Mélanie Doré
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View article: A Multimodal and Multi-centric Head and Neck Cancer Dataset for Segmentation, Diagnosis and Outcome Prediction
A Multimodal and Multi-centric Head and Neck Cancer Dataset for Segmentation, Diagnosis and Outcome Prediction Open
We present a publicly available multimodal dataset for head and neck cancer research, comprising 1123 annotated Positron Emission Tomography/Computed Tomography (PET/CT) studies from patients with histologically confirmed disease, acquired…
View article: Extensive and delayed necrosis of a free flap following subtotal glossectomy and adjuvant radiotherapy
Extensive and delayed necrosis of a free flap following subtotal glossectomy and adjuvant radiotherapy Open
Oral tongue squamous cell carcinoma is the most common malignancy of the oral cavity. Treatment of this tumor is based on surgical removal with a centimeter margin, which can be combined with radiotherapy. This case report details a late n…
View article: International Expert-Based Consensus Definition, Classification Criteria, and Minimum Data Elements for Osteoradionecrosis of the Jaw: An Interdisciplinary Modified Delphi Study
International Expert-Based Consensus Definition, Classification Criteria, and Minimum Data Elements for Osteoradionecrosis of the Jaw: An Interdisciplinary Modified Delphi Study Open
View article: Extensive and Delayed Necrosis of a Free Flap Following Subtotal Glossectomy and Adjuvant Radiotherapy
Extensive and Delayed Necrosis of a Free Flap Following Subtotal Glossectomy and Adjuvant Radiotherapy Open
View article: Are Dual-Phase 18F-Fluorodeoxyglucose PET-mpMRI Diagnostic Performances to Distinguish Brain Tumour Radionecrosis/Recurrence after Cranial Radiotherapy Usable in Routine?
Are Dual-Phase 18F-Fluorodeoxyglucose PET-mpMRI Diagnostic Performances to Distinguish Brain Tumour Radionecrosis/Recurrence after Cranial Radiotherapy Usable in Routine? Open
Brain metastases or primary brain tumours had poor prognosis until the use of high dose radiotherapy. However, radionecrosis is a complex challenge in the post-radiotherapy management of these patients due to the difficulty of distinguishi…
View article: Prognostic Factors of Mandibular Osteoradionecrosis Including Accurate Colocalization of Avulsions and Dosimetric Dental Mapping Software, a Case-control Study
Prognostic Factors of Mandibular Osteoradionecrosis Including Accurate Colocalization of Avulsions and Dosimetric Dental Mapping Software, a Case-control Study Open
Dental dose and avulsions are associated with ORN, with a 12% increase in risk with each additional gray. Accurate dose information can help dentists in their decisions after IMRT.
View article: Are Dual-Phase 18F-FDG PET-mpMRI Diagnostic Performances to Distinguish Brain Tumour Radionecrosis/Recurrence after Cranial Radiotherapy usable in routine?
Are Dual-Phase 18F-FDG PET-mpMRI Diagnostic Performances to Distinguish Brain Tumour Radionecrosis/Recurrence after Cranial Radiotherapy usable in routine? Open
Purpose: Radionecrosis is a complex challenge in the post-radiotherapy management of these patients due to the difficulty to distinguish this complication from local tumour recurrence. MRI alone have a variable specificity and sensibility …
View article: International Expert-Based Consensus Definition, Staging Criteria, and Minimum Data Elements for Osteoradionecrosis of the Jaw: An Inter-Disciplinary Modified Delphi Study
International Expert-Based Consensus Definition, Staging Criteria, and Minimum Data Elements for Osteoradionecrosis of the Jaw: An Inter-Disciplinary Modified Delphi Study Open
Purpose Osteoradionecrosis of the jaw (ORNJ) is a severe iatrogenic disease characterized by bone death after radiation therapy (RT) to the head and neck. With over 9 published definitions and at least 16 diagnostic/staging systems, the tr…
View article: Dosimetric feasibility of dose-painting radiotherapy for targeting hypoxia in prostate cancer on a novel ring gantry radiotherapy system.
