Mei‐Fong Ho
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View article: A CAF01-adjuvanted whole asexual blood-stage liposomal malaria vaccine induces a CD4 <sup>+</sup> T-cell-dependent strain-transcending protective immunity in rodent models
A CAF01-adjuvanted whole asexual blood-stage liposomal malaria vaccine induces a CD4 <sup>+</sup> T-cell-dependent strain-transcending protective immunity in rodent models Open
Malaria is a leading cause of illness and death in children under 5 years of age in Sub-Saharan Africa. Currently, there is no highly efficacious malaria vaccine capable of inducing long-lasting immunity. This has increased interest in exp…
View article: Investigation of liposomal self-adjuvanting peptide epitopes derived from conserved blood-stage Plasmodium antigens
Investigation of liposomal self-adjuvanting peptide epitopes derived from conserved blood-stage Plasmodium antigens Open
Malaria is a vector born parasitic disease causing millions of deaths every year. Despite the high mortality rate, an effective vaccine against this mosquito-borne infectious disease is yet to be developed. Up to date, RTS,S/AS01 is the on…
View article: Investigation of liposomal self-adjuvanting peptide epitopes derived from conserved blood-stage Plasmodium antigens
Investigation of liposomal self-adjuvanting peptide epitopes derived from conserved blood-stage Plasmodium antigens Open
Malaria is a vector born parasitic disease causing millions of deaths every year. Despite the high mortality rate, an effective vaccine against this mosquito-borne infectious disease is yet to be developed. Up to date, RTS,S/AS01 is the on…
View article: Development and Evaluation of a Cryopreserved Whole-Parasite Vaccine in a Rodent Model of Blood-Stage Malaria
Development and Evaluation of a Cryopreserved Whole-Parasite Vaccine in a Rodent Model of Blood-Stage Malaria Open
Malaria is a mosquito-borne infectious disease that is caused by parasites of the genus, Plasmodium . There are seven different Plasmodium spp. that can cause malaria in humans, with P. falciparum causing the majority of the morbidity and …
View article: Research Global sequence variation in the histidine-rich proteins 2 and 3 of Plasmodium falciparum: implications for the performance of malaria rapid diagnostic tests
Research Global sequence variation in the histidine-rich proteins 2 and 3 of Plasmodium falciparum: implications for the performance of malaria rapid diagnostic tests Open
BACKGROUND: Accurate diagnosis is essential for prompt and appropriate treatment of malaria. While rapid diagnostic tests (RDTs) offer great potential to improve malaria diagnosis, the sensitivity of RDTs has been reported to be highly var…
View article: Mannosylated liposomes formulated with whole parasite P. falciparum blood-stage antigens are highly immunogenic in mice
Mannosylated liposomes formulated with whole parasite P. falciparum blood-stage antigens are highly immunogenic in mice Open
View article: Controlled Infection Immunization Using Delayed Death Drug Treatment Elicits Protective Immune Responses to Blood-Stage Malaria Parasites
Controlled Infection Immunization Using Delayed Death Drug Treatment Elicits Protective Immune Responses to Blood-Stage Malaria Parasites Open
Naturally acquired immunity to malaria is robust and protective against all strains of the same species of Plasmodium . This develops as a result of repeated natural infection, taking several years to develop.
View article: Vaccination with chemically attenuated Plasmodium falciparum asexual blood-stage parasites induces parasite-specific cellular immune responses in malaria-naïve volunteers: a pilot study
Vaccination with chemically attenuated Plasmodium falciparum asexual blood-stage parasites induces parasite-specific cellular immune responses in malaria-naïve volunteers: a pilot study Open
View article: Streptococcal Immunity Is Constrained by Lack of Immunological Memory following a Single Episode of Pyoderma
Streptococcal Immunity Is Constrained by Lack of Immunological Memory following a Single Episode of Pyoderma Open
The immunobiology underlying the slow acquisition of skin immunity to group A streptococci (GAS), is not understood, but attributed to specific virulence factors impeding innate immunity and significant antigenic diversity of the type-spec…
View article: Prenatal ethanol exposure alters adult hippocampal VGLUT2 expression with concomitant changes in promoter DNA methylation, H3K4 trimethylation and miR-467b-5p levels
Prenatal ethanol exposure alters adult hippocampal VGLUT2 expression with concomitant changes in promoter DNA methylation, H3K4 trimethylation and miR-467b-5p levels Open