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View article: Aryl hydrocarbon receptor interacting protein and syndromic gene variants detected in Turkish isolated pituitary adenoma families by whole exome sequencing
Aryl hydrocarbon receptor interacting protein and syndromic gene variants detected in Turkish isolated pituitary adenoma families by whole exome sequencing Open
Genetic causes of familial isolated pituitary adenomas (FIPAs) remain mostly elusive. A cohort of 20 FIPA cases from 12 different geographical regions of Türkiye was included to characterize clinical and genetic features. Whole exome seque…
View article: CDKN1B Mutation Analyses and Biochemical Characteristics in Patients with Symptomatic or asymptomatic Primary Hyperparathyroidism: A Prospective Single-Centre Study
CDKN1B Mutation Analyses and Biochemical Characteristics in Patients with Symptomatic or asymptomatic Primary Hyperparathyroidism: A Prospective Single-Centre Study Open
Background: The clinical phenotype of PHPT changed from overt bone and renal involvement to asymptomatic hypercalcaemia. Patients with symptomatic hyperparathyroidism should be referred for surgery, and asymptomatic patients’ management ha…
View article: Addison’s Crisis or Momordica Charantia Extract: Which Caused Shock?
Addison’s Crisis or Momordica Charantia Extract: Which Caused Shock? Open
Aim: Addison’s crisis is extremely rare entity that is difficult to diagnose in the emergency department. Here we present a case of Addison’s crisis diagnosed in the emergency department who complained of vomiting after consuming extract o…
View article: Evaluation of Serum Irisin Levels in Patients Developing Nephropathy Due to Type 2 Diabetes Mellitus
Evaluation of Serum Irisin Levels in Patients Developing Nephropathy Due to Type 2 Diabetes Mellitus Open
Objective: Type 2 diabetes mellitus is a metabolic disease characterized by multi-organ involvement, mostly the renal system, as a result of impaired blood sugar regulation.Damage to the renal system can be serious and can be noticed late.…
View article: Inadequate Gonadal Replacement in Patients with Turner Syndrome may Result in Pituitary Volume Enlargement
Inadequate Gonadal Replacement in Patients with Turner Syndrome may Result in Pituitary Volume Enlargement Open
Objectives: Patients with Turner syndrome need hormone replacement therapy for puberty induction. However, it is not known whether inadequate hormone replacement therapy affects the pituitary. Material and Methods: Patients with Turner syn…
View article: Turkish Journal of Endocrinology and Metabolism
Turkish Journal of Endocrinology and Metabolism Open
Distant metastasis may be the initial sign of differentiated thyroid carcinoma in rare cases. In this instance, the treatment approach is usually individualized. Unlike most other cancers, local treatment of the primary tumor (total thyroi…
View article: A rare cause of hypocalcemia: Pseudohypoparathyroidism
A rare cause of hypocalcemia: Pseudohypoparathyroidism Open
Pseudohypoparathyroidism is a rare inherited metabolic disorder that associated with parathormone resistance. Low serum calcium, high phosphates and raised parathormone levels suggesting parathormone resistance are biochemical characterist…
View article: Awareness of Vaccination against Respiratory Tract Diseases, Including Pneumonia, Influenza, and COVID‐19 in Patients with Diabetes Mellitus
Awareness of Vaccination against Respiratory Tract Diseases, Including Pneumonia, Influenza, and COVID‐19 in Patients with Diabetes Mellitus Open
Patients with diabetes have an increased risk of severe acute respiratory infections, and vaccination is their life‐saving option. This study aimed to investigate the interest and knowledge of patients about influenza, pneumonia, and COVID…
View article: Comparison of iodine deficiency, thyroid volume increase, and the presence of thyroid nodules in patients with type 2 diabetes mellitus and metabolic syndrome and healthy controls
Comparison of iodine deficiency, thyroid volume increase, and the presence of thyroid nodules in patients with type 2 diabetes mellitus and metabolic syndrome and healthy controls Open
Amaç: Bu çalışmada, Çukurova Bölgesi’nde yaşayan insanlarda iyot tayini, iyotlu tuz kullanım oranını ve bu parametrelerle tiroid volümü ve tiroid nodülü arasında ilişki olup olmadığını, ayrıca Tip 2 Diyabetes Mellitus (T2DM) ve Metabolik S…
View article: Pituitary Volume in Patients with Primary Empty Sella and Clinical Relevance to Pituitary Hormone Secretion: A Retrospective Single Center Study
Pituitary Volume in Patients with Primary Empty Sella and Clinical Relevance to Pituitary Hormone Secretion: A Retrospective Single Center Study Open
Background: According to neuroradiological findings, empty sella seems to be deprived of pituitary tissue in sella turcica. Changing size of the pituitary volume is closely related to the occurrence of primary empty sella. The aim of the s…
View article: Clinical, hormonal, radiological and morphological comparison of patients with clinically evident Cushing's disease and patients with silent corticotroph cell adenoma
Clinical, hormonal, radiological and morphological comparison of patients with clinically evident Cushing's disease and patients with silent corticotroph cell adenoma Open
Purpose: The aim of the study was to review our clinical 7 years experiences with silent corticotroph adenoma (SCA) and Cushing disease (CD) with regard to clinical, radiological features, immunohistochemical and surgical outcomes and comp…
View article: Possible Role of Advanced Glycation End Products (AGEs) In the Clinical Course of Prostate Neoplasies Among Patients with and without Type 2 Diabetes Mellitus
Possible Role of Advanced Glycation End Products (AGEs) In the Clinical Course of Prostate Neoplasies Among Patients with and without Type 2 Diabetes Mellitus Open
Aim: The cognate receptor expression of AGE (RAGE; receptor for AGE) on malignant tissues in diabetic patients has been suggested as a co-factor in determining the clinical course and prognosis. We aimed to search this relationship between…
View article: Zoledronic acid improves bone mineral density in β-thalassemia patients with osteoporosis: a case control study
Zoledronic acid improves bone mineral density in β-thalassemia patients with osteoporosis: a case control study Open
Purpose: This study addresses the efficacy of zoledronic acid treatment in osteoporotic patients with β-thalassemia.Materials and Methods: Thirty-nine thalassemic patients were enrolled in this study. Bone mineral density was measured usin…
View article: Diabetic Foot Wounds: Which Patients are More Prone to Tetanus?
