Meaghan V. Perdue
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View article: Decreased Cerebral Blood Flow in Young Children With Prenatal Alcohol Exposure
Decreased Cerebral Blood Flow in Young Children With Prenatal Alcohol Exposure Open
View article: Sex differences in maturational timing of amygdala and prefrontal cortex volumes and white matter tract microstructure
Sex differences in maturational timing of amygdala and prefrontal cortex volumes and white matter tract microstructure Open
View article: How does SES influence the brain circuitry for literacy? Modeling the association between SES, oral language, white matter integrity, and reading
How does SES influence the brain circuitry for literacy? Modeling the association between SES, oral language, white matter integrity, and reading Open
Reading is pivotal for educational and occupational success, hence, understanding the factors contributing to reading skill variation is a major educational objective. Although cognitive and neurobiological factors that influence reading a…
View article: Associations between white matter asymmetry and communication skills in children with prenatal alcohol exposure
Associations between white matter asymmetry and communication skills in children with prenatal alcohol exposure Open
Our findings show alterations to the white matter asymmetry-language relationship in children with PAE. This may indicate an altered language processing mechanism that could underlie language deficits observed in many individuals with PAE.
View article: Phonological decoding ability is associated with fiber density of the left arcuate fasciculus longitudinally across reading development
Phonological decoding ability is associated with fiber density of the left arcuate fasciculus longitudinally across reading development Open
Numerous studies have linked reading ability to white matter microstructure using diffusion tensor imaging, but findings have been inconsistent and lack specificity. Fiber-specific diffusion-weighted magnetic resonance imaging (dMRI) model…
View article: Altered markers of brain metabolism and excitability are associated with executive functioning in young children exposed to alcohol in utero
Altered markers of brain metabolism and excitability are associated with executive functioning in young children exposed to alcohol in utero Open
View article: The brain’s structural connectivity and pre-reading abilities in young children with prenatal alcohol exposure
The brain’s structural connectivity and pre-reading abilities in young children with prenatal alcohol exposure Open
Children with prenatal alcohol exposure (PAE) may develop a range of neurological and behavioral deficits, including reading and language disorders. Studying the brain's structural connectivity and its relationship to pre-reading/reading s…
View article: Altered markers of brain metabolism and excitability are associated with executive functioning in young children exposed to alcohol<i>in utero</i>
Altered markers of brain metabolism and excitability are associated with executive functioning in young children exposed to alcohol<i>in utero</i> Open
Prenatal alcohol exposure (PAE) is the leading known cause of birth defects and cognitive disabilities, with impacts on brain development and executive functioning. Abnormalities in structural and functional brain features are well-documen…
View article: How Does the Environment Wire the Brain for Literacy? Modeling the Relationship between Ses, White Matter, and Reading
How Does the Environment Wire the Brain for Literacy? Modeling the Relationship between Ses, White Matter, and Reading Open
View article: Structural neural connectivity correlates with pre-reading abilities in preschool children
Structural neural connectivity correlates with pre-reading abilities in preschool children Open
Pre-reading abilities are predictive of later reading ability and can be assessed before reading begins. However, the neural correlates of pre-reading abilities in young children are not fully understood. To address this, we examined 246 d…
View article: Changes in brain metabolite levels across childhood
Changes in brain metabolite levels across childhood Open
Metabolites play important roles in brain development and their levels change rapidly in the prenatal period and during infancy. Metabolite levels are thought to stabilize during childhood, but the development of neurochemistry across earl…
View article: Structural Neural Connectivity Correlates with Pre-Reading Abilities in Preschool Children
Structural Neural Connectivity Correlates with Pre-Reading Abilities in Preschool Children Open
View article: Changes in brain metabolite levels across childhood
Changes in brain metabolite levels across childhood Open
Metabolites play important roles in brain development and their levels change rapidly in the prenatal period and during infancy. Metabolite levels are thought to stabilize during childhood, but the development of neurochemistry across earl…
View article: Reading intervention and neuroplasticity: A systematic review and meta-analysis of brain changes associated with reading intervention
Reading intervention and neuroplasticity: A systematic review and meta-analysis of brain changes associated with reading intervention Open
View article: Widespread effects of <scp>dMRI</scp> data quality on diffusion measures in children
