Melyssa Negri
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View article: Cochlospermum regium Leaf Extract Gel: A Natural Strategy Against Methicillin-Resistant Staphylococcus aureus
Cochlospermum regium Leaf Extract Gel: A Natural Strategy Against Methicillin-Resistant Staphylococcus aureus Open
Background: Skin infections caused by Staphylococcus aureus represent a major public health concern, and plant extracts, such as those from Cochlospermum regium, have emerged as promising therapeutic alternatives. Methods: This study devel…
View article: EFEITO DA MATRIZ DO BIOFILME DE EXOPHIALA DERMATITIDIS SOBRE O HOSPEDEIRO
EFEITO DA MATRIZ DO BIOFILME DE EXOPHIALA DERMATITIDIS SOBRE O HOSPEDEIRO Open
View article: Anti-Biofilm and Human Nail Permeation Properties of Two Green Propolis Extracts
Anti-Biofilm and Human Nail Permeation Properties of Two Green Propolis Extracts Open
Onychomycosis is the most common nail infection, it has been attributed to fungal biofilms, and its treatment success is uncertain yet, but some natural products seem promising for topical treatment. The use of natural residues can also co…
View article: Spatiotemporal patterns of acute paracoccidioidomycosis hospitalizations in Brazil, 2014-2023
Spatiotemporal patterns of acute paracoccidioidomycosis hospitalizations in Brazil, 2014-2023 Open
Paracoccidioidomycosis (PCM) is a neglected fungal disease with a rising incidence in Brazil, including increasing hospitalizations in previously non-endemic regions outside the Amazon. This study analyzed the spatiotemporal patterns of ac…
View article: Chemical, Chemophenetic and Anticancer Studies of Cattleya Purpurata
Chemical, Chemophenetic and Anticancer Studies of Cattleya Purpurata Open
View article: POTENCIAL ANTIFÚNGICO DE PRODUTOS UTILIZADOS NO CAMPO DA ODONTOLOGIA
POTENCIAL ANTIFÚNGICO DE PRODUTOS UTILIZADOS NO CAMPO DA ODONTOLOGIA Open
Fungos, podem causar infecções na cavidade bucal, favorecidas pelo desequilíbrio na microbiota oral e pelo uso de materiais odontológicos que podem favorecer a formação de biofilme. Antifúngicos empregados no tratamento dessas infecções tê…
View article: CENTRIFUGAÇÃO DIFERENCIAL COMO METODOLOGIA PARA ISOLAMENTO DE VESÍCULA EXTRACELULAR DE Fusarium oxysporum
CENTRIFUGAÇÃO DIFERENCIAL COMO METODOLOGIA PARA ISOLAMENTO DE VESÍCULA EXTRACELULAR DE Fusarium oxysporum Open
Fusarium oxysporum é um fungo conhecido por sua capacidade fitopatogênica e sua crescente ameaça frente à indivíduos imunossuprimidos devido seus amplos fatores de virulência. As vesículas extracelulares (VEs) são responsáveis por carrear …
View article: ESPECTROMETRIA DE MASSA MALDI-TOF PARA IDENTIFICAÇÃO DE Aspergillus spp.
