Meike Bartels
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View article: Genetic and environmental influences on educational disparities in adult weight change: an individual-based pooled analysis of 11 twin cohorts
Genetic and environmental influences on educational disparities in adult weight change: an individual-based pooled analysis of 11 twin cohorts Open
Introduction Educational attainment (EA) is negatively associated with body mass index (BMI) but less is known about the association between EA and adult BMI change. We analyzed the role of genetic and environmental factors in the associat…
View article: Social Mismatch and Affective Wellbeing: An Ecological Momentary Assessment Study
Social Mismatch and Affective Wellbeing: An Ecological Momentary Assessment Study Open
The online version contains supplementary material available at 10.1007/s10902-025-00965-6.
View article: The Hidden Biology of Wellbeing: A Multi-Omics Analysis Across Genomic, Epigenomic, and Transcriptomic Layers
The Hidden Biology of Wellbeing: A Multi-Omics Analysis Across Genomic, Epigenomic, and Transcriptomic Layers Open
Biological systems are composed of multiple molecular layers, including the genome, epigenome, transcriptome, and metabolome. These layers are interconnected and interact, but are often studied independently. Multi-omics approaches aim to …
View article: Epigenome-wide association study meta-analysis of wellbeing
Epigenome-wide association study meta-analysis of wellbeing Open
Wellbeing is associated with both behavioral phenotypes as well as several key life outcomes, such as health, employment, and coping with stressful events. These phenotypes associated with wellbeing could be potential indicators of differe…
View article: Living Happily Ever After: Longitudinal Insights into Enduring Mental Health and Wellbeing
Living Happily Ever After: Longitudinal Insights into Enduring Mental Health and Wellbeing Open
Enduring Mental Health (EMH) has been defined as maintaining good psychological functioning without developing mental health problems. Estimates of the proportion of individuals who have EMH vary widely. We investigated EMH across the life…
View article: Major depression and atherosclerotic disease: Linking shared genetics to pathways in blood, brain, heart, and atherosclerotic plaques
Major depression and atherosclerotic disease: Linking shared genetics to pathways in blood, brain, heart, and atherosclerotic plaques Open
Background The increased risk of atherosclerotic diseases (stroke, coronary artery disease [CAD]) observed in depression may stem from shared pathophysiology. We examined whether: 1) major depression (MD) and atherosclerotic traits share g…
View article: From words to wellbeing: Mining Dutch social media language to quantify wellbeing
From words to wellbeing: Mining Dutch social media language to quantify wellbeing Open
Wellbeing measures, traditionally based on self-reports, could potentially be enhanced with Social Media Text Mining (SMTM), providing dynamic, real-time insights into wellbeing. This study explores the application of SMTM to assess wellbe…
View article: Genome-wide association studies of infant temperament reveal genetic links with later life outcomes
Genome-wide association studies of infant temperament reveal genetic links with later life outcomes Open
We conducted genome-wide association studies on infant temperament – Emotionality, Activity, Shyness and Sociability (N=43,963-72,663) - and meta-analysed the results. We studied the second and third years after birth and a cross-infancy a…
View article: Genome-wide association meta-regression identifies stem cell lineage orchestration as a key driver of acne risk
Genome-wide association meta-regression identifies stem cell lineage orchestration as a key driver of acne risk Open
Over 85% of the population experience acne at some point in their lives, with its severity spanning a quantitative spectrum, from mild, transient outbreaks to more persistent, severe forms of the condition. Moderate to severe disease poses…
View article: O10 Acne polygenic risk score derived from genome-wide association metaregression enables prediction of severity
O10 Acne polygenic risk score derived from genome-wide association metaregression enables prediction of severity Open
Acne vulgaris is highly prevalent, with 85% of the population experiencing it at some point in their lives. Disease severity spans a quantitative spectrum, from mild, transient outbreaks to more persistent, severe forms of the condition. M…
View article: Microbiota and wellbeing: A systematic review of associations with microbial diversity and composition
Microbiota and wellbeing: A systematic review of associations with microbial diversity and composition Open
Interest in the microbiota’s role in wellbeing has significantly grown. This systematic review examined associations between gut and oral microbiota and wellbeing. Results on gut microbial diversity were inconsistent, likely due to methodo…
