Meng Chen
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View article: Paclitaxel and carboplatin combination therapy-induced pure red cell aplasia in endometrial cancer patient and favorable response to low-dose corticosteroid treatment: a case report
Paclitaxel and carboplatin combination therapy-induced pure red cell aplasia in endometrial cancer patient and favorable response to low-dose corticosteroid treatment: a case report Open
This case highlights PRCA as a potential complication of carboplatin-paclitaxel therapy, emphasizing the importance of obtaining reticulocyte counts and bone marrow studies in cases of refractory chemotherapy-induced anemia. Early low-dose…
View article: Root-centered sodium sequestration and transcriptomic regulation under salt and alkali stress in wild soybean (Glycine soja)
Root-centered sodium sequestration and transcriptomic regulation under salt and alkali stress in wild soybean (Glycine soja) Open
Salt and alkali stress are major constraints on soybean productivity, but their distinct impacts during early development remain insufficiently understood. Wild soybean ( Glycine soja ), a valuable genetic resource for stress tolerance, wa…
View article: Numerical Simulation of M-Shaped Multi-Row Pile-Supported Foundation Pit Excavation Based on ABAQUS
Numerical Simulation of M-Shaped Multi-Row Pile-Supported Foundation Pit Excavation Based on ABAQUS Open
The M-shaped multi-row pile foundation retaining structure represents an enhanced version of conventional multi-row anti-sliding support systems. To date, the implementation of M-shaped pile configurations in foundation pit excavations has…
View article: A multisensor high-temperature signaling framework for triggering daytime thermomorphogenesis in Arabidopsis
A multisensor high-temperature signaling framework for triggering daytime thermomorphogenesis in Arabidopsis Open
The phytochrome B (phyB) photoreceptor and EARLY FLOWERING 3 (ELF3) are two major plant thermosensors that monitor high temperatures primarily at night. However, high temperatures naturally occur during the daytime; the mechanism of daytim…
View article: Functionalized turmeric nanovesicles for precision delivery of doxorubicin in colorectal carcinoma treatment
Functionalized turmeric nanovesicles for precision delivery of doxorubicin in colorectal carcinoma treatment Open
Nanoscale vesicles have emerged as promising biocompatible vehicles for precision drug delivery, owing to their inherent therapeutic properties and versatile structural configurations. This study introduces an innovative biomanufacturing s…
View article: Biocontrol effects and underlying mechanism of Bacillus subtilis Pn1 on Panax notoginseng root rot caused by Fusarium solani
Biocontrol effects and underlying mechanism of Bacillus subtilis Pn1 on Panax notoginseng root rot caused by Fusarium solani Open
View article: [Retracted] (‑)‑β‑hydrastine suppresses the proliferation and invasion of human lung adenocarcinoma cells by inhibiting PAK4 kinase activity
[Retracted] (‑)‑β‑hydrastine suppresses the proliferation and invasion of human lung adenocarcinoma cells by inhibiting PAK4 kinase activity Open
Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the flow cytometric data shown in Fig. 4A and Transwell cell migration and invasion assay data in Fig. 6A subsequently ap…
View article: Potential effects of lipid lowering and antioxidant activity of exosomes from Phascolosoma esculenta: in vivo and in vitro studies
Potential effects of lipid lowering and antioxidant activity of exosomes from Phascolosoma esculenta: in vivo and in vitro studies Open
Exosomes released from cells have been shown to play an important role in health and disease due to their potential application in therapy and diagnosis. First of all, we extracted the exosome from Phascolosoma esculenta, and studied the l…
View article: Numerical case study of a clear-air turbulence event over the Tibetan Plateau
Numerical case study of a clear-air turbulence event over the Tibetan Plateau Open
The Tibetan Plateau is known as the “Third Pole”. However, there are few studies on clear-air turbulence (CAT) event over the Tibetan Plateau. On 11 February 2023, a severe clear-air turbulence (CAT) event occurred along Lhasa-Chongqing ro…
View article: Terahertz Irradiation Promotes Angiogenesis in vitro by Enhancing Permeability of the Voltage-Gated Calcium Channel
Terahertz Irradiation Promotes Angiogenesis in vitro by Enhancing Permeability of the Voltage-Gated Calcium Channel Open
