Meera Srinivasan
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View article: Supine hyperinflation and expiratory flow limitation are associated with respiratory arousals and nocturnal hypoventilation in COPD
Supine hyperinflation and expiratory flow limitation are associated with respiratory arousals and nocturnal hypoventilation in COPD Open
Introduction Subjective sleep disturbance is common in chronic obstructive pulmonary disease (COPD) and is related to hyperinflation when supine and tidal expiratory flow limitation (EFL). We hypothesised that abnormalities in supine lung …
View article: Resting Hyperinflation Predicts Incremental Shuttle Walk Distance in Chronic Obstructive Pulmonary Disease
Resting Hyperinflation Predicts Incremental Shuttle Walk Distance in Chronic Obstructive Pulmonary Disease Open
Rationale: The incremental shuttle walk test (ISWT) correlates closely with peak oxygen uptake in COPD and relates to important outcomes such as mortality, response to treatment and hospital readmission. Despite this, there is limit…
View article: The effect of expiratory flow limitation on supine persistent hyperinflation in COPD: a prospective observational study
The effect of expiratory flow limitation on supine persistent hyperinflation in COPD: a prospective observational study Open
Introduction COPD is characterised by airflow obstruction, expiratory airway collapse and closure causing expiratory flow limitation (EFL) and hyperinflation. Supine posture may worsen ventilatory function in COPD, which may cause hyperinf…
View article: Effectiveness of a patient-centred sleep study report in the management of obstructive sleep apnoea
Effectiveness of a patient-centred sleep study report in the management of obstructive sleep apnoea Open
View article: Acute bilateral phrenic nerve neuropathy causing hypercapnic respiratory failure associated with checkpoint inhibitor immunotherapy
Acute bilateral phrenic nerve neuropathy causing hypercapnic respiratory failure associated with checkpoint inhibitor immunotherapy Open
We present two cases of acute hypercapnic respiratory failure due to diaphragmatic dysfunction secondary to bilateral phrenic nerve paralysis, in patients who were receiving immunotherapy for melanoma. Bilateral diaphragmatic paralysis is …
View article: Diabetes Prevalence and Incidence Among Medicare Beneficiaries — United States, 2001–2015
Diabetes Prevalence and Incidence Among Medicare Beneficiaries — United States, 2001–2015 Open
Diabetes affects approximately 12% of the U.S. adult population and approximately 25% of adults aged ≥65 years. From 2009 to 2017, there was no significant change in diabetes prevalence overall or among persons aged 65-79 years (1). Howeve…
View article: Amiodarone in the aged
Amiodarone in the aged Open
Amiodarone is a highly effective antiarrhythmic drug, but can have serious adverse effects, particularly in older patients. If possible it should not be used purely for controlling the heart rate If a prescription for amiodarone is contemp…
View article: Trends in cause-specific mortality among adults with and without diagnosed diabetes in the USA: an epidemiological analysis of linked national survey and vital statistics data
Trends in cause-specific mortality among adults with and without diagnosed diabetes in the USA: an epidemiological analysis of linked national survey and vital statistics data Open
View article: ACUTE, SUB-ACUTE (28-DAYS), AND SUB-CHRONIC (90-DAYS) ORAL TOXICITY STUDIES OF NANDHI MEZHUGU
ACUTE, SUB-ACUTE (28-DAYS), AND SUB-CHRONIC (90-DAYS) ORAL TOXICITY STUDIES OF NANDHI MEZHUGU Open
Nandhi Mezhugu (NM) is a classical Siddha herbo-mineral formulation indicated for all types of Arthritides.Acute toxicity study was performed at 3 dose levels, i.e., 50, 300, and 2000 mg/kg body weight of rats.Sub-acute toxicity study was …
View article: Identification of Respiratory Viral Infection in Hematopoietic Stem Cell Transplant Recipients - Impact on Non Relapse Mortality
Identification of Respiratory Viral Infection in Hematopoietic Stem Cell Transplant Recipients - Impact on Non Relapse Mortality Open