Mélissa Galloux
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View article: Clusters of deep intronic RbFox motifs embedded in large assembly of splicing regulators sequences regulate alternative splicing
Clusters of deep intronic RbFox motifs embedded in large assembly of splicing regulators sequences regulate alternative splicing Open
The RbFox RNA binding proteins regulate alternative splicing of genes governing mammalian development and organ function. They bind to the RNA sequence (U)GCAUG with high affinity but also non-canonical secondary motifs in a concentration …
View article: Svid12 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity
Svid12 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity Open
Supplementary Video 12. HT-29 Matrigel Days 0-3.
View article: Svid11 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity
Svid11 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity Open
Supplementary Video 11. HT-29 Collagen I Days 0-3.
View article: Svid8 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity
Svid8 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity Open
Supplementary Video 8. CT26 Matrigel Days 0-3.
View article: Svid7 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity
Svid7 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity Open
Supplementary Video 7. CT26 Collagen I Days 0-3.
View article: Svid2 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity
Svid2 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity Open
Supplementary Video 2. MC38 SIS ECM Days 0-3.
View article: Svid10 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity
Svid10 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity Open
Supplementary Video 10. HT-29 SIS ECM Days 0-3.
View article: Supplementary Figures from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity
Supplementary Figures from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity Open
Supplementary Figures S1-S32
View article: Svid3 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity
Svid3 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity Open
Supplementary Video 3. MC38 Collagen I Days 0-3.
View article: Svid6 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity
Svid6 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity Open
Supplementary Video 6. CT26 SIS ECM Days 0-3.
View article: Svid9 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity
Svid9 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity Open
Supplementary Video 9. HT-29 Cells Alone Days 0-3.
View article: Svid4 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity
Svid4 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity Open
Supplementary Video 4. MC38 Matrigel Days 0-3.
View article: Supplementary Materials from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity
Supplementary Materials from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity Open
Supplementary Materials including extended Materials and Methods, Results, Discussion and References.
View article: Data from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity
Data from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity Open
Three-dimensional (3D) in vitro cell culture models are invaluable tools for investigating the tumor microenvironment. However, analyzing the impact of critical stromal elements, such as extracellular matrix (ECM), remains a challenge. In …
View article: Svid1 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity
Svid1 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity Open
Supplementary Video 1. MC38 Cells Alone Days 0-3.
View article: Supplementary Tables from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity
Supplementary Tables from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity Open
Supplementary Tables
View article: Svid5 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity
Svid5 from A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates <i>In Vivo</i> Tumor Phenotypes and Heterogeneity Open
Supplementary Video 5. CT26 Cells Alone Days 0-3.
View article: Clusters of deep intronic RbFox motifs embedded in large assembly of splicing regulators sequences regulate alternative splicing
Clusters of deep intronic RbFox motifs embedded in large assembly of splicing regulators sequences regulate alternative splicing Open
The RbFox RNA binding proteins regulate alternative splicing of genes governing mammalian development and organ function. They bind to the RNA sequence (U)GCAUG with high affinity but also non-canonical secondary motifs in a concentration …
View article: An HERV-W<i>ENV</i>transcription in atypical memory B cells linked to COVID-19 evolution and risk for long COVID can express the encoded protein from a ribosome readthrough of mRNA from chromosome X
An HERV-W<i>ENV</i>transcription in atypical memory B cells linked to COVID-19 evolution and risk for long COVID can express the encoded protein from a ribosome readthrough of mRNA from chromosome X Open
The human genome comprises 8% of endogenous retroviruses (HERVs). Though HERVS contribute to physiological functions, copies retained pathogenic potential. The HERV-W ENV protein was shown expressed in patients with worse COVID-19 symptoms…
View article: Engineering Tumor Stroma Morphogenesis Using Dynamic Cell-Matrix Spheroid Assembly
Engineering Tumor Stroma Morphogenesis Using Dynamic Cell-Matrix Spheroid Assembly Open
The tumor microenvironment consists of resident tumor cells organized within a compositionally diverse, three-dimensional (3D) extracellular matrix (ECM) network that cannot be replicated in vitro using bottom-up synthesis. We report a new…
View article: Saturation genome editing of 11 codons and exon 13 of BRCA2 coupled with chemotherapeutic drug response accurately determines pathogenicity of variants
Saturation genome editing of 11 codons and exon 13 of BRCA2 coupled with chemotherapeutic drug response accurately determines pathogenicity of variants Open
The unknown pathogenicity of a significant number of variants found in cancer-related genes is attributed to limited epidemiological data, resulting in their classification as variant of uncertain significance (VUS). To date, Breast Cancer…
View article: CK2 signaling from TOLLIP-dependent perinuclear endosomes is an essential feature of<i>KRAS</i>and<i>NRAS</i>mutant cancers
CK2 signaling from TOLLIP-dependent perinuclear endosomes is an essential feature of<i>KRAS</i>and<i>NRAS</i>mutant cancers Open
Oncogenic RAS induces perinuclear translocation of the effector kinases ERK and CK2 and their scaffold, KSR1, forming endosomal signaling hubs termed perinuclear signaling centers (PSCs). PSCs are present in all cancer cell lines and tissu…