Megan E. Tipps
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View article: Ethanol-induced suppression of GIRK-dependent signaling in the basal amygdala
Ethanol-induced suppression of GIRK-dependent signaling in the basal amygdala Open
View article: Ethanol-Induced Suppression of G Protein–Gated Inwardly Rectifying K+–Dependent Signaling in the Basal Amygdala
Ethanol-Induced Suppression of G Protein–Gated Inwardly Rectifying K+–Dependent Signaling in the Basal Amygdala Open
View article: E-077 Pipeline embolization of MCA aneurysms in the M2-M4 Segment: Multicenter cohort and meta-analysis
E-077 Pipeline embolization of MCA aneurysms in the M2-M4 Segment: Multicenter cohort and meta-analysis Open
Introduction/Purpose Flow diversion of distal MCA aneurysms in the M2-M4 segments with PED is promising, but further study is needed. Here, we seek to quantify the safety and efficacy of Pipeline embolization in the M2-M4 region in a multi…
View article: E-078 Pipeline embolization of proximal middle cerebral artery aneurysms: A multicenter cohort study
E-078 Pipeline embolization of proximal middle cerebral artery aneurysms: A multicenter cohort study Open
Introduction/Purpose Flow diversion of aneurysms located in the M1 segment and middle cerebral artery bifurcation with Pipeline embolization device is sometimes performed, but further study is needed to support its regular use in aneurysm …
View article: Pipeline embolization of proximal middle cerebral artery aneurysms: A multicenter cohort study
Pipeline embolization of proximal middle cerebral artery aneurysms: A multicenter cohort study Open
Background and purpose Flow diversion of aneurysms located in the M1 segment and middle cerebral artery bifurcation with Pipeline embolization device is sometimes performed, but further study is needed to support its regular use in aneurys…
View article: Pipeline embolization of distal posterior inferior cerebellar artery aneurysms
Pipeline embolization of distal posterior inferior cerebellar artery aneurysms Open
Background and purpose Flow diversion is commonly used to treat intracranial aneurysms in various regions of the cerebral vasculature, but is only approved for use in the internal carotid arteries. Treatment of distal PICA aneurysms with P…
View article: Impact of Acute and Persistent Excitation of Prelimbic Pyramidal Neurons on Motor Activity and Trace Fear Learning
Impact of Acute and Persistent Excitation of Prelimbic Pyramidal Neurons on Motor Activity and Trace Fear Learning Open
Drug-induced neuroadaptations in the mPFC have been implicated in addictive behaviors. Repeated cocaine exposure has been shown to increase pyramidal neuron excitability in the prelimbic (PL) region of the mouse mPFC, an adaptation attribu…
View article: BIOM-41. GENETIC MARKERS CORRELATED WITH PROGRESSION-FREE SURVIVAL TIMES IN GLIOBLASTOMA PATIENTS UNDERGOING TREATMENT WITH TUMOR TREATING FIELDS
BIOM-41. GENETIC MARKERS CORRELATED WITH PROGRESSION-FREE SURVIVAL TIMES IN GLIOBLASTOMA PATIENTS UNDERGOING TREATMENT WITH TUMOR TREATING FIELDS Open
INTRODUCTION Despite advances in surgical approaches, followed by chemo-radiotherapy protocols, the overall prognosis for patients with glioblastoma remains poor. Clinical trials have demonstrated that the use of low intensity alternating …
View article: QOLP-13. COMPARISON OF SYMPTOM BURDEN AND ASSOCIATED IMPACT ON DAILY LIFE IN GLIOBLASTOMA PATIENTS TREATED WITH AND WITHOUT TUMOR TREATING FIELDS
QOLP-13. COMPARISON OF SYMPTOM BURDEN AND ASSOCIATED IMPACT ON DAILY LIFE IN GLIOBLASTOMA PATIENTS TREATED WITH AND WITHOUT TUMOR TREATING FIELDS Open
INTRODUCTION Clinical trials have demonstrated that the use of low intensity alternating electric fields, known as Tumor Treating Fields (TTFields), via the Optune™ device extends overall survival times in patients with glioblastoma when c…
View article: INNV-15. COMPARISON OF READIBAND™ ACTIGRAPH AND ASSOCIATED SLEEP/WAKE CLASSIFICATION ALGORITHMS WITH PATIENT-REPORTED SLEEP QUALITY AND FATIGUE IN GLIOBLASTOMA
INNV-15. COMPARISON OF READIBAND™ ACTIGRAPH AND ASSOCIATED SLEEP/WAKE CLASSIFICATION ALGORITHMS WITH PATIENT-REPORTED SLEEP QUALITY AND FATIGUE IN GLIOBLASTOMA Open
INTRODUCTION Fatigue and sleep disturbances are among the most common side-effects reported by patients with glioblastoma and contribute significantly to the quality-of-life for this population. Non-invasive monitoring of long-term sleep p…
