Meihua Chen
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View article: Extracellular Matrix Protein Abi3bp’S Vsv Antiviral Mechanism: Preliminary Study
Extracellular Matrix Protein Abi3bp’S Vsv Antiviral Mechanism: Preliminary Study Open
Aim or purpose: To explore the influence of extracellular matrix protein ABI3BP on vesicular stomatitis virus (VSV) genome replication and innate immune signaling pathway. Materials and methods: The small interfering RNA (siRNA) was transf…
View article: A self-powered hydration-monitoring and drug-delivery skin patch for closed-loop treatment of atopic dermatitis
A self-powered hydration-monitoring and drug-delivery skin patch for closed-loop treatment of atopic dermatitis Open
Atopic dermatitis is a chronic inflammatory skin condition that typically manifests in infancy and is characterized by dry, irritated skin. Here, we propose a self-powered hydration-monitoring and drug-delivery skin patch for closed-loop t…
View article: The Genetic Elements of the Obesity Paradox in Atherosclerosis Identified in an Intercross Between Hyperlipidemic Mouse Strains
The Genetic Elements of the Obesity Paradox in Atherosclerosis Identified in an Intercross Between Hyperlipidemic Mouse Strains Open
Overweight and obese individuals show lower mortality rates or better prognoses than those of normal weight in a variety of diseases, a phenomenon called the “obesity paradox”. An inverse association of adiposity with atherosclerosis has b…
View article: Cancer associated fibroblasts in cancer development and therapy
Cancer associated fibroblasts in cancer development and therapy Open
Cancer-associated fibroblasts (CAFs) are key players in cancer development and therapy, and they exhibit multifaceted roles in the tumor microenvironment (TME). From their diverse cellular origins, CAFs undergo phenotypic and functional tr…
View article: Effectiveness of OH card-based group mental health education in improving mood and behavior in breast cancer patients
Effectiveness of OH card-based group mental health education in improving mood and behavior in breast cancer patients Open
Purpose Psychological disorders and different coping styles often occur after breast cancer (BC) diagnosis. The purpose of this study was to explore the effect of OH card on psychological status and coping styles of individuals with breast…
View article: Prevalence and factors associated with informal advance care planning discussion and do-not-resuscitate directives in patients at geriatric clinics
Prevalence and factors associated with informal advance care planning discussion and do-not-resuscitate directives in patients at geriatric clinics Open
While Taiwanese older outpatients often informally discussed ACP, the completion of DNR directives was less common. The link between higher geriatric comorbidity and DNR directives highlights the need for proactive, tailored interventions …
View article: Associations of the gut, cervical, and vaginal microbiota with cervical cancer: a systematic review and meta-analysis
Associations of the gut, cervical, and vaginal microbiota with cervical cancer: a systematic review and meta-analysis Open
View article: Incidence and risk of endocrine and metabolic abnormalities linked to PARP inhibitors in solid tumors: a meta-analysis
Incidence and risk of endocrine and metabolic abnormalities linked to PARP inhibitors in solid tumors: a meta-analysis Open
View article: Serum Pharmacochemistry and Network Pharmacology Reveal Active Compounds and Mechanisms of the Huaxian Formula in Alleviating Radiation-Induced Pulmonary Fibrosis
Serum Pharmacochemistry and Network Pharmacology Reveal Active Compounds and Mechanisms of the Huaxian Formula in Alleviating Radiation-Induced Pulmonary Fibrosis Open
Our research results indicate that HXF may exert its effects on the prevention and treatment of radiation-induced pulmonary fibrosis (RIPF) through multiple pathways and targets, with the PI3K-Akt signaling pathway likely playing the most …
View article: What Should We Teach in Esp Writing Course? A Case Study of 16-Year International Publishing Experiences of a Chinese Faculty Member in Electronics and Information
What Should We Teach in Esp Writing Course? A Case Study of 16-Year International Publishing Experiences of a Chinese Faculty Member in Electronics and Information Open
View article: Role of Oral Microbiota Balance and Probiotic Therapy in Radiation-Induced Oral Mucositis
Role of Oral Microbiota Balance and Probiotic Therapy in Radiation-Induced Oral Mucositis Open
View article: An esophageal stent integrated with wireless battery-free movable photodynamic-therapy unit for targeted tumor treatment
An esophageal stent integrated with wireless battery-free movable photodynamic-therapy unit for targeted tumor treatment Open
Esophageal cancer is the eighth most common cancer worldwide and the sixth leading cause of cancer-related deaths. In this study, we propose a novel esophageal stent equipped with a wireless, battery-free, and movable photodynamic therapy …
View article: Topical 5-aminolevulinic acid photodynamic therapy for genital vitiligo
Topical 5-aminolevulinic acid photodynamic therapy for genital vitiligo Open
Vitiligo is an acquired chronic depigmentary skin disorder which results from the destruction of melanocytes. The clinical characteristic of vitiligo is the development of white macules due to the loss of functioning melanocytes in the ski…
View article: Huaxian formula prevents the progression of radiation-induced pulmonary fibrosis by inhibiting the pro-fibrotic effects of macrophages
Huaxian formula prevents the progression of radiation-induced pulmonary fibrosis by inhibiting the pro-fibrotic effects of macrophages Open
