Meifen Zhang
YOU?
Author Swipe
View article: Therapeutic drug monitoring plays an important role in patients with noninfectious uveitis receiving adalimumab
Therapeutic drug monitoring plays an important role in patients with noninfectious uveitis receiving adalimumab Open
Objective To evaluate the association between serum adalimumab (ADA) concentrations, antibodies against adalimumab (AAAs), tumor necrosis factor α (TNFα) levels, and clinical response in patients with noninfectious uveitis (NIU), as well a…
View article: Clinical guidelines for the diagnosis and treatment of vitreoretinal lymphoma in Chinese patients (2024)
Clinical guidelines for the diagnosis and treatment of vitreoretinal lymphoma in Chinese patients (2024) Open
Vitreoretinal lymphoma (VRL) is often a diffuse large B-cell lymphoma in nature, and patients may have or eventually develop central nervous system lymphoma, which frequently leads to a poor prognosis. Currently, there are no international…
View article: Relapses and outcomes of systemic chemo-free therapies combined with intravitreous methotrexate in isolated primary vitreoretinal lymphoma: an analysis based on two prospective cohort studies
Relapses and outcomes of systemic chemo-free therapies combined with intravitreous methotrexate in isolated primary vitreoretinal lymphoma: an analysis based on two prospective cohort studies Open
View article: Incorporating a dynamic extraocular muscle simulation model into the undergraduate ophthalmic curriculum
Incorporating a dynamic extraocular muscle simulation model into the undergraduate ophthalmic curriculum Open
View article: Decreased expression of the immune checkpoint regulator <scp>VISTA</scp> on neutrophils correlates with disease activity in autoimmune uveitis
Decreased expression of the immune checkpoint regulator <span>VISTA</span> on neutrophils correlates with disease activity in autoimmune uveitis Open
Immune checkpoint V‐domain Ig suppressor of T‐cell activation (VISTA) exhibits distinct expression patterns and non‐redundant immunoregulatory mechanisms in different autoimmune diseases. This study aims to investigate the expression of VI…
View article: The application of flipped classroom to teaching diabetic retinopathy and glaucoma in ophthalmology undergraduate education: a randomized study
The application of flipped classroom to teaching diabetic retinopathy and glaucoma in ophthalmology undergraduate education: a randomized study Open
View article: Multiple cytokine analysis of aqueous humor in uveitis with or without secondary glaucoma
Multiple cytokine analysis of aqueous humor in uveitis with or without secondary glaucoma Open
To assess the level of both pro-inflammatory and anti-inflammatory cytokines in the aqueous humor (AH) of patients suffering from uveitis, with or without coexisting glaucoma, and compare them with patients diagnosed with primary open-angl…
View article: Quantitative urinary proteome analysis reveals potential biomarkers for disease activity of Behcet’s disease uveitis
Quantitative urinary proteome analysis reveals potential biomarkers for disease activity of Behcet’s disease uveitis Open
View article: Author Correction: Identification of an intraocular microbiota
Author Correction: Identification of an intraocular microbiota Open
View article: Risk factors and their interactive effects on severe acute pancreatitis complicated with acute gastrointestinal injury
Risk factors and their interactive effects on severe acute pancreatitis complicated with acute gastrointestinal injury Open
Tumour rupture of gastrointestinal stromal tumours (GISTs) has been considered to be a remarkable risk factor because of its unfavourable impact on the oncological outcome. Although tumour rupture has not yet been included in the current t…
View article: Proton-pump inhibitor use amongst patients with severe hypomagnesemia
Proton-pump inhibitor use amongst patients with severe hypomagnesemia Open
Introduction: Long-term proton pump inhibitor (PPI) use has been associated with hypomagnesemia. It is unknown how frequently PPI use is implicated in patients with severe hypomagnesemia, and its clinical course or risk factors. Methods: A…
View article: Corrigendum: Circulating cell-free DNA and IL-10 from cerebrospinal fluids aid primary vitreoretinal lymphoma diagnosis
Corrigendum: Circulating cell-free DNA and IL-10 from cerebrospinal fluids aid primary vitreoretinal lymphoma diagnosis Open
[This corrects the article DOI: 10.3389/fonc.2022.955080.].