Terahertz (THz) waves, positioned between microwave and infrared in the electromagnetic spectrum, have promising applications in medical imaging and biomedicine. In this study, terahertz irradiation at 2.52 THz (100 mW/cm 2 ) did not alter…
View article: A Cross-sectional Study Assessing Gastrointestinal Symptoms, Eating Behavior and Parental Quality of Life in Chinese Infants Consuming Goat Milk-Based Formula or Cow’s Milk-Based Formula
A Cross-sectional Study Assessing Gastrointestinal Symptoms, Eating Behavior and Parental Quality of Life in Chinese Infants Consuming Goat Milk-Based Formula or Cow’s Milk-Based Formula Open
Objectives: Gastrointestinal (GI) symptoms affect approximately half of infants and can adversely impact infants’ and parents’ quality of life. In this cross-sectional study, infants fed goat milk-based infant formula (GMF) and infants fed…
View article: Synthetic Microbial Communities Enhance Pepper Growth and Root Morphology by Regulating Rhizosphere Microbial Communities
Synthetic Microbial Communities Enhance Pepper Growth and Root Morphology by Regulating Rhizosphere Microbial Communities Open
Synthetic microbial community (SynCom) application is efficient in promoting crop yield and soil health. However, few studies have been conducted to enhance pepper growth via modulating rhizosphere microbial communities by SynCom applicati…
View article: A Point-of-Care Testing (POCT) method based on nucleic acid release agent for rapid detection damping-off disease in Panax ginseng
A Point-of-Care Testing (POCT) method based on nucleic acid release agent for rapid detection damping-off disease in Panax ginseng Open
View article: Shexiang Baoxin Pills alleviate doxorubicin-induced cardiotoxicity via the reactive oxygen species-mediated AKT/Bcl-2 pathway
Shexiang Baoxin Pills alleviate doxorubicin-induced cardiotoxicity via the reactive oxygen species-mediated AKT/Bcl-2 pathway Open
Background: Shexiang Baoxin Pill (SBP) is a classical Chinese medicine that improves endothelial function and antioxidant and inflammatory responses. It may also alleviate doxorubicin (DOX)-induced cardiotoxicity. The aim of this study is …
View article: HOT3/eIF5B1 confers Kozak motif-dependent translational control of photosynthesis-associated nuclear genes for chloroplast biogenesis
HOT3/eIF5B1 confers Kozak motif-dependent translational control of photosynthesis-associated nuclear genes for chloroplast biogenesis Open
View article: Pectinesterase activity and gene expression correlate with pathogenesis of Phytophthora infestans
Pectinesterase activity and gene expression correlate with pathogenesis of Phytophthora infestans Open
Late blight caused by Phytophthora infestans is the most devastating disease of potato. Phytophthora infestans produces many secondary metabolites and effector proteins, involved in the pathogenesis, which compromise host defense mechanism…
View article: A circadian clock output functions independently of phyB to sustain daytime PIF3 degradation
A circadian clock output functions independently of phyB to sustain daytime PIF3 degradation Open
The circadian clock is an endogenous oscillator, and its importance lies in its ability to impart rhythmicity on downstream biological processes, or outputs. Our knowledge of output regulation, however, is often limited to an understanding…
View article: Emodin alleviates intestinal ischemia–reperfusion injury through antioxidant stress, anti-inflammatory responses and anti-apoptosis effects via Akt-mediated HO-1 upregulation
Emodin alleviates intestinal ischemia–reperfusion injury through antioxidant stress, anti-inflammatory responses and anti-apoptosis effects via Akt-mediated HO-1 upregulation Open
View article: A multifaceted crosstalk between brassinosteroid and gibberellin regulates the resistance of cucumber to <i>Phytophthora melonis</i>
A multifaceted crosstalk between brassinosteroid and gibberellin regulates the resistance of cucumber to <i>Phytophthora melonis</i> Open
SUMMARY Cucumber plants are highly susceptible to the hemibiotroph oomycete Phytophthora melonis . However, the mechanism of resistance to cucumber blight remains poorly understood. Here, we demonstrated that cucumber plants with impairmen…
View article: Distinguishing individual photobodies using Oligopaints reveals thermo-sensitive and -insensitive phytochrome B condensation at distinct subnuclear locations
Distinguishing individual photobodies using Oligopaints reveals thermo-sensitive and -insensitive phytochrome B condensation at distinct subnuclear locations Open
View article: Photobody formation spatially segregates two opposing phytochrome B signaling actions of PIF5 degradation and stabilization
Photobody formation spatially segregates two opposing phytochrome B signaling actions of PIF5 degradation and stabilization Open
Photoactivation of the plant photoreceptor and thermosensor phytochrome B (PHYB) triggers its condensation into subnuclear membraneless organelles named photobodies (PBs). However, the function of PBs in PHYB signaling remains frustratingl…
View article: Lipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet homeostasis
Lipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet homeostasis Open
Oxidative stress-induced lipid accumulation is mediated by lipid droplets (LDs) homeostasis, which sequester vulnerable unsaturated triglycerides into LDs to prevent further peroxidation. Here we identify the upregulation of lipopolysaccha…
View article: OsSCYL2 is Involved in Regulating ABA Signaling-Mediated Seed Germination in Rice
OsSCYL2 is Involved in Regulating ABA Signaling-Mediated Seed Germination in Rice Open
Seed germination represents a multifaceted biological process influenced by various intrinsic and extrinsic factors. In the present study, our investigation unveiled the regulatory role of OsSCYL2, a gene identified as a facilitator of see…
View article: Transcriptomic profiling of Poa pratensis L. under treatment of various phytohormones
Transcriptomic profiling of Poa pratensis L. under treatment of various phytohormones Open
Poa pratensis L. (Poaceae) is a valuable grass across the north hemisphere, inhabiting diverse environments with wide altitudinal span, where ubiquitous various kinds of stresses. Phytohormones would be helpful to improve tolerance to abio…
View article: Individual tree detection and counting based on high-resolution imagery and the canopy height model data
Individual tree detection and counting based on high-resolution imagery and the canopy height model data Open
Individual Tree Detection-and-Counting (ITDC) is among the important tasks in town areas, and numerous methods are proposed in this direction. Despite their many advantages, still, the proposed methods are inadequate to provide robust resu…
View article: Conjugated Molecularly Imprinted Polymers Based on Covalent Organic Frameworks: Fluorescent Sensing Platform for Specific Capture of Urea and Elimination of Ethyl Carbamate
Conjugated Molecularly Imprinted Polymers Based on Covalent Organic Frameworks: Fluorescent Sensing Platform for Specific Capture of Urea and Elimination of Ethyl Carbamate Open
View article: Comparison of Flavor and Metabolite Differences between Fresh Jujube and Dried Jujube Wines
Comparison of Flavor and Metabolite Differences between Fresh Jujube and Dried Jujube Wines Open
View article: Genome-Wide and Transcriptome Analysis of Jacalin-Related Lectin Genes in Barley and the Functional Characterization of HvHorcH in Low-Nitrogen Tolerance in Arabidopsis
Genome-Wide and Transcriptome Analysis of Jacalin-Related Lectin Genes in Barley and the Functional Characterization of HvHorcH in Low-Nitrogen Tolerance in Arabidopsis Open
The jacalin-related lectins (JRLs) are widely distributed in plants and are involved in plant development and multiple stress responses. However, the characteristics of the HvJRL gene family at the genome-wide level and the roles of JRLs i…
View article: Evaluation of hepatic AMPK, mTORC1, and autophagy-lysosomal pathway in cows with mild or moderate fatty liver
Evaluation of hepatic AMPK, mTORC1, and autophagy-lysosomal pathway in cows with mild or moderate fatty liver Open
The aim of the present study was to investigate the activity of AMPK and mTORC1 as well as TFEB transcriptional activity and autophagy-lysosomal function in the liver of dairy cows with mild fatty liver (FL) and cows with moderate FL. Live…
View article: Photobody formation spatially segregates two opposing phytochrome B signaling actions to titrate plant environmental responses
Photobody formation spatially segregates two opposing phytochrome B signaling actions to titrate plant environmental responses Open
Photoactivation of the plant photoreceptor and thermosensor phytochrome B (PHYB) triggers its condensation into subnuclear photobodies (PBs). However, the function of PBs remains frustratingly elusive. Here, we found that PHYB recruits PHY…