HXF's preventive effects on RIPF involve multiple targets and mechanisms, including the modulation of Arg1, Mmp10, and Fgf23 expression. By inhibiting the pro-fibrotic capacity of macrophages, HXF suppresses fibroblast activation and colla…
View article: LINC01410 accelerates the invasion of trophoblast cells by modulating METTL3/Fas
LINC01410 accelerates the invasion of trophoblast cells by modulating METTL3/Fas Open
View article: Author Correction: ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice
Author Correction: ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice Open
View article: Acute atopic dermatitis and urticaria imprints peripheral monocytes with proinflammatory-prone signature
Acute atopic dermatitis and urticaria imprints peripheral monocytes with proinflammatory-prone signature Open
Background IL-4 and IL-13, pivotal components of type 2 immunity, have been implicated in inducing trained immunity in myeloid cells. However, the precise inflammatory response of monocytes in individuals with type 2 immune disorders remai…
View article: A Self-Powered Lactate Sensor Based on the Piezoelectric Effect for Assessing Tumor Development
A Self-Powered Lactate Sensor Based on the Piezoelectric Effect for Assessing Tumor Development Open
The build-up of lactate in solid tumors stands as a crucial and early occurrence in malignancy development, and the concentration of lactate in the tumor microenvironment may be a more sensitive indicator for analyzing primary tumors. In t…
View article: ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice
ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice Open
View article: Effects of an integrated ambulatory care program on healthcare utilization and costs in older patients with multimorbidity: a propensity score-matched cohort study
Effects of an integrated ambulatory care program on healthcare utilization and costs in older patients with multimorbidity: a propensity score-matched cohort study Open
View article: Identification of ferroptosis-associated tumor antigens as the potential targets to prevent head and neck squamous cell carcinoma
Identification of ferroptosis-associated tumor antigens as the potential targets to prevent head and neck squamous cell carcinoma Open
View article: Antiviral Effect of Extracellular Matrix Protein ABI3BP on Vesicular Stomatitis Virus and Its Mechanism: A Preliminary Study <italic>In Vitro</italic>
Antiviral Effect of Extracellular Matrix Protein ABI3BP on Vesicular Stomatitis Virus and Its Mechanism: A Preliminary Study In Vitro Open
Objective To explore the influence of extracellular matrix protein ABI-interactor 3-binding protein (ABI3BP) on vesicular stomatitis virus (VSV) genome replication and innate immune signaling pathway.Methods The small interfering RNA (siRN…
View article: Overcoming Barriers in Photodynamic Therapy Harnessing Nanogenerators Strategies
Overcoming Barriers in Photodynamic Therapy Harnessing Nanogenerators Strategies Open
Photodynamic therapy (PDT) represents a targeted approach for cancer treatment that employs light and photosensitizers (PSs) to induce the generation of reactive oxygen species (ROS). However, PDT faces obstacles including insufficient PS …
View article: Simultaneous Determination of Boron, Arsenic, Antimony, Molybdenum, Bromine, and Iodine in Soil by Ammonia Extraction to Inductively Coupled Plasma-Mass Spectrometry
Simultaneous Determination of Boron, Arsenic, Antimony, Molybdenum, Bromine, and Iodine in Soil by Ammonia Extraction to Inductively Coupled Plasma-Mass Spectrometry Open
View article: Self‐Generated Displacement Current of Triboelectric Nanogenerator for Cancer Therapy: Theory and Application (Adv. Mater. Technol. 2/2024)
Self‐Generated Displacement Current of Triboelectric Nanogenerator for Cancer Therapy: Theory and Application (Adv. Mater. Technol. 2/2024) Open
Triboelectric Nanogenerators Self-generated dynamic electric field or displacement current of triboelectric nanogenerators (TENGs) can operate from micrometers to centimeters, which offers a key technology for TENG based therapy system for…
View article: Piezo-Photodynamic Therapy of Au@PEG-ZnO Nanostructures Enabled with a Battery-Free Wireless Cancer Therapeutic Dot
Piezo-Photodynamic Therapy of Au@PEG-ZnO Nanostructures Enabled with a Battery-Free Wireless Cancer Therapeutic Dot Open
View article: Implanted, Wireless, Self‐Powered Photodynamic Therapeutic Tablet Synergizes with Ferroptosis Inducer for Effective Cancer Treatment
Implanted, Wireless, Self‐Powered Photodynamic Therapeutic Tablet Synergizes with Ferroptosis Inducer for Effective Cancer Treatment Open
The effective and targeted treatment of resistant cancer cells presents a significant challenge. Targeting cell ferroptosis has shown remarkable efficacy against apoptosis‐resistant tumors due to their elevated iron metabolism and oxidativ…
View article: Stereotactic ablative radiotherapy and FAPα-based cancer vaccine suppresses metastatic tumor growth in 4T1 mouse breast cancer
Stereotactic ablative radiotherapy and FAPα-based cancer vaccine suppresses metastatic tumor growth in 4T1 mouse breast cancer Open
These findings provide a novel therapeutic combination of radiation and FAPα-based cancer vaccine with promising results against poorly immunogenic metastatic cancer. This study may pave the way to overcome the therapeutic resistance cause…
View article: 2085P Buprenorphine use and cancer outcomes
2085P Buprenorphine use and cancer outcomes Open
View article: Effect of timing of enteral nutrition initiation on poor prognosis in patients after cardiopulmonary bypass: A prospective observational study
Effect of timing of enteral nutrition initiation on poor prognosis in patients after cardiopulmonary bypass: A prospective observational study Open
Compared with early EN 48 h increased the risk for poor prognosis in patients after CPB.