Mélusine Monrose
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View article: Alternative splicing is an FXRα loss-of-function mechanism and impacts energy metabolism in hepatocarcinoma cells
Alternative splicing is an FXRα loss-of-function mechanism and impacts energy metabolism in hepatocarcinoma cells Open
View article: Etude des rôles du récepteur nucléaire CAR dans la physiologie et les physiopathologies testiculaires
Etude des rôles du récepteur nucléaire CAR dans la physiologie et les physiopathologies testiculaires Open
Fertility disorders are a major public health concern since they concern millions of people of reproductive age all over the world. The male factor is involved in 50% of identified cases of infertility within couples, involving qualitative…
View article: Identification of the Role of TGR5 in the Regulation of Leydig Cell Homeostasis
Identification of the Role of TGR5 in the Regulation of Leydig Cell Homeostasis Open
Understanding the regulation of the testicular endocrine function leading to testosterone production is a major objective as the alteration of endocrine function is associated with the development of many diseases such as infertility. In t…
View article: Identification of a Crosstalk among TGR5, GLIS2, and TP53 Signaling Pathways in the Control of Undifferentiated Germ Cell Homeostasis and Chemoresistance
Identification of a Crosstalk among TGR5, GLIS2, and TP53 Signaling Pathways in the Control of Undifferentiated Germ Cell Homeostasis and Chemoresistance Open
Spermatogonial stem cells regenerate and maintain spermatogenesis throughout life, making testis a good model for studying stem cell biology. The effects of chemotherapy on fertility have been well‐documented previously. This study investi…
View article: Analysis of the Reversible Impact of the Chemodrug Busulfan on Mouse Testes
Analysis of the Reversible Impact of the Chemodrug Busulfan on Mouse Testes Open
Spermatogenesis is a process within the testis that leads to the production of spermatozoa. It is based on a population of spermatogonial stem cells, which have the capacity to self-renew and to differentiate throughout life to ensure the …
View article: Metallome Deregulation and Health-Related Impacts Due to Long-Term Volcanic Ash Exposure: New Chemical and Isotopic Insights from La Soufrière De Guadeloupe Volcano
Metallome Deregulation and Health-Related Impacts Due to Long-Term Volcanic Ash Exposure: New Chemical and Isotopic Insights from La Soufrière De Guadeloupe Volcano Open
View article: Fxralpha gene is a target gene of hCG signaling pathway and represses hCG induced steroidogenesis
Fxralpha gene is a target gene of hCG signaling pathway and represses hCG induced steroidogenesis Open
View article: Farnesoid X receptor alpha (FXRα) is a critical actor of the development and pathologies of the male reproductive system
Farnesoid X receptor alpha (FXRα) is a critical actor of the development and pathologies of the male reproductive system Open
View article: Nuclear Receptor Metabolism of Bile Acids and Xenobiotics: A Coordinated Detoxification System with Impact on Health and Diseases
Nuclear Receptor Metabolism of Bile Acids and Xenobiotics: A Coordinated Detoxification System with Impact on Health and Diseases Open
Structural and functional studies have provided numerous insights over the past years on how members of the nuclear hormone receptor superfamily tightly regulate the expression of drug-metabolizing enzymes and transporters. Besides the rol…