Meng H. Tan
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View article: The correlation between temperature and the incidence of acute ischaemic stroke in Yanji, China: a time series study
The correlation between temperature and the incidence of acute ischaemic stroke in Yanji, China: a time series study Open
Objective Acute ischaemic stroke (AIS) is a common cerebrovascular disease; however, the relationship between temperature and its onset remains unclear. Therefore, we aimed to explore the association between temperature and the incidence o…
View article: Comparative Effects of Glucose-Lowering Medications on Kidney Outcomes in Type 2 Diabetes
Comparative Effects of Glucose-Lowering Medications on Kidney Outcomes in Type 2 Diabetes Open
Importance Type 2 diabetes (T2D) is the leading cause of kidney disease in the US. It is not known whether glucose-lowering medications differentially affect kidney function. Objective To evaluate kidney outcomes in the Glycemia Reduction …
View article: Evaluation of polygenic risk scores to differentiate between type 1 and type 2 diabetes
Evaluation of polygenic risk scores to differentiate between type 1 and type 2 diabetes Open
Polygenic risk scores (PRS) quantify the genetic liability to disease and are calculated using an individual's genotype profile and disease‐specific genome‐wide association study (GWAS) summary statistics. Type 1 (T1D) and type 2 (T2D) dia…
View article: New-Onset Diabetes and COVID-19: Evidence from a Global Clinical Registry
New-Onset Diabetes and COVID-19: Evidence from a Global Clinical Registry Open
Background Mounting evidence shows association between COVID-19 and new diagnoses of diabetes. It is unclear, however, if COVID-19 increases detection of pre-existing diabetes or if it can induce new-onset of the disease. Methods We establ…
View article: 056 Outcome of endovascular thrombectomy for ultra-long aeromedical transfers: The experience of one ‘hub’ and eleven ‘spoke’ sites covering more than 1.8 million km<sup>2</sup>
056 Outcome of endovascular thrombectomy for ultra-long aeromedical transfers: The experience of one ‘hub’ and eleven ‘spoke’ sites covering more than 1.8 million km<sup>2</sup> Open
Background Local endovascular services for acute stroke in rural and remote regions remain a significant challenge despite higher rates of stroke in these regions. Objectives We present time metrics, logistics, safety and outcome data on s…
View article: Improvement of E Se tea extracts on renal mesangial cell apoptosis and high-fat-diet/streptozotocin-induced diabetic nephropathy
Improvement of E Se tea extracts on renal mesangial cell apoptosis and high-fat-diet/streptozotocin-induced diabetic nephropathy Open
E Se tea, the leaves of Malus toringoides (Rehd.) Hughes, is a kind of traditional beverage, which is often used to relieve hyperglycemia and hyperlipidemia and other symptoms, while its effect on diabetic nephropathy (DN) is still unclear…
View article: Optimization of Metformin in the GRADE Cohort: Effect on Glycemia and Body Weight
Optimization of Metformin in the GRADE Cohort: Effect on Glycemia and Body Weight Open
OBJECTIVE We evaluated the effect of optimizing metformin dosing on glycemia and body weight in type 2 diabetes. RESEARCH DESIGN AND METHODS This was a prespecified analysis of 6,823 participants in the Glycemia Reduction Approaches in Dia…
View article: The Contemporary Prevalence of Diabetic Neuropathy in Type 1 Diabetes: Findings From the T1D Exchange
The Contemporary Prevalence of Diabetic Neuropathy in Type 1 Diabetes: Findings From the T1D Exchange Open
OBJECTIVE To evaluate the contemporary prevalence of diabetic peripheral neuropathy (DPN) in participants with type 1 diabetes in the T1D Exchange Clinic Registry throughout the U.S. RESEARCH DESIGN AND METHODS DPN was assessed with the Mi…
View article: Longitudinal Changes in Continuous Glucose Monitoring Use Among Individuals With Type 1 Diabetes: International Comparison in the German and Austrian DPV and U.S. T1D Exchange Registries
Longitudinal Changes in Continuous Glucose Monitoring Use Among Individuals With Type 1 Diabetes: International Comparison in the German and Austrian DPV and U.S. T1D Exchange Registries Open
Continuous glucose monitoring (CGM) has been demonstrated in randomized trials to improve glucose control in patients with type 1 diabetes (1), but until recently only a minority of participants in the German/Austrian Diabetes Patienten Ve…
View article: Spectrum of immune checkpoint inhibitors-induced endocrinopathies in cancer patients: a scoping review of case reports
Spectrum of immune checkpoint inhibitors-induced endocrinopathies in cancer patients: a scoping review of case reports Open
The spectrum of ICI-induced endocrinopathies is wide (5 glands affected) and their presentation varied (12 endocrinopathies). Clinical reasoning integrating clinical, biochemical and treatment information is needed to properly diagnose and…
View article: Characteristics of insulin-Naïve people with type 2 diabetes who successfully respond to insulin glargine U100 after 24 weeks of treatment: a meta-analysis of individual participant data from 3 randomized clinical trials
Characteristics of insulin-Naïve people with type 2 diabetes who successfully respond to insulin glargine U100 after 24 weeks of treatment: a meta-analysis of individual participant data from 3 randomized clinical trials Open
Baseline characteristics associated with response were identified. The strong predictability of 12-week response suggests that the magnitude of early HbA1c reduction should be considered when assessing response to IGlar. More aggressive IG…
View article: Laboratory and Benchtop Performance of a Mealtime Insulin-Delivery System
Laboratory and Benchtop Performance of a Mealtime Insulin-Delivery System Open
Background: A basal bolus insulin regimen requires multiple daily insulin injections, which might discourage patient adherence. As a potential solution, a mealtime insulin-delivery system—a 3-day wearable bolus-only patch—was designed to m…
View article: Effects of hemoperfusion and continuous renal replacement therapy on patient survival following paraquat poisoning
Effects of hemoperfusion and continuous renal replacement therapy on patient survival following paraquat poisoning Open
Mortality in patients with paraquat (PQ) poisoning is related to plasma PQ levels. Concentrations lower than 5,000 ng/mL are considered critical but curable. This study assessed the effects of hemoperfusion (HP) and continuous renal replac…