View article: Genetic and environmental effects on weight gain from young adulthood to old age and its association with body mass index at early young adulthood: an individual-based pooled analysis of 16 twin cohorts
Genetic and environmental effects on weight gain from young adulthood to old age and its association with body mass index at early young adulthood: an individual-based pooled analysis of 16 twin cohorts Open
Introduction Genetic factors contribute to weight gain, but how these effects change over adulthood is still unknown. We studied the impact of genetics on BMI change from young adulthood to old age and its relationship with BMI in early yo…
View article: The association between frequency of social media use, wellbeing, and depressive symptoms: disentangling genetic and environmental factors
The association between frequency of social media use, wellbeing, and depressive symptoms: disentangling genetic and environmental factors Open
Meta-analyses consistently report small but significant associations (around r = -0.10) between wellbeing (WB) and social media use (SMU) and between anxious-depressive symptoms (ADS) and SMU (around r = 0.10). This study employs the class…
View article: Genome-wide association meta-analysis of age at onset of walking in over 70,000 infants of European ancestry
Genome-wide association meta-analysis of age at onset of walking in over 70,000 infants of European ancestry Open
Age at onset of walking is an important early childhood milestone which is used clinically and in public health screening. In this genome-wide association study meta-analysis of age at onset of walking ( N = 70,560 European-ancestry infant…
View article: Enduring Mental Health in Childhood and Adolescence: Prevalence, Prediction, and Genetic Architecture
Enduring Mental Health in Childhood and Adolescence: Prevalence, Prediction, and Genetic Architecture Open
We worked to ensure sex and gender balance in the recruitment of human participants. We worked to ensure that the study questionnaires were prepared in an inclusive way. We worked to ensure race, ethnic, and/or other types of diversity in …
View article: The association between frequency of social media use, wellbeing, and depressive symptoms: disentangling genetic and environmental factors
The association between frequency of social media use, wellbeing, and depressive symptoms: disentangling genetic and environmental factors Open
Meta-analyses consistently report small but significant associations (around r = -0.10) between wellbeing (WB) and social media use (SMU) and between anxious-depressive symptoms (ADS) and SMU (around r = 0.10). This study employs the class…
View article: Detaching From the Nine‐to‐Five: How Retirement and Genetics Are Related to Chronotype
Detaching From the Nine‐to‐Five: How Retirement and Genetics Are Related to Chronotype Open
Our sleep–wake rhythm is determined by the interaction of our work–life balance, that is, the ‘social clock’, and our biological clock. After retirement, the social restrictions generally loosen up, possibly giving more room for our geneti…
View article: Social mismatch and affective wellbeing: a genetically-informative Ecological Momentary Assessment study
Social mismatch and affective wellbeing: a genetically-informative Ecological Momentary Assessment study Open
The affective benefits of social contact depend on momentary social needs. Mismatch between desired and actual contact can result in social deprivation or oversatiation. We examined these dynamics in relation to affective wellbeing, consid…
View article: Implementing Findable, Accessible, Interoperable, Reusable (FAIR) Principles in Child and Adolescent Mental Health Research: Mixed Methods Approach
Implementing Findable, Accessible, Interoperable, Reusable (FAIR) Principles in Child and Adolescent Mental Health Research: Mixed Methods Approach Open
Background The FAIR (Findable, Accessible, Interoperable, Reusable) data principles are a guideline to improve the reusability of data. However, properly implementing these principles is challenging due to a wide range of barriers. Objecti…
View article: Genetic and Environmental Influences on Aggression Across the Lifespan: A Longitudinal Twin Study
Genetic and Environmental Influences on Aggression Across the Lifespan: A Longitudinal Twin Study Open
In this study, we investigated the genetic and environmental contributions to individual differences in aggression across the lifespan, in longitudinal data provided by 32,541 twin pairs aged 3 to over 60 years, from the Netherlands Twin R…
View article: Individual differences in wellbeing dynamics: A genetically-informed comparison of Ecological Momentary Assessment and longitudinal survey data
Individual differences in wellbeing dynamics: A genetically-informed comparison of Ecological Momentary Assessment and longitudinal survey data Open
Variability in wellbeing over time is related to mental health and can be measured at different timescales. Long-term wellbeing dynamics, assessed via longitudinal surveys, capture stability and change over months or years, while short-ter…