swartz implantable Doppler probe in head-and-neck reconstruction
Monitoring free flaps with Cook-Swartz implantable Doppler probe in head-and-neck reconstruction Open
Postoperative monitoring of free flaps has traditionally been based on clinical assessment, interpretation of which may be subjective. The Cook-Swartz implantable Doppler probe enables continuous objective real-time monitoring of blood flo…
View article: Prevalence and risk factors for post-COVID-19 syndrome on medical students in Tabuk, Saudi Arabia-2023-2024
Prevalence and risk factors for post-COVID-19 syndrome on medical students in Tabuk, Saudi Arabia-2023-2024 Open
A BSTRACT Background: COVID-19 has infected 221 million individuals worldwide and new strains are discovered continuously. An important complication is the post-COVID-19 syndrome that affects various organs with substantial morbidities. St…
View article: The effects of GLP-1 agonists on HbA1c and insulin dose among patients with type 1 diabetes
The effects of GLP-1 agonists on HbA1c and insulin dose among patients with type 1 diabetes Open
Type 1 diabetes mellitus (T1DM) is a common chronic disease, and there is a rising trend globally; insulin is the mainstay therapy. Despite improvements in insulin delivery and monitoring, a significant percentage of patients still fail to…
View article: Imaging findings of irritable bowel syndrome patients, and the diagnostic value of irritable bowel syndrome: A systematic review
Imaging findings of irritable bowel syndrome patients, and the diagnostic value of irritable bowel syndrome: A systematic review Open
BACKGROUND Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal (FGITD) disorder, the diagnosis is based on Rome Criteria and other subjective tools. Because IBS overlaps with other FGITD and organic diseases, and the …
View article: Barriers to glucagon-like peptide-1 agonists used for obesity management among the general population in Tabuk City, Saudi Arabia, and their relation to smoking cessation and antidepressants
Barriers to glucagon-like peptide-1 agonists used for obesity management among the general population in Tabuk City, Saudi Arabia, and their relation to smoking cessation and antidepressants Open
Background Obesity is a chronic inflammatory disease with high morbidity that is decidedly prevalent worldwide and in Saudi Arabia. Glucagon-like peptide 1 receptor agonists (GLP-1 agonists) are broadly used for the management of diabetes …
View article: Eczema and Beyond: The Growing Trend of Complementary and Alternative Medicine
Eczema and Beyond: The Growing Trend of Complementary and Alternative Medicine Open
Background: Eczema, an inflammatory skin disorder, represents the most prevalent dermatological condition in Saudi Arabia. The use of Complementary and Alternative Medicine (CAM) is widespread among individuals with eczema; however, resear…
View article: Metabolic surgery versus usual care effects on mortality among patients with obesity and type 2 diabetes: A systematic review and meta-analysis
Metabolic surgery versus usual care effects on mortality among patients with obesity and type 2 diabetes: A systematic review and meta-analysis Open
Although bariatric surgery is recommended for obesity treatment, there is an increasing trend toward comorbidity-related indications. The effects of bariatric surgery on mortality are inconsistent. This meta-analysis aimed to assess metabo…
View article: Is Anlotinib and Radiotherapy Combination Effective for Non-Small-Cell Lung Cancer with Brain Metastases? A Systematic Scoping Review and Meta-Analysis
Is Anlotinib and Radiotherapy Combination Effective for Non-Small-Cell Lung Cancer with Brain Metastases? A Systematic Scoping Review and Meta-Analysis Open
Background/Objectives: Non-small-cell lung cancer (NSCLC) frequently metastasizes to the brain, significantly impacting patient prognosis and quality of life. Anlotinib, a novel tyrosine kinase inhibitor, has shown promise in treating NSCL…
View article: Validation of the Arabic version of the oral hypoglycemic agent questionnaire version 2 (OHA-Q ver. 2) in Tabuk, Saudi Arabia: A pilot study
Validation of the Arabic version of the oral hypoglycemic agent questionnaire version 2 (OHA-Q ver. 2) in Tabuk, Saudi Arabia: A pilot study Open
Diabetes mellitus is common globally, and the Arab countries are no exception. Oral hypoglycemic agents are major pillars of diabetes management. The Oral Hypoglycemic Agent Questionnaire Version 2 (OHA-Q ver. 2) is unavailable in Arabic. …
