Mei‐chen Wan
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View article: Platelet methyltransferase-like protein 4-mediated mitochondrial DNA metabolic disorder exacerbates oral mucosal immunopathology in hypoxia
Platelet methyltransferase-like protein 4-mediated mitochondrial DNA metabolic disorder exacerbates oral mucosal immunopathology in hypoxia Open
View article: DNA-collagen dressing for promoting scarless healing in early burn wound management
DNA-collagen dressing for promoting scarless healing in early burn wound management Open
In the early stages of healing severe burn wounds, increased exudate and immune dysregulation heighten the risk of scar formation. Current dressings for severe burns present significant challenges and are inadequate in effectively managing…
View article: Metabolic support protects oral mucosa from ferroptosis in radiation-induced mucositis
Metabolic support protects oral mucosa from ferroptosis in radiation-induced mucositis Open
Ionizing radiation is effective in combating cancer but inflicts severe damage on the oral mucosa. The mechanisms behind this damage remain unclear, and current treatment modalities are primarily palliative. This study revealed that ferrop…
View article: Effect of regional crosstalk between sympathetic nerves and sensory nerves on temporomandibular joint osteoarthritic pain
Effect of regional crosstalk between sympathetic nerves and sensory nerves on temporomandibular joint osteoarthritic pain Open
Temporomandibular joint osteoarthritis (TMJ-OA) is a common disease often accompanied by pain, seriously affecting physical and mental health of patients. Abnormal innervation at the osteochondral junction has been considered as a predomin…
View article: Effect of regional crosstalk between sympathetic nerves and sensory nerves on temporomandibular joint osteoarthritic pain
Effect of regional crosstalk between sympathetic nerves and sensory nerves on temporomandibular joint osteoarthritic pain Open
Temporomandibular joint osteoarthritis (TMJ-OA) is a common disease often accompanied by pain, seriously affecting physical and mental health of patients. Abnormal innervation at the osteochondral junction has been considered as a predomin…
View article: Atypical artificial cells: Novel biomimetic materials for combating cancer
Atypical artificial cells: Novel biomimetic materials for combating cancer Open
The functional concept of using synthetic entities to supplement or replace certain functions or structures of biological cells is realized by the development of atypical artificial cells using a bottom‐up approach. Tremendous progress has…
View article: Recent advances in the pathogenesis and prevention strategies of dental calculus
Recent advances in the pathogenesis and prevention strategies of dental calculus Open
Dental calculus severely affects the oral health of humans and animal pets. Calculus deposition affects the gingival appearance and causes inflammation. Failure to remove dental calculus from the dentition results in oral diseases such as …
View article: Publisher Correction: Bacteria-mediated resistance of neutrophil extracellular traps to enzymatic degradation drives the formation of dental calculi
Publisher Correction: Bacteria-mediated resistance of neutrophil extracellular traps to enzymatic degradation drives the formation of dental calculi Open
View article: Bacteria-mediated resistance of neutrophil extracellular traps to enzymatic degradation drives the formation of dental calculi
Bacteria-mediated resistance of neutrophil extracellular traps to enzymatic degradation drives the formation of dental calculi Open
Dental calculi can cause gingival bleeding and periodontitis, yet the mechanism underlying the formation of such mineral build-ups, and in particular the role of the local microenvironment, are unclear. Here we show that the formation of d…
View article: Extracellular DNA as potential contributors to pathological calcification
Extracellular DNA as potential contributors to pathological calcification Open
Some biomolecules involved in pathological calcification have been identified. However, the exact mechanism in which this intricate process occurs remains unknown. Extracellular DNA (exDNA) has recently been recognized as a partaker in thi…
View article: Regulatory mechanisms and regeneration strategies of the soft–hard tissue interface in the human periodontium
Regulatory mechanisms and regeneration strategies of the soft–hard tissue interface in the human periodontium Open
The soft‐hard tissue interface of the human periodontium is responsible for periodontal homeostasis and is essential for normal oral activities. This soft‐hard tissue interface is formed by the direct insertion of fibrous ligaments into th…
View article: Fibrocyte: a missing piece in the pathogenesis of fibrous epulis
Fibrocyte: a missing piece in the pathogenesis of fibrous epulis Open
Objective To investigate the significant role of fibrocytes in pathogenesis of fibrous epulis. Material Human epulis specimens and human peripheral blood mononuclear cells (PBMCs) were used in this study. Methods Different subtypes of huma…
View article: How How to Use Graph Theory Benefiting the Neighborhoods Environment
How How to Use Graph Theory Benefiting the Neighborhoods Environment Open
Graph Theory is a popular field with wide applications. It also has the reputation of being the type of math that is more up-to-date with modern times. However, a quick search of the math curriculum at the secondary level will show a strik…
View article: Engineered extracellular vesicles: Regulating the crosstalk between the skeleton and immune system
Engineered extracellular vesicles: Regulating the crosstalk between the skeleton and immune system Open
View article: Extracellular DNA: A Missing Link in the Pathogenesis of Ectopic Mineralization
Extracellular DNA: A Missing Link in the Pathogenesis of Ectopic Mineralization Open
Although deoxyribonucleic acid (DNA) is the genetic coding for the very essence of life, these macromolecules or components thereof are not necessarily lost after a cell dies. There appears to be a link between extracellular DNA and biomin…
View article: Extracellular DNA: A Missing Link in the Pathogenesis of Ectopic Mineralization (Adv. Sci. 5/2022)
Extracellular DNA: A Missing Link in the Pathogenesis of Ectopic Mineralization (Adv. Sci. 5/2022) Open
Extracellular DNA In article number 2103693, Li‐na Niu and co‐workers discuss a fascinating novel function of extracellular DNA as mineralization initiators in ectopic calcification. Extracellular DNAs regulate matrix calcification outside…
View article: Extracellular DNA: A Missing Link in the Pathogenesis of Ectopic Mineralization
Extracellular DNA: A Missing Link in the Pathogenesis of Ectopic Mineralization Open
Although deoxyribonucleic acid (DNA) is the genetic coding for the very essence of life, these macromolecules or components thereof are not necessarily lost after a cell dies. There appears to be a link between extracellular DNA and biomin…