Mélina Georget
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View article: Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes
Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes Open
Senescent cells (SnCs) have been described to accumulate in osteoarthritis (OA) joint tissues in response to injury, thereby participating in OA development and progression. However, clinical therapeutic approaches targeting SnCs using sen…
View article: Osteoarthritic chondrocytes undergo a glycolysis-related metabolic switch upon exposure to IL-1b or TNF
Osteoarthritic chondrocytes undergo a glycolysis-related metabolic switch upon exposure to IL-1b or TNF Open
View article: Development of chondrocytes senescence model and role of O-GlcNAcylation in osteoarthritis
Development of chondrocytes senescence model and role of O-GlcNAcylation in osteoarthritis Open
L’Arthrose (OA) touche tous les composants de l’articulation et se caractérise notamment par une dégradation du cartilage, un remodelage de l’os sous-chondral, la formation d’ostéophytes et une inflammation synoviale. Les patients atteint …