View article: Cell-Free DNA in Cerebrospinal Fluid Complements the Monitoring Value of Interleukin-10 in Newly Diagnosed Primary Central Nervous System Lymphoma
Cell-Free DNA in Cerebrospinal Fluid Complements the Monitoring Value of Interleukin-10 in Newly Diagnosed Primary Central Nervous System Lymphoma Open
Objectives. Primary central nervous system lymphoma (PCNSL) usually has a poor prognosis. Cerebrospinal fluid (CSF) interleukin (IL)-10 has shown diagnostic, prognostic, and monitoring value in our previous studies. Cell-free circulating t…
View article: Efficacy and safety of adalimumab for inflammatory flare prevention in paediatric non-infectious anterior uveitis with peripheral retinal vascular leakage: a study protocol for a single-centre, randomised controlled trial
Efficacy and safety of adalimumab for inflammatory flare prevention in paediatric non-infectious anterior uveitis with peripheral retinal vascular leakage: a study protocol for a single-centre, randomised controlled trial Open
Introduction Paediatric patients with chronic anterior uveitis are more prone to suffer from the chronic course of intraocular inflammation and adverse effects of long-term immunomodulatory therapy, either topical glucocorticosteroids or s…
View article: There Is No Evidence That Inactivated COVID-19 Vaccines Increase Risks of Uveitis Flare
There Is No Evidence That Inactivated COVID-19 Vaccines Increase Risks of Uveitis Flare Open
This is a retrospective study to investigate the impact of inactivated Coronavirus disease-2019 (COVID-19) vaccination on uveitis flare in patients with uveitis. Sixty patients that were regularly followed up for uveitis for at least two m…
View article: The safety and efficacy of CO 2 laser-assisted sclerectomy surgery-based multi- pathway glaucoma surgery in intractable pediatric glaucoma
The safety and efficacy of CO 2 laser-assisted sclerectomy surgery-based multi- pathway glaucoma surgery in intractable pediatric glaucoma Open
Background To evaluate the safety and efficacy of CO 2 laser-assisted sclerectomy surgery (CLASS)-based multi-pathway glaucoma surgeries in intractable pediatric glaucoma. Methods Retrospective, self-controlled, interventional case series.…
View article: Circulating cell-free DNA and IL-10 from cerebrospinal fluids aid primary vitreoretinal lymphoma diagnosis
Circulating cell-free DNA and IL-10 from cerebrospinal fluids aid primary vitreoretinal lymphoma diagnosis Open
Primary vitreoretinal lymphoma (PVRL) is a rare variant of primary central nervous system lymphoma (PCNSL) that presents diagnostic challenges. Here, we focused on circulating cell-free DNA (cfDNA) and interleukin-10 (IL-10) isolated from …
View article: Methotrexate for chronic non-necrotizing anterior scleritis in Chinese patients
Methotrexate for chronic non-necrotizing anterior scleritis in Chinese patients Open
AIM: To evaluate the effectiveness and corticosteroid-sparing capabilities of methotrexate (MTX) in the treatment of chronic non-necrotizing anterior scleritis in Chinese patients. METHODS: A retrospective chart review of all patients with…
View article: Treatment of Primary Aldosteronism and Reversal of Renin Suppression Improves Left Ventricular Systolic Function
Treatment of Primary Aldosteronism and Reversal of Renin Suppression Improves Left Ventricular Systolic Function Open
Introduction Primary aldosteronism (PA) is associated with increased risk of cardiovascular events. However, treatment of PA has not been shown to improve left ventricular (LV) systolic function using the conventional assessment with LV ej…
View article: Primary Aldosteronism More Prevalent in Patients With Cardioembolic Stroke and Atrial Fibrillation
Primary Aldosteronism More Prevalent in Patients With Cardioembolic Stroke and Atrial Fibrillation Open
Background Primary aldosteronism (PA) is the most common cause of secondary hypertension, and patients are at an increased risk of atrial fibrillation (AF) and stroke. We assessed the prevalence of PA in patients with recent stroke. Method…
View article: The Efficacy and Safety of Adalimumab in Treating Pediatric Noninfectious Chronic Anterior Uveitis With Peripheral Retinal Vascular Leakage: A Pilot Study
The Efficacy and Safety of Adalimumab in Treating Pediatric Noninfectious Chronic Anterior Uveitis With Peripheral Retinal Vascular Leakage: A Pilot Study Open
