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View article: The Effect of Cognitive Rehabilitation on Peripheral Blood B Cell Distribution and Specific Gene Expression Levels in MS patients
The Effect of Cognitive Rehabilitation on Peripheral Blood B Cell Distribution and Specific Gene Expression Levels in MS patients Open
Objective: Multiple Sclerosis (MS) is an autoimmune, demyelinating, and neurological disorder of the central nervous system (CNS).For years, cellular immunity is thought to be the possible potential mechanism in the immunopathogenesis of t…
View article: Expression Levels of B Cell Receptor (BCR) Signaling Pathway Factors are Associated with Conversion from Clinically Isolated Syndrome to Multiple Sclerosis
Expression Levels of B Cell Receptor (BCR) Signaling Pathway Factors are Associated with Conversion from Clinically Isolated Syndrome to Multiple Sclerosis Open
Objective: We have previously shown altered blood B cells in the first attack blood samples of clinically isolated syndrome (CIS) pa-tients, who converted to multiple sclerosis (MS). Our aim was to investigate levels of B cell receptor (BC…
View article: Serum levels of inflammasome pathway factors in clinically isolated syndrome and multiple sclerosis patients: a pilot study
Serum levels of inflammasome pathway factors in clinically isolated syndrome and multiple sclerosis patients: a pilot study Open
Pathogenic roles of nuclear factor kB (NF-kB) pathway and NLRP3 inflammasome complex factors are involved in multiple sclerosis (MS) development. Activation of the NF-kB, NLRP3, and caspase-1 cascade results in production of proinflammator…
View article: B Cell Immunophenotyping and Expression Analysis of B Cell Specific Molecules of Patients with Benign Multiple Sclerosis
B Cell Immunophenotyping and Expression Analysis of B Cell Specific Molecules of Patients with Benign Multiple Sclerosis Open
Objective: Multiple Sclerosis (MS) is a progresive and an immune mediated inflammatory central nervous disease. The focus of this study was to determine the possible relationship between B cell immunophenotypes and related gene expressions…
View article: Cytokine–chemokine and cognitive profile of multiple sclerosis patients with predominant optic nerve and spinal cord involvement
Cytokine–chemokine and cognitive profile of multiple sclerosis patients with predominant optic nerve and spinal cord involvement Open
Context/Objective: Clinical disease activity in multiple sclerosis (MS) may manifest as predominant involvement of optic nerves and spinal cord, as exemplified by opticospinal multiple sclerosis (OSMS) often encountered in Asian countries.…
View article: Synthesis and Applications of Synthetic Peptides
Synthesis and Applications of Synthetic Peptides Open
The synthesis and applications of the peptides are gaining increasing popularity as a result of the developments in biotechnology and bioengineering areas and for a number of research purposes including cancer diagnosis and treatment, anti…
View article: THE ROLE OF NF-κB IN NEURONAL PLASTICITY AND NEURODEGENERATIVE DISEASES
THE ROLE OF NF-κB IN NEURONAL PLASTICITY AND NEURODEGENERATIVE DISEASES Open
NF-κB is a transcription factor emerged by the end of 20th century. At the beginning, NF-κB wasfound to be present in immune cells but following studies showed its presence in almost all cells inan organism. NF-κB takes part in the activat…