View article: Efficacy of Anlotinib Plus Docetaxel in Advanced NSCLC Previously Treated with Platinum-Based Chemotherapy: A Systematic Review and Meta-Analysis
Efficacy of Anlotinib Plus Docetaxel in Advanced NSCLC Previously Treated with Platinum-Based Chemotherapy: A Systematic Review and Meta-Analysis Open
Background/Objectives: Anlotinib is a novel oral antiangiogenic tyrosine kinase inhibitor (TKI) approved as a third-line treatment for advanced non-small-cell lung cancer (NSCLC). However, its efficacy in combination with docetaxel remains…
View article: Microbiome Gut-Brain-Axis: Impact on Brain Development and Mental Health
Microbiome Gut-Brain-Axis: Impact on Brain Development and Mental Health Open
The current discovery that the gut microbiome, which contains roughly 100 trillion microbes, affects health and disease has catalyzed a boom in multidisciplinary research efforts focused on understanding this relationship. Also, it is comm…
View article: METFORMIN THERAPY FOR ACNE VULGARIS AMONG MALES AND FEMALES WITHOUT POLYCYSTIC OVARY SYNDROME: A SYSTEMATIC REVIEW AND META-ANALYSIS
METFORMIN THERAPY FOR ACNE VULGARIS AMONG MALES AND FEMALES WITHOUT POLYCYSTIC OVARY SYNDROME: A SYSTEMATIC REVIEW AND META-ANALYSIS Open
Objectives: There is an association between Acne vulgaris and insulin resistance and metabolic syndrome. Although metformin was effective in polycystic ovary syndrome (PCOS) patients, its effects on acne vulgaris among males and females wi…
View article: Platelets indices clinical implications in diabetes mellitus: A broader insight
Platelets indices clinical implications in diabetes mellitus: A broader insight Open
Platelet indices (PIs) including high mean platelet volume (MPV), plateletcrit (PLC), and platelet distribution width (PLDW) are associated with poor glycemic control. In addition, they can indicate prothrombotic and procoagulation risk am…
View article: Pyoderma Gangrenosum in a Patient With Systemic Lupus Erythematous: a case report and literature review
Pyoderma Gangrenosum in a Patient With Systemic Lupus Erythematous: a case report and literature review Open
Pyoderma gangrenosum (PG) may be primary or associated with various diseases including malignancies, inflammatory bowel diseases, and rheumatic disorders. However, its association with systemic lupus erythematosus (SLE) is extremely rare a…
View article: Dates fruit effects on dyslipidemia among patients with Type-2 diabetes mellitus: A systematic review and meta-analysis of randomized trials
Dates fruit effects on dyslipidemia among patients with Type-2 diabetes mellitus: A systematic review and meta-analysis of randomized trials Open
Objectives: Dyslipidemias are major risk factors for cardiovascular disease, and other comorbidities. The focus on food and nutrition to prevent and treat cardiovascular risk factors including dyslipidemia is a paradigm shift. This is the …
View article: Diabetes distress, the mediator of the poor glycemic control and depression: A meta-analysis
Diabetes distress, the mediator of the poor glycemic control and depression: A meta-analysis Open
BACKGROUND Diabetes-related distress (DRD) is a common psychological disorder specifically associated with diabetes, its cross-talk with depression, and glycated hemoglobin (HbA1c) was discussed controversially. Interventions addressing DR…
View article: Prediabetes and atrial fibrillation risk stratification, phenotyping, and possible reversal to normoglycemia
Prediabetes and atrial fibrillation risk stratification, phenotyping, and possible reversal to normoglycemia Open
Patients admitted with prediabetes and atrial fibrillation are at high risk for major adverse cardiac or cerebrovascular events independent of confounding variables. The shared pathophysiology between these three serious but common disease…
View article: A comparison between transoral endoscopic thyroidectomy vestibular approach and transareolar thyroidectomy regarding postoperative pain and cosmetic outcomes: A systematic review and meta-analysis
A comparison between transoral endoscopic thyroidectomy vestibular approach and transareolar thyroidectomy regarding postoperative pain and cosmetic outcomes: A systematic review and meta-analysis Open
Objectives: Remote scarless surgeries have been developed for cosmetic reasons; literature showed that remote endoscopic surgeries were superior to conventional thyroidectomy. However, no researchers have compared the transoral thyroidecto…