Widespread effects of <span>dMRI</span> data quality on diffusion measures in children Open
Diffusion magnetic resonance imaging (dMRI) datasets are susceptible to several confounding factors related to data quality, which is especially true in studies involving young children. With the recent trend of large‐scale multicenter stu…
View article: Neurite density and arborization is associated with reading skill and phonological processing in children
Neurite density and arborization is associated with reading skill and phonological processing in children Open
In sum, we established that better reading and phonological processing skills are associated with greater tract coherence (lower ODI) and lower neurite density (lower NDI). We interpret these findings as evidence that reading is associated…
View article: Neuroimaging genetic associations between <i>SEMA6D</i>, brain structure, and reading skills
Neuroimaging genetic associations between <i>SEMA6D</i>, brain structure, and reading skills Open
Specific reading disability (SRD) is defined by genetic and neural risk factors that are not fully understood. The current study used imaging genetics methodology to investigate relationships between SEMA6D, brain structure, and rea…
View article: From BDNF to reading: Neural activation and phonological processing as multiple mediators
From BDNF to reading: Neural activation and phonological processing as multiple mediators Open
The BDNF gene is a prominent promoter of neuronal development, maturation and plasticity. Its Val66Met polymorphism affects brain morphology and function within several areas and is associated with several cognitive functions and neurodeve…
View article: From BDNF to reading: Neural activation and phonological processing as multiple mediators
From BDNF to reading: Neural activation and phonological processing as multiple mediators Open
View article: Gray Matter Structure Is Associated with Reading Skill in Typically Developing Young Readers
Gray Matter Structure Is Associated with Reading Skill in Typically Developing Young Readers Open
Research using functional and structural magnetic resonance imaging has identified areas of reduced brain activation and gray matter volume in children and adults with reading disability, but associations between cortical structure and ind…
View article: Putative protective neural mechanisms in prereaders with a family history of dyslexia who subsequently develop typical reading skills
Putative protective neural mechanisms in prereaders with a family history of dyslexia who subsequently develop typical reading skills Open
Developmental dyslexia affects 40–60% of children with a familial risk (FHD+) compared to a general prevalence of 5–10%. Despite the increased risk, about half of FHD+ children develop typical reading abilities (FHD+Typical). Yet the under…
View article: Putative protective neural mechanisms in pre-readers with a family history of dyslexia who subsequently develop typical reading skills
Putative protective neural mechanisms in pre-readers with a family history of dyslexia who subsequently develop typical reading skills Open
Developmental dyslexia is a learning disability characterized by difficulties in word reading. While the prevalence in the general public is around 10-12%, an increased prevalence of 40-60% has been reported for children with a familial ri…
View article: Common variation within the SETBP1 gene is associated with reading-related skills and patterns of functional neural activation
Common variation within the SETBP1 gene is associated with reading-related skills and patterns of functional neural activation Open
View article: Neural correlates of phonological processing: Disrupted in children with dyslexia and enhanced in musically trained children
Neural correlates of phonological processing: Disrupted in children with dyslexia and enhanced in musically trained children Open
View article: Emergence of the neural network underlying phonological processing from the prereading to the emergent reading stage: A longitudinal study
Emergence of the neural network underlying phonological processing from the prereading to the emergent reading stage: A longitudinal study Open
Numerous studies have shown that phonological skills are critical for successful reading acquisition. However, how the brain network supporting phonological processing evolves and how it supports the initial course of learning to read is l…
View article: PVI LDRC Cross Scanner age-brain structure relations
PVI LDRC Cross Scanner age-brain structure relations Open
View article: Examination of cortical structure and reading skills across reading acquisition
Examination of cortical structure and reading skills across reading acquisition Open
An investigation of relationships between early cortical structure (cortical thickness and surface area) and subsequent reading skills during early stages of reading development.
View article: Associations Between Cortical Structure and Reading Skills in Beginning Readers
Associations Between Cortical Structure and Reading Skills in Beginning Readers Open
The acquisition of literacy is a challenging task that engages multiple processing systems to integrate multimodal information. As a result, children exhibit wide variability in reading ability, with the lowest performers classified as hav…