Dosimetric feasibility of dose-painting radiotherapy for targeting hypoxia in prostate cancer on a novel ring gantry radiotherapy system. Open
73 Background: This study aimed at demonstrating the dosimetric feasibility of tumoral and hypoxia-guided dose escalated radiation therapy in prostate cancer on a novel ring gantry system TPS, based on conventionally fractionated and hypof…
View article: The Sentinel Lymph Node in Treatment Planning: A Narrative Review of Lymph-Flow-Guided Radiotherapy
The Sentinel Lymph Node in Treatment Planning: A Narrative Review of Lymph-Flow-Guided Radiotherapy Open
The sentinel lymph node technique is minimally invasive and used routinely by surgeons, reducing the need for morbid extensive lymph node dissections, which is a significant advantage for cancer staging and treatment decisions. The sentine…
View article: Statistical harmonization can improve the development of a multicenter CT‐based radiomic model predictive of nonresponse to induction chemotherapy in laryngeal cancers
Statistical harmonization can improve the development of a multicenter CT‐based radiomic model predictive of nonresponse to induction chemotherapy in laryngeal cancers Open
Purpose To develop a radiomic model predicting nonresponse to induction chemotherapy in laryngeal cancers, from multicenter pretherapeutic contrast‐enhanced computed tomography (CE‐CT) and evaluate the benefit of feature harmonization in s…
View article: Impact of Neck Dissection in Head and Neck Squamous Cell Carcinomas of Unknown Primary
Impact of Neck Dissection in Head and Neck Squamous Cell Carcinomas of Unknown Primary Open
Purpose: Management of head and neck cancers of unknown primary (HNCUP) combines neck dissection (ND) and radiotherapy, with or without chemotherapy. The prognostic value of ND has hardly been studied in HNCUP. Methods: A retrospective mul…
View article: Recommendations for postoperative radiotherapy in head & neck squamous cell carcinoma in the presence of flaps: A GORTEC internationally-reviewed HNCIG-endorsed consensus
Recommendations for postoperative radiotherapy in head & neck squamous cell carcinoma in the presence of flaps: A GORTEC internationally-reviewed HNCIG-endorsed consensus Open
View article: Brain metastases treated with hypofractionated stereotactic radiotherapy: 8 years experience after Cyberknife installation
Brain metastases treated with hypofractionated stereotactic radiotherapy: 8 years experience after Cyberknife installation Open
View article: Haute Couture or Ready-To-Wear? Tailored Pelvic Radiotherapy for Prostate Cancer Based on Individualized Sentinel Lymph Node Detection
Haute Couture or Ready-To-Wear? Tailored Pelvic Radiotherapy for Prostate Cancer Based on Individualized Sentinel Lymph Node Detection Open
Prostate cancer (PCa) pelvic radiotherapy fields are defined by guidelines that do not consider individual variations in lymphatic drainage. We examined the feasibility of personalized sentinel lymph node (SLN)-based pelvic irradiation in …
View article: Can Comprehensive Geriatric Assessment Predict Tolerance of Radiotherapy for Localized Prostate Cancer in Men Aged 75 Years or Older?
Can Comprehensive Geriatric Assessment Predict Tolerance of Radiotherapy for Localized Prostate Cancer in Men Aged 75 Years or Older? Open
Curative radiotherapy for prostate cancer is common in the elderly. However, concerns about potential toxicity have inhibited access to radiotherapy for this population, for whom preserving quality of life (QoL) is crucial. The primary end…
View article: Unilateral or bilateral irradiation in cervical lymph node metastases of unknown primary? A retrospective cohort study
Unilateral or bilateral irradiation in cervical lymph node metastases of unknown primary? A retrospective cohort study Open
View article: Combined abiraterone acetate plus prednisone, salvage prostate bed radiotherapy and LH-RH agonists (CARLHA-GEP12) in biochemically-relapsing prostate cancer patients following prostatectomy: A phase I study of the GETUG/GEP
Combined abiraterone acetate plus prednisone, salvage prostate bed radiotherapy and LH-RH agonists (CARLHA-GEP12) in biochemically-relapsing prostate cancer patients following prostatectomy: A phase I study of the GETUG/GEP Open
When AA was administered without goserilin, only 78% achieved castration levels. AA combined with SRT and goserilin did not increase pelvic toxicity, but lead to an unsuspected high frequency of grade 3 liver toxicity. The phase II recomme…
View article: Comprehensive Geriatric Assessment and quality of life after localized prostate cancer radiotherapy in elderly patients
Comprehensive Geriatric Assessment and quality of life after localized prostate cancer radiotherapy in elderly patients Open
Despite sometimes markedly diminished oncogeriatric parameters, prostate cancer radiotherapy was generally well tolerated in these elderly patients. We found no predictive factor to determine which patients would experience impaired qualit…
View article: Evaluation of tumor hypoxia prior to radiotherapy in intermediate-risk prostate cancer using 18F-fluoromisonidazole PET/CT: a pilot study
Evaluation of tumor hypoxia prior to radiotherapy in intermediate-risk prostate cancer using 18F-fluoromisonidazole PET/CT: a pilot study Open
This is the first study regarding hypoxia imaging using FMISO in prostate cancer showing that a small FMISO-positive volume was detected in one third of intermediate-risk prostate cancer patients.
View article: Hypofractionated irradiation in elderly patients with breast cancer after breast conserving surgery and mastectomy : Analysis of 205 cases
Hypofractionated irradiation in elderly patients with breast cancer after breast conserving surgery and mastectomy : Analysis of 205 cases Open