View article: Vitamin D supplementations and mortality among patients with moderate/severe COVID-19: A meta-analysis of randomized controlled trials
Vitamin D supplementations and mortality among patients with moderate/severe COVID-19: A meta-analysis of randomized controlled trials Open
Background: Vitamin D deficiency is associated with severe COVID 19 and poor outcomes. However, the role of Vitamin D supplementation on mortality is controversial. The current meta analysis aimed to investigate the same among patients wit…
View article: Glucagon-like peptide-1 agonists: Role of the gut in hypoglycemia unawareness, and the rationale in type 1 diabetes
Glucagon-like peptide-1 agonists: Role of the gut in hypoglycemia unawareness, and the rationale in type 1 diabetes Open
Type 1 diabetes is increasing and the majority of patients have poor glycemic control. Although advanced technology and nanoparticle use have greatly enhanced insulin delivery and glucose monitoring, weight gain and hypo-glycemia remain ma…
View article: Effectiveness and Outcomes of Endoscopic Sinus Surgery for Nasal Polyps: A Systematic Review
Effectiveness and Outcomes of Endoscopic Sinus Surgery for Nasal Polyps: A Systematic Review Open
Objectives: To investigate the effectiveness and outcomes of endoscopic sinus surgery (ESS) in patients with nasal polyps. Methods: A thorough search was conducted for pertinent literature using PubMed, SCOPUS, Web of Science, Science Dire…
View article: Atorvastatin vs Rosuvastatin in the Prevention of Cardiovascular Events: A Systematic Review
Atorvastatin vs Rosuvastatin in the Prevention of Cardiovascular Events: A Systematic Review Open
The main objective of this study is to compare any differences in the clinical response to rosuvastatin and atorvastatin in patients with cardiovascular disease. PubMed, SCOPUS, Web of Science, Science Direct, and Clinical Key were systema…
View article: The Interaction between Systemic Lupus Erythematosus and Cardiovascular Disease: Systematic Review
The Interaction between Systemic Lupus Erythematosus and Cardiovascular Disease: Systematic Review Open
Patients diagnosed with systemic lupus erythematosus (SLE) face a much greater risk of morbidity and mortality from cardiovascular disease (CVD) when compared to the overall population. Despite numerous case reports and literature reviews …
View article: The Efficacy and Safety of Inclisiran for Low-Density Lipoprotein (LDL) in Patients With Atherosclerotic Cardiovascular Disease (ASCVD): A Systematic Review of Randomized Controlled Trials
The Efficacy and Safety of Inclisiran for Low-Density Lipoprotein (LDL) in Patients With Atherosclerotic Cardiovascular Disease (ASCVD): A Systematic Review of Randomized Controlled Trials Open
View article: Validation of the Arabic Version of the Diabetes Therapy-Related Quality of Life Questionnaire (DTR-QOL) in Tabuk, Saudi Arabia: A Pilot Study
Validation of the Arabic Version of the Diabetes Therapy-Related Quality of Life Questionnaire (DTR-QOL) in Tabuk, Saudi Arabia: A Pilot Study Open
The Arabic version of the DTR-QOL is valid and reliable for use among patients with diabetes in Arab countries and has good sensitivity and consistency.
View article: Knowledge and perception of medical students regarding remote-access thyroidectomy in Tabuk: the effects of extensive counseling—an interventional study
Knowledge and perception of medical students regarding remote-access thyroidectomy in Tabuk: the effects of extensive counseling—an interventional study Open
Introduction Remote-access scarless thyroidectomies are relatively new surgical procedures, and their uptake for cosmetic concerns is rapidly evolving. However, demographic factors, previous thyroid surgery, and culture substantially influ…
View article: Updates on the Association Between Anemia and Heart Failure: A Systematic Review
Updates on the Association Between Anemia and Heart Failure: A Systematic Review Open
View article: Radioactive iodine effects of ovarian reserve: A systematic review and meta-analysis
Radioactive iodine effects of ovarian reserve: A systematic review and meta-analysis Open
Background: Differentiated thyroid carcinoma is common and its rate is on the rise globally, radioactive iodine is widely used as an adjuvant therapy or for remnant ablation. There is growing awareness about the effects of radioactive iodi…