View article: Divergent behavioral consequences of manipulations enhancing pyramidal neuron excitability in the prelimbic cortex
Divergent behavioral consequences of manipulations enhancing pyramidal neuron excitability in the prelimbic cortex Open
Background Drug-induced neuroadaptations in the prefrontal cortex are thought to underlie impaired executive functions that reinforce addictive behaviors. Repeated cocaine exposure increased layer 5/6 pyramidal neuron excitability in the m…
View article: INNV-08. VALIDATION OF READIBAND™ ACTIGRAPH AND ASSOCIATED SLEEP/WAKE CLASSIFICATION ALGORITHMS IN PREDICTING CANCER-RELATED FATIGUE IN HIGH GRADE GLIOBLASTOMA
INNV-08. VALIDATION OF READIBAND™ ACTIGRAPH AND ASSOCIATED SLEEP/WAKE CLASSIFICATION ALGORITHMS IN PREDICTING CANCER-RELATED FATIGUE IN HIGH GRADE GLIOBLASTOMA Open
INTRODUCTION Standard care for glioblastoma consists of maximal surgical resection followed by radiotherapy with concurrent and adjuvant temozolomide. Fatigue and sleep disturbances are among the most common side-effect reported by these p…
View article: INNV-12. OUTCOMES IN A REAL-WORLD PRACTICE FOR PATIENTS WITH PRIMARY GLIOBLASTOMA: IMPACT OF A SPECIALIZED NEURO-ONCOLOGY CANCER CARE PROGRAM
INNV-12. OUTCOMES IN A REAL-WORLD PRACTICE FOR PATIENTS WITH PRIMARY GLIOBLASTOMA: IMPACT OF A SPECIALIZED NEURO-ONCOLOGY CANCER CARE PROGRAM Open
INTRODUCTION Standard care for newly diagnosed glioblastoma consists of maximal surgical resection followed by radiotherapy with concurrent and adjuvant temozolomide. Prognosis for glioblastoma still remains poor, with a reported median su…
View article: QOLP-10. PATIENT-REPORTED OUTCOMES DURING TREATMENT FOR GLIOBLASTOMA: SYMPTOM BURDEN AND ASSOCIATED IMPACT ON DAILY LIFE
QOLP-10. PATIENT-REPORTED OUTCOMES DURING TREATMENT FOR GLIOBLASTOMA: SYMPTOM BURDEN AND ASSOCIATED IMPACT ON DAILY LIFE Open
INTRODUCTION Glioblastoma is the most common primary malignant brain tumor, with an annual incidence of 3–4 new cases per 100,000 people. Despite advances in chemotherapy, radiotherapy, and surgical interventions, prognosis remains poor. A…
View article: Weekday Versus Weekend Presentation in the Acute Management of Ischemic Stroke Through Telemedicine
Weekday Versus Weekend Presentation in the Acute Management of Ischemic Stroke Through Telemedicine Open
A “weekend effect” resulting in higher mortality rates for patients with stroke admitted on weekends has been reported. We examine this phenomenon for patients with acute ischemic stroke (AIS) presenting to telestroke (TS) sites to determi…
View article: Inhibition of Pyramidal Neurons in the Basal Amygdala Promotes Fear Learning
Inhibition of Pyramidal Neurons in the Basal Amygdala Promotes Fear Learning Open
The basolateral amygdala complex, which contains the lateral (LA) and basal (BA) subnuclei, is a critical substrate of associative learning related to reward and aversive stimuli. Auditory fear conditioning studies in rodents have shown th…
View article: GIRK2 splice variants and neuronal G protein-gated K+ channels: implications for channel function and behavior
GIRK2 splice variants and neuronal G protein-gated K+ channels: implications for channel function and behavior Open
View article: Identification and characterization of heptapeptide modulators of the glycine receptor
Identification and characterization of heptapeptide modulators of the glycine receptor Open
View article: G Protein‐Gated Inwardly Rectifying Potassium Channel Subunit 3 Knock‐Out Mice Show Enhanced Ethanol Reward
G Protein‐Gated Inwardly Rectifying Potassium Channel Subunit 3 Knock‐Out Mice Show Enhanced Ethanol Reward Open
Background G protein‐gated inwardly rectifying potassium ( GIRK ) channels contribute to the effects of a number of drugs of abuse, including ethanol. However, the roles of individual subunits in the rewarding effects of ethanol are poorly…
View article: Acute Ethanol Withdrawal Impairs Contextual Learning and Enhances Cued Learning
Acute Ethanol Withdrawal Impairs Contextual Learning and Enhances Cued Learning Open
Background Alcohol affects many of the brain regions and neural processes that support learning and memory, and these effects are thought to underlie, at least in part, the development of addiction. Although much work has been done regardi…