Purpose This study is aimed to assess the efficacy of adalimumab in alleviating peripheral vascular leakage in pediatric chronic anterior uveitis patients, along with its ability to improve best-corrected visual acuity (BCVA) and inflammat…
View article: Case Report: Intraocular Hemorrhage in a Primary Vitreoretinal Lymphoma Patient Treated With Zanubrutinib
Case Report: Intraocular Hemorrhage in a Primary Vitreoretinal Lymphoma Patient Treated With Zanubrutinib Open
Purpose To report a case of primary vitreoretinal lymphoma (PVRL) treated with oral zanubrutinib, who had bilateral intraocular hemorrhage after intravitreal injection of methotrexate (MTX). Case report A 69-year-old Chinese female present…
View article: Hyperaldosteronism
Hyperaldosteronism Open
While most patients with hypertension have no underlying cause and require lifelong medications, 5–10% have the treatable condition of primary aldosteronism. In primary aldosteronism, the adrenal glands overproduce the hormone aldosterone,…
View article: Efficacy and safety of non-penetrating glaucoma surgery with phacoemulsification versus non-penetrating glaucoma surgery: a Meta-analysis
Efficacy and safety of non-penetrating glaucoma surgery with phacoemulsification versus non-penetrating glaucoma surgery: a Meta-analysis Open
AIM: To compare the clinical efficacy and safety of non-penetrating glaucoma surgery (NPGS) plus phacoemulsification (Phaco-NPGS) and NPGS-alone. METHODS: We systematically searched various databases and reviewed studies that had evaluated…
View article: Assessment of Macular Capillary Perfusion by Optical Coherence Tomography Angiography on Quiescent Unilateral Anterior Pediatric Uveitis
Assessment of Macular Capillary Perfusion by Optical Coherence Tomography Angiography on Quiescent Unilateral Anterior Pediatric Uveitis Open
Purpose: Using spectral domain optical coherence tomography angiography (SD-OCTA) to evaluate tomographic and microvascular parameters in the macula in quiescent unilateral anterior pediatric uveitis (APU) patients.Methods: Forty-two eyes …
View article: Widefield Swept-Source Optical Coherence Tomography Angiography Assessment of Choroidal Changes in Vogt-Koyanagi-Harada Disease
Widefield Swept-Source Optical Coherence Tomography Angiography Assessment of Choroidal Changes in Vogt-Koyanagi-Harada Disease Open
Purpose: To investigate choroidal changes in patients with Vogt-Koyanagi-Harada disease (VKH) using widefield swept-source optical coherence tomography angiography (SS-OCTA). Methods: In this cross-sectional study, 133 eyes of 69 patients …
View article: Tolerability and Efficacy of Long-Term Medical Therapy in Primary Aldosteronism
Tolerability and Efficacy of Long-Term Medical Therapy in Primary Aldosteronism Open
Introduction Patients with primary aldosteronism (PA) have increased cardiovascular risk, and there are concerns about the efficacy of medical therapy. Objective We aimed to assess long-term tolerability and efficacy of medical therapy in …
View article: Anti-interleukin 6 receptor antibody tocilizumab was not satisfactory for refractory Behçet's uveitis in three consecutive patients
Anti-interleukin 6 receptor antibody tocilizumab was not satisfactory for refractory Behçet's uveitis in three consecutive patients Open
View article: A single nucleotide polymorphism in the IL1RL1 gene is associated with Behcet’s disease in a Chinese Han population
A single nucleotide polymorphism in the IL1RL1 gene is associated with Behcet’s disease in a Chinese Han population Open
AIM: To explore the association of single nucleotide polymorphisms (SNPs) in the IL33/IL1RL1 gene region with the susceptibility to Behcet’s disease (BD) in a Chinese Han population. METHODS: A total of eight SNPs in the candidate gene reg…
View article: Comparison of the Safety and Efficacy of Interferon Alpha-2a and Cyclosporine-A When Combined With Glucocorticoid in the Treatment of Refractory Behçet’s Uveitis: A Randomized Controlled Prospective Study
Comparison of the Safety and Efficacy of Interferon Alpha-2a and Cyclosporine-A When Combined With Glucocorticoid in the Treatment of Refractory Behçet’s Uveitis: A Randomized Controlled Prospective Study Open
Purpose: To evaluate and compare the efficacy and safety of interferon alpha-2a (IFN-α2a) and cyclosporine-A (CsA) in patients with refractory Behçet’s uveitis (BU). Methods: In this 12-month randomized, controlled, prospective trial, 26 p…