ESPECTROMETRIA DE MASSA MALDI-TOF PARA IDENTIFICAÇÃO DE Aspergillus spp. Open
O gênero Aspergillus compreende várias espécies oportunistas sendo um dos patógenos fúngicos com destaque mundial, perdendo apenas para Candida nas infecções fúngicas. Causando um amplo espectro de infecções, variando de aspergilose alérgi…
View article: CONTAMINAÇÃO AMBIENTAL FÚNGICA EM AMBIENTE CRÍTICO HOSPITALAR - UM RISCO IMINENTE NA UTI NEONATAL E PEDIÁTRICA
CONTAMINAÇÃO AMBIENTAL FÚNGICA EM AMBIENTE CRÍTICO HOSPITALAR - UM RISCO IMINENTE NA UTI NEONATAL E PEDIÁTRICA Open
Nos últimos anos, a incidência de infecções fúngicas têm aumentado, principalmente em ambientes hospitalares, onde os indivíduos estão mais debilitados e vulneráveis. Fato que garante maior relevância em ambientes críticos como as Unidades…
View article: MAGNITUDE DO CONHECIMENTO CIENTÍFICO PERTINENTE ÀS COLEÇÕES FÚNGICAS
MAGNITUDE DO CONHECIMENTO CIENTÍFICO PERTINENTE ÀS COLEÇÕES FÚNGICAS Open
A importância das coleções fúngicas (CF) vão além da preservação, mas dizrespeito à necessidade de novas descobertas e contribuem para o desenvolvimentocientífico e tecnológico. O conhecimento da existência das coleções, condiz com aqueda …
View article: POTENCIAL AÇÃO DE UM MOLÉCULA DE QUORUM SENSING DE Fusarium oxysporum EM Candida tropicalis
POTENCIAL AÇÃO DE UM MOLÉCULA DE QUORUM SENSING DE Fusarium oxysporum EM Candida tropicalis Open
Moléculas de quorum sensing (MQS) têm se destacado no segmento antifúngico,sendo empregadas para inibir o crescimento de diferentes espécies fúngicas, aexemplo de 2-etil-1-hexanol (2-EH), que foi detectado recentemente como MQS deFusarium …
View article: Formulation and Characterization of Nanoemulsion Incorporating Chamomilla recutita L. Extract Stabilized with Hyaluronic Acid
Formulation and Characterization of Nanoemulsion Incorporating Chamomilla recutita L. Extract Stabilized with Hyaluronic Acid Open
Skin lesions are an important health concern, exposing the body to infection risks. Utilizing natural products containing chamomile (Chamomilla recutita L.) holds promise for curative purposes. Additionally, hyaluronic acid (HA), an active…
View article: Prevalence of psoriasis and cutaneous mycoses: A descriptive study in Paraná, Brazil
Prevalence of psoriasis and cutaneous mycoses: A descriptive study in Paraná, Brazil Open
The epidemiology of psoriasis and cutaneous mycoses is scarce in Brazil. Thus, this cross-sectional study aimed to characterize the distribution of these diseases in Paraná. Data was obtained from the Outpatient Information System (SIA - S…
View article: Stilbenes, phenanthrenes and antiproliferative activity of <i>Cattleya intermedia</i>
Stilbenes, phenanthrenes and antiproliferative activity of <i>Cattleya intermedia</i> Open
The phytochemical study of Cattleya intermedia (Orchidaceae) led to the isolation of two new stilbenoids and one new 9,10-dihydrophenanthrene, 4′,5-dihydroxy-2′,3-dimethoxy-dihydrostilbene (1), 3,6′-dihydroxy-4′-methoxy-dihyd…
View article: Impact of invasive fungal infections in men from a state in southern Brazil: A geospatial analysis
Impact of invasive fungal infections in men from a state in southern Brazil: A geospatial analysis Open
Objective To analyse the records of male hospitalisation for fungal infections, including their spatial distribution and the main invasive epidemiological and sociodemographic characteristics in the State of Paraná, Brazil. Methods Spatial…
View article: Candida palmioleophila: A New Emerging Threat in Brazil?
Candida palmioleophila: A New Emerging Threat in Brazil? Open
Human activity directly or indirectly causes climate change, promoting changes in the composition of the atmosphere. This change is beyond the variation of the natural climate. In this manner, climate change could create an environmental p…
View article: In Vitro and Ex Vivo Biofilm-Forming Ability of Rhinocladiella similis and Trichophyton rubrum Isolated from a Mixed Onychomycosis Case
In Vitro and Ex Vivo Biofilm-Forming Ability of Rhinocladiella similis and Trichophyton rubrum Isolated from a Mixed Onychomycosis Case Open
Infections caused by biofilm-forming agents have important implications for world health. Mixed infections, caused by more than one etiological agent, are also an emerging problem, especially regarding the standardization of effective diag…
View article: Case of Mixed Infection of Toenail Caused by Candida parapsilosis and Exophiala dermatitidis and In Vitro Effectiveness of Propolis Extract on Mixed Biofilm
Case of Mixed Infection of Toenail Caused by Candida parapsilosis and Exophiala dermatitidis and In Vitro Effectiveness of Propolis Extract on Mixed Biofilm Open
Onychomycosis is a chronic fungal nail infection caused by several filamentous and yeast-like fungi, such as the genus Candida spp., of great clinical importance. Black yeasts, such as Exophiala dermatitidis, a closely related Candida spp.…
View article: Challenges and perspectives in research and teaching of host pathogen interaction topics: new post-pandemic times to Brazil and other South American countries
Challenges and perspectives in research and teaching of host pathogen interaction topics: new post-pandemic times to Brazil and other South American countries Open