Diabetic Foot Wounds: Which Patients are More Prone to Tetanus? Open
Introduction: Patients who have tetanus-prone wounds, diabetes mellitus, or chronic wounds are more likely to contract tetanus. In this study, we aimed to evaluate the tetanus immunization status of patients with diabetic foot wounds (DFW)…
View article: Effect of Vitamin D Treatment on Glycemic Control, Diastolic Functions, and Carotid Intima-Media Thickness in Patients with Type 2 Diabetes Mellitus
Effect of Vitamin D Treatment on Glycemic Control, Diastolic Functions, and Carotid Intima-Media Thickness in Patients with Type 2 Diabetes Mellitus Open
Objective: The purpose of this study was to investigate the influence of 25(OH)D3 levels on glycemic control, diastolic functions, and carotid intima-media thickness in patients with Type 2 diabetes mellitus. Material and Methods: Patients…
View article: Diagnostic efficacy of 18F-FDG PET/CT in patients with adrenal incidentaloma
Diagnostic efficacy of 18F-FDG PET/CT in patients with adrenal incidentaloma Open
Background The management of adrenal incidentaloma is still a challenge with respect to determining its functionality (hormone secretion) and malignancy. In this light, we performed 18 F-FDG PET/CT scan to assess the SUV max values in diff…
View article: Evaluation of Clinical and Microbiological Characteristics of Foot Infections of Patients With Diabetes: Does Antibiotic Susceptibility Change?
Evaluation of Clinical and Microbiological Characteristics of Foot Infections of Patients With Diabetes: Does Antibiotic Susceptibility Change? Open
Background: The aim of the present study was to evaluate microorganisms isolated from foot ulcers of patients with diabetes, resistance profile and establish their relationship with amputation. Methods: The study included 51 patients…
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View article: Evaluation of Clinical and Microbiological Characteristics of Foot Infections of Patients With Diabetes: Does Antibiotic Susceptibility Change?
Evaluation of Clinical and Microbiological Characteristics of Foot Infections of Patients With Diabetes: Does Antibiotic Susceptibility Change? Open
Background: The aim of the present study was to evaluate microorganisms isolated from foot ulcers of patients with diabetes, resistance profile and establish their relationship with amputation. Methods: The study included 51 patients with …
View article: Multidisciplinary approach for patients with functional and non‐functional adrenal masses and review of the literature
Multidisciplinary approach for patients with functional and non‐functional adrenal masses and review of the literature Open
Background Adrenal incidentalomas are adrenal masses that are discovered by imaging tests performed for other reasons. Aims In this retrospective study, we analysed 229 Turkish patients with adrenal masses and who presented with or without…
View article: Diabetic Foot Wounds: Which Patients are More Prone to Tetanus?
Diabetic Foot Wounds: Which Patients are More Prone to Tetanus? Open
Patients who have diabetes and chronic wounds are more prone to tetanus than the other populations. The prevalence of diabetes among patients diagnosed with tetanus was 15%, nearly three times the average expected prevalence of diabetes in…
View article: General approach to adrenal incidentalomas with regards to a case with subclinical Cushing syndrome
General approach to adrenal incidentalomas with regards to a case with subclinical Cushing syndrome Open
Adrenal insidentalomalar başka nedenlerle yapılan görüntüleme testleri sırasında saptanan lezyonlardır. Günümüzde abdominal görüntüleme tekniklerinin yaygın olarak kullanılmaya başlanması ile birlikte adrenal insidentaloma tanısının sıklığ…
View article: Carotid Intima-Media Thickness as the Cardiometabolic Risk Indicator in Patients with Nonfunctional Adrenal Mass and Metabolic Syndrome Screening
Carotid Intima-Media Thickness as the Cardiometabolic Risk Indicator in Patients with Nonfunctional Adrenal Mass and Metabolic Syndrome Screening Open
We found that the increased insulin resistance, increased risk of cardiovascular disease with the increase in the thickness of carotid intima-media and diastolic disfunction parameters, although the patients with adrenal incidentaloma are …
View article: Metabolic evaluation and measurement of ovarian volume in polycystic ovary sydrome: a cross-sectional observational study
Metabolic evaluation and measurement of ovarian volume in polycystic ovary sydrome: a cross-sectional observational study Open
Purpose: Polycystic ovary sydrome is a disease of women in reproductive period, with hirsutism or hyperandrogenic signs in laboratory evaluation, causing infertility due to dysmenorrhea and unovulation. Accompanying insulin resistance and …
View article: Spontaneous calcaneal fracture in patients with diabetic foot ulcer: Four cases report and review of literature
Spontaneous calcaneal fracture in patients with diabetic foot ulcer: Four cases report and review of literature Open
Spontaneous calcaneal fractures in diabetic patients without obvious trauma may occur, sometimes accompanying diabetic foot ulcers. In the current study we report four cases who were hospitalized for diabetic foot ulcer with concomitant ca…