M. Asrafuzzaman Riyadh
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View article: SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity
SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity Open
Numerous viruses use specialized surface molecules called fusogens to enter host cells. Many of these viruses, including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can infect the brain and are associated with severe …
View article: The SARS-CoV-2 spike (S) and the orthoreovirus p15 cause neuronal and glial fusion
The SARS-CoV-2 spike (S) and the orthoreovirus p15 cause neuronal and glial fusion Open
Numerous enveloped viruses use specialized surface molecules called fusogens to enter host cells 1 . During virus replication, these fusogens decorate the host cells membrane enabling them the ability to fuse with neighboring cells, formin…
View article: Disruption of RAB-5 Increases EFF-1 Fusogen Availability at the Cell Surface and Promotes the Regenerative Axonal Fusion Capacity of the Neuron
Disruption of RAB-5 Increases EFF-1 Fusogen Availability at the Cell Surface and Promotes the Regenerative Axonal Fusion Capacity of the Neuron Open
Following a transection injury to the axon, neurons from a number of species have the ability to undergo spontaneous repair via fusion of the two separated axonal fragments. In the nematode Caenorhabditis elegans , this highly efficient re…
View article: Heterozygous mutation to<i>Chd8</i>causes macrocephaly and widespread alteration of neurodevelopmental transcriptional networks in mouse
Heterozygous mutation to<i>Chd8</i>causes macrocephaly and widespread alteration of neurodevelopmental transcriptional networks in mouse Open
Summary The chromatin remodeling gene CHD8 represents a central node in early neurodevelopmental gene networks implicated in autism. We examined the impact of heterozygous germline Chd8 mutation on neurodevelopment in mice. Network analysi…