Here is our proposal to improve learning in biomedical sciences for graduate and undergraduate courses with a broad vision integrating disciplines such as molecular cell biology, biochemistry, and biophysics around concepts of pathogen int…
View article: Ascending Renal Infection Following Experimental Candiduria by Candida Tropicalis in Immunocompromised Mice
Ascending Renal Infection Following Experimental Candiduria by Candida Tropicalis in Immunocompromised Mice Open
View article: Challenges and perspectives in research and teaching of host pathogen interaction topics: new post-pandemic times to Brazil and other South American countries
Challenges and perspectives in research and teaching of host pathogen interaction topics: new post-pandemic times to Brazil and other South American countries Open
Here is our proposal to improve learning in biomedical sciences for graduate and undergraduate courses with a broad vision integrating disciplines such as molecular cell biology, biochemistry, and biophysics around concepts of pathogen int…
View article: Performance of Two Extracts Derived from Propolis on Mature Biofilm Produced by Candida albicans
Performance of Two Extracts Derived from Propolis on Mature Biofilm Produced by Candida albicans Open
Species of the Candida genus represent the third most common cause of onychomycosis, the most frequent and difficult to treat nail infection. Onychomycosis has been attributed to fungi organized in biofilm and some natural products have pr…
View article: Fungal biocompounds as strategy to control infection associated with urinary catheter
Fungal biocompounds as strategy to control infection associated with urinary catheter Open
Catheter-associated urinary tract infections continue to be of concern, given the growth of epidemiological data, costs, bacterial resistance, and complications and morbidity. Bioprospection of plants as a strategy to control pathogenic mi…
View article: Efficacy of Propolis Gel on Mature Biofilm Formed by Neocosmospora keratoplastica Isolated from Onychomycosis
Efficacy of Propolis Gel on Mature Biofilm Formed by Neocosmospora keratoplastica Isolated from Onychomycosis Open
This article describes Neocosmospora keratoplastica as an etiological onychomycosis agent. Ex vivo studies were initially performed to demonstrate the ability of this species to grow and form a well-organized characteristic biofilm on ster…
View article: Farnesol modulation of Rhodotorula mucilaginosa in biofilm and planktonic forms
Farnesol modulation of Rhodotorula mucilaginosa in biofilm and planktonic forms Open
Biofilms are important to the virulence of human pathogenic fungi, and some molecules have been found to play key roles in the growth and regulation of fungal biofilms. Farnesol, one of these molecules, is well-described for some microorga…
View article: Evaluation of biofilm formation on acrylic resin surfaces coated with silicon dioxide: an in situ study
Evaluation of biofilm formation on acrylic resin surfaces coated with silicon dioxide: an in situ study Open
Biofilm on acrylic resin dental prostheses may cause gingival inflammation. This study evaluated the influence of a silicon dioxide coating layer applied onto acrylic resin on the adhesion of microorganisms. Blocks (5 x 5 x 3 mm) of acryli…
View article: Evaluation of biofilm formation on acrylic resin surfaces coated with silicon dioxide: an in situ study
Evaluation of biofilm formation on acrylic resin surfaces coated with silicon dioxide: an in situ study Open
Biofilm on acrylic resin dental prostheses may cause gingival inflammation. This study evaluated the influence of a silicon dioxide coating layer applied onto acrylic resin on the adhesion of microorganisms. Blocks (5 x 5 x 3 mm) of acryli…
View article: Promising effect of propolis and a by-product on planktonic cells and biofilm formation by the main agents of human fungal infections
Promising effect of propolis and a by-product on planktonic cells and biofilm formation by the main agents of human fungal infections Open
Few antifungals available today are effective in treating biofilms. Thus, it is urgent to discover new compounds, such as natural products, that provide improvements to existing treatments or the development of new antifungal therapies. Th…
View article: Standardization of resazurin use in susceptibility testing of natural products against yeasts in planktonic cells and in biofilms formation
Standardization of resazurin use in susceptibility testing of natural products against yeasts in planktonic cells and in biofilms formation Open
Natural products, such as the ethanolic propolis extract (PE), have been shown to be a safe and effective therapeutic alternative for the treatment of fungal skin and nail diseases. However, the presence of the resin and the physicochemica…
View article: Insight into the Antifungals Used to Address Human Infection Due to <i>Trichosporon</i> Spp.: A Scoping Review
Insight into the Antifungals Used to Address Human Infection Due to <i>Trichosporon</i> Spp.: A Scoping Review Open
Trichosporonosis infections have been increasing worldwide. Providing adequate treatment for these infections remains a challenge. This scoping review contains information about potential antifungals to treat this pathology. Using online d…