Melanie-Anne A. John
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View article: A case series of emtricitabine-induced pure red cell aplasia
A case series of emtricitabine-induced pure red cell aplasia Open
This study provides strong circumstantial evidence that emtricitabine plays an important role in the pathogenesis of reversible PRCA. The mechanisms through which emtricitabine induces PRCA remain unclear and require further study.
View article: Emtricitabine-induced pure red cell aplasia
Emtricitabine-induced pure red cell aplasia Open
Introduction: Anemia is common in HIV. Parvo B19 infection is a well-recognised cause of red cell aplasia. Other causes of persistent pure red cell aplasia (PRCA) include anti-retroviral drugs such as zidovudine and lamivudine. We describe…
View article: Efavirenz challenge in patients with nevirapine induced Stevens-Johnson Syndrome
Efavirenz challenge in patients with nevirapine induced Stevens-Johnson Syndrome Open
Background: Non-nucleoside reverse transcriptase inhibitors (NNRTI) are recommended as part of first-line treatment by the World Health Organisation (WHO) for antiretroviral treatment (ART) naïve subjects. Due to reports of cross-toxicity …
View article: Efavirenz challenge in patients with nevirapine induced Stevens-Johnson Syndrome
Efavirenz challenge in patients with nevirapine induced Stevens-Johnson Syndrome Open
Background: Non-nucleoside reverse transcriptase inhibitors (NNRTI) are recommended as part of first-line treatment by the World Health Organisation (WHO) for antiretroviral treatment (ART) naïve subjects. Due to reports of cross-toxicity …