Melanie Halim
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View article: Tools for investigating host-microbe crosstalk using glycan analysis probes inspired by human lectins
Tools for investigating host-microbe crosstalk using glycan analysis probes inspired by human lectins Open
Human lectins are critical carbohydrate-binding proteins that recognize diverse glycoconjugates from microorganisms and can play a key role in host–microbe interactions. Despite their importance in immune recognition and microbe binding, t…
View article: Glycan analysis probes inspired by human lectins for investigating host-microbe crosstalk
Glycan analysis probes inspired by human lectins for investigating host-microbe crosstalk Open
Human lectins are critical carbohydrate-binding proteins that recognize diverse glycoconjugates from microorganisms and can play a key role in host-microbe interactions. Despite their importance in immune recognition and pathogen binding, …
View article: Lectin-Seq: A method to profile lectin-microbe interactions in native communities
Lectin-Seq: A method to profile lectin-microbe interactions in native communities Open
Soluble human lectins are critical components of innate immunity. Genetic models suggest that lectins influence host-resident microbiota, but their specificity for commensal and mutualist species is understudied. Elucidating lectins’ roles…
View article: Lectin Fingerprinting Distinguishes Antibody Neutralization in SARS-CoV-2
Lectin Fingerprinting Distinguishes Antibody Neutralization in SARS-CoV-2 Open
To develop a method that reports on changes in SARS-CoV-2 spike glycosylation and their impact on antibody protection.
View article: Lectin-Seq: a method to profile lectin-microbe interactions in native communities
Lectin-Seq: a method to profile lectin-microbe interactions in native communities Open
Soluble human lectins are critical components of innate immunity. Genetic models suggest lectins influence host-resident microbiota, but their specificity for commensal and mutualist species is understudied. Elucidating